 Flavivirus antigen |
| What is claimed is: 1. An antigen consisting essentially of an amino acid sequence represented by ... |
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| Poxvirus containing formulations and process for preparing stable poxvirus containing compositions |
| OF THE INVENTION The present invention provides poxvirus containing formulation, in particular an ... |
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| Screening method for orthopoxvirus antivirals |
| What is claimed is: 1. An assay comprising the steps of: infecting cultured cells with vaccinia ... |
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| Fibrinogen receptor antagonists |
| OF THE INVENTION Compounds of the invention are fibrinogen receptor antagonists which inhibit ... |
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| Cyclic peptides containing Arg-Gly-Asp, and derivatives thereof, as adhesion inhibitors |
| We claim: 1. A cyclopeptide compound of formula I cyclo-(Arg-B-Asp-D-E) I, wherein: B is Gly, Ala, ... |
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| Platelet aggregation inhibitors |
| We claim: 1. A method of treating or preventing a platelet associated ischemic disorder in a ... |
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| Adhesion receptor antagonists |
| What is claimed is: 1. An oxazolidinone compound of formula I ##STR10## wherein R.sup.1 is ##STR11##... |
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| Activation of peptide prodrugs by hK2 |
| What is claimed is: 1. A composition comprising a prodrug, the prodrug comprising a therapeutically ... |
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| Device having diarrhea diagnostic panel |
| The present invention is directed to a device that comprises a sensor adapted to detect one or more ... |
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| Method for the treatment of chemonucleolysis |
| A method of this invention involves a treatment comprising administering to a mammal in need of ... |
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Computer-aided display for comparative gene expression
| Details |
Inventors: Mack, David H.; Khurgin, Elina; Dai, Josie; Gish, Kurt; Snyder, Jim; Balaban, David;
Assignee: Affymetrix, Inc. (Santa Clara, CA)
Primary Examiner: Siew; Jeffrey
Assistant Examiner:
Attorney, Agent or Firm: Townsend and Townsend and Crew LLP
Innovative systems and methods for visualizing information collected from analyzing samples are provided. The samples may include nucleic acids, proteins, or other polymers. Gene expression level as determined from analysis of a nucleic acid sample is one possible analysis result that may be visualized. In one embodiment, a computer system may display the expression levels of multiple genes simultaneously in a way that facilitates user identification of genes whose expression is significant to a characteristic such as disease or resistance to disease. Additionally, the computer system may facilitate display of further information about relevant genes once they are identified. |
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DETAILED DESCRIPTION The present invention provides innovative systems and methods for visualizing information collected from analyzing samples.
The samples may include nucleic acids, proteins, or other polymers.
Gene expression level as determined from analysis of a nucleic acid sample is one possible analysis result that may be visualized.
In one embodiment, a computer system may display the expression levels of multiple genes simultaneously in a way that facilitates user identification of genes whose expression is significant to a characteristic such as disease or resistance to disease.
Additionally, the computer system may facilitate display of further information about relevant genes once they are identified.
A first aspect of the invention provides a computer-implemented method for presenting expression level information as collected from first and second samples.
The method includes steps of: displaying a first axis corresponding to expression level in the first sample, and displaying a second axis substantially perpendicular to the first axis, the second axis corresponding to expression level in the second sample.
The method further includes a step of: for a selected expressed sequence, displaying a mark at a position.
The position is selected relative to the first axis in accordance with an expression level of the selected expressed sequence in the first sample and relative to the second axis in accordance with an expression level of the selected expressed sequence in the second sample.
A particularly useful application is displaying many marks simultaneously for many selected genes to discover which ones of the selected genes may be relevant to the characteristic.
A second aspect of the invention provides a computer-implemented method of presenting sample analysis information.
The method includes steps of: displaying a first axis corresponding to a concentration of a compound in a first sample as determined by monitoring binding of the compound to a selected polymer having binding affinity to the compound, and displaying a second axis substantially perpendicular to the first axis
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Drugs 
