Home | Links | Contact Us | More About Intellectual Property | Bookmark

Search patents:

Home

Drugs

Multideterminant-peptide-antigens

Dermatophagoides nucleic acid molecules, proteins and uses thereof

OF THE INVENTION The present invention provides for isolated proteins having molecular weights ...

Stabilized primate lentivirus envelope glycoproteins

OF THE INVENTION We have discovered a series of novel polypeptides that can (1) enhance the ...

Endothelial-monocyte activating polypeptide III antibodies

What is claimed is: 1. An isolated antibody or fragment thereof that specifically binds to a ...

Bacillus thuringiensis toxins active against scarab pests

We claim: 1. An isolated polynucleotid encoding a toxin which is active against scarab pests, said ...

Growth differentiation factor-8 transgenic mice

The present invention provides a cell growth and differentiation factor, GDF-8, a polynucleotide ...

Method for using phagocytic particles and ATP receptors to deliver antigens to MHC class I receptors to induce immunity against microbial pathogens or tumors or to suppress immunity

OF THE INVENTION This invention provides a method of delivering an antigen to an Class I MHC ...

Modulation of cholesteryl ester transfer protein (CETP) activity

The invention claimed is: 1. A method for treating or preventing atherosclerosis in a human or ...

Nucleic acids, vectors and host cells encoding heregulin

In accordance with the objects of this invention, we have identified and isolated novel ligand ...

Immunoreactive peptides from Epstein-Barr virus

What is claimed is: 1. A polypeptide consisting of an amino acid sequence having the formula: (.phi....

DNA encoding stationary phase, stress response sigma factor from Mycobacterium tuberculosis

OF THE INVENTION It is a discovery of the present invention that entry of M. tuberculosis into a ...

Multideterminant peptide antigens

Details

Inventors: Berzofsky, Jay A.;
Assignee: The United States of America as represented by the Department of Health (Washington, DC)
Primary Examiner: Smith; Lynette F.
Assistant Examiner: Nelson; Brett
Attorney, Agent or Firm: Townsend and Townsend and Crew LLP

This invention relates to the selection and preparation of synthetic peptides which stimulate helper T lymphocyte response to HIV in a wide range of human subjects. These multideterminant peptides are, therefore, useful for the production of vaccines against HIV infection and for diagnostic procedures to test for HIV seroconversion.

DETAILED DESCRIPTION It is one object of the present invention to demonstrate a process for the selection of synthetic peptides that are useful candidates for vaccines against HIV.
Furthermore, a set of particular peptides are described that have demonstrated efficacy in the process above.
Finally, the invention may find application in diagnostic and therapeutic settings.

Related patents

	HIV envelope polypeptides The present invention provides a method for the rational design and preparation of vaccines based on HIV envelope polypeptides. This invention is based on the discovery ...
	Anti-HIV compositions containing native and recombinant peptides OF THE INVENTION Various objects and advantages of the present invention are achieved by compositions and methods of preventing and treating HIV infection. The ...
	HIV immunoassays using gag polypeptides Nucleotide sequences and expression of nucleotide sequences are provided for detecting the presence of complementary sequences associated with a retroviral etiologic ...
	Prevention and treatment of amyloidogenic disease I. General Several amyloidogenic diseases and conditions are characterized by presence of deposits of A.beta. peptide aggregated to an insoluble mass in the brain of a ...
	HIV vaccine What is claimed is: 1. A recombinant human immunodeficiency virus-1 (HIV-1), wherein the natural signal sequence (NSS) of the HIV-1 envelope glycoprotein gp120 of the ...
	Isolated nucleic acid encoding seven transmembrane receptors The present invention is illustrated by the following examples relating to the isolation of human genomic and cDNA sequences encoding the novel 7TM receptors herein ...
	TIE-2 ligands, methods of making and uses thereof What is claimed is: 1. An isolated antibody which specifically binds a ligand wherein the ligand consists of the amino acid sequence of SEQ ID NO: 2. 2. The antibody of ...
	Phthalidyl-isoquinoline derivatives We claim: 1. A compound of the formula ##STR6## wherein each of R.sub.1, R.sub.2, R.sub.4, R.sub.5 and R.sub.6 is lower alkoxy; R.sub.3 is hydrogen or lower alkoxy; and R...
	Immune suppressive product What is claimed is: 1. An oral vaccine, wherein said vaccine comprises a composition wherein said composition comprises a non-antibody fraction of milk and wherein said ...
	Anti-allergy anti-inflammatory composition OF THE INVENTION The following unique features of Nimesulide may prove to be quite beneficial in all allergic disorders. 1) Nimesulide is a potent stabilizer of mast ...

0.024
Archive: All patents - Links Copyright (c)2006 Eipa-patents.org - All rights reserved