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Home Communications Intelligent-inhaler-providing-feedback-to-both-patient-and-medical-professional

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 Intelligent inhaler providing feedback to both patient and medical professional

Details
Inventors: Mishelevich, David J.; Lanpher, Ted W.; Lanpher, Gregory B.; Long, James;
Assignee: Circadian, Inc. (San Jose, CA)
Primary Examiner: Burr; Edgar S.
Assistant Examiner: Lewis; Aaron J.
Attorney, Agent or Firm: Wilson, Sonsini, Goodrich & Rosati

The present invention detects how much air is inhaled through the inhaler with what time course (including such derived measurements as how much volume is inspired within the bounds of a given flow range) as well as certain events such as the triggering of the release of aerosol. The system can be set up to compare the resultant time course to either (a) a standard target envelope (e.g., one or more of flow, volume, and time) for that patient programmed into the intelligent inhalation device by a healthcare professional. Based on the comparison, the success or failure of effective inhaler actuation and aerosol inspiration can be signaled to the patient (e.g., visually or through sound) and may be recorded with a time and date stamp for later decoding and evaluation of the invention, the device would also possess the ability to signal the patient to continue post-inspiratory breath holding for use in interpreting the success of medication delivery.

DETAILED DESCRIPTION The overall process of the present intelligent inhaler system is shown in FIG.
6A which provides an overview of the protocol for closing the therapeutic loop.
The target profile envelope is selected and inserted (e.
g.
, via a clinical computer-based workstation).
This target envelope is (a) a generic pattern, or (b) a tailored time course based on the patient's individual spirometric values or other input, as appropriate.
The device is used by the patient and at the next visit to the physician's office, the utilization data are extracted and transferred to the clinical workstation where they are reviewed by the physician or other healthcare professional including analysis of trends with respect to previous periods.
The prescription is adjusted if and as appropriate and, if necessary, a new target profile for the given patient and medication is loaded into the intelligent inhaler device.
FIG.
6B is an overview of the process for utilization by the patient.
Initially, the device reminds the patient that it is time to take the medication.
This is used for medications, such as corticosteroids, which are taken over long periods of time rather than in an immediate reaction to an acute event such as an asthmatic episode.
The device is then turned on and the release of aerosol triggered.
Recording of data begins at the start of inspiration or upon actuation of the medication canister, whichever is earliest.
The actual time course of each inhalation is compared to the objective target time course, a comparison derived, and a signal given as to success or failure.
At the end of inhalation, a timer is started which runs for the period of time during which the patient should hold his or her breath.
At the end of ten seconds (or other period as specified), an auditory and/or visual signal is supplied to the patient.
The patient can press a button to signal when breath holding actually ended.
In an alternate embodiment, the patient can signal that event by exhaling (at least initially) back into the hand-held device with the time recorded when an increase in air flow above a specified threshold is detected



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