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Home Cosmetic Surgery Method-and-apparatus-for-skin-absorption-enhancement-and-transdermal-drug-delivery

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 Method and apparatus for skin absorption enhancement and transdermal drug delivery

Details
Inventors: Bernabei, Gian Franco;
Assignee: Mattioli Engineering Ltd. (London, GB)
Primary Examiner: Bockelman; Mark
Assistant Examiner:
Attorney, Agent or Firm: Foley & Lardner LLP

Application of electrical pulses is made in a controlled manner, in order to increase the absorption of substances applied previously on the skin. Optionally, mechanical vibrations may also be provided to the skin to increase the absorption effect. The electrical pulses are provided to the skin by way of an array of electrodes disposed on a vibrating head plate, and the mechanical vibrations are provided to the skin by way of the vibrating head plate being made to vibrate (if that option is utilized). Preferably, the electrical and mechanical vibrations are at the same frequency and phase with respect to each other, in order to increase the absorption effect. Also, at the same time the electrical pulses are provided to the skin, a syringe containing a skin enhancement substance or a drug is actuated so as to move a particular amount of the substance from the skin, whereby the substance is passed through a tube and then into a groove surrounding a central electrode of the array of electrodes disposed on the plate. The substance is absorbed within the skin as a result.

DETAILED DESCRIPTION The present invention is directed to an apparatus and a method for enhancing the absorption of a substance to be applied on the skin.
To accomplish this, the present invention uses a sequence of electrical pulses (between 20 and 200V peak to peak, preferably, and between 50 and 15,000 Hz preferably) provided to electrodes that are placed in contact with the skin.
There is also provided a corresponding surface vibration to the skin, by application of a mechanical vibration to the skin.
The mechanical vibration is preferably of the same frequency and phase as the electrical pulses applied to the skin.
The mechanical vibration is provided by way of a vibrating plate that also contains the electrodes (which provide the electrical stimulus to the skin at the same time the mechanical vibration is provided to the skin).
In an alternative configuration, only electrical pulses are provided to the skin, whereby mechanical vibrations are not utilized.
The substance to be absorbed by the skin is applied to the skin by way of a syringe, which outputs the substance by way of a tube that is connected to an output of the syringe at one end of the tube and where the other end of the tube is disposed adjacent to a groove (or trough) surrounding a central electrode of an array of electrodes.
Such a substance that is provided to the skin may be a cream, liquid or gel (for example, collagen, or cocoa butter, or suntan oil, or other types of skin enhancement lotions), or a drug to be administered into the skin.
The method according to an embodiment of the invention includes: 1) An apparatus which includes the following elements to perform the following treatment: a) a probe having an array of electrodes on a head portion of the probe, with a central electrode disposed at a central location on the head portion and with a plurality of circumferential electrodes disposed around the central electrode.
b) a pulse generator connected to the array of electrodes.
c) a vibrator which vibrates the head portion of the probe at a same time the electrical pulses are provided to the array of electrodes on the head portion



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