Nucleic acids encoding lymphoid CD30 antigen

DETAILED DESCRIPTION We claim: 1.
An isolated nucleic acid molecule comprising a polynucleotide having a sequence encoding the amino acid sequence of SEQ.
ID.
NO.
: 2.
2.
A recombinant vector comprising an isolated nucleic acid of claim 1.
3.
A cell transformed with a recombinant vector of claim 2.
4.
An isolated nucleic acid molecule comprising a polynucleotide having the nucleotide sequence of SEQ.
ID.
NO.
1.
5.
A recombinant vector comprising an isolated nucleic acid of claim 4.
6.
A cell transformed with a recombinant vector of claim 5.
7.
A method for producing a CD30 protein comprising: i) culturing a transformed cell of claim 3 or 6; and ii) recovering CD30 protein produced by the cultured host cell.
8.
A method for preparing a hybridization probe comprising: i) isolating a restriction fragment of the DNA molecule of claim 1 or claim 4 and its complementary strand; ii) nick-translating the restriction fragment of step (i) in the presence of a labeled nucleotide to obtain a labeled hybridization probe.
9.
A hybridization probe prepared according to the method of claim 8.
10.
An isolated nucleic acid molecule comprising a polynucleotide having a nucleotide sequence selected from the group consisting of a sequence encoding the portion of the amino acid sequence of SEQ.
ID.
NO.
2 from residue 19 to residue 379; a sequence encoding the portion of the amino acid sequence of SEQ.
ID.
NO.
2 from residue 408 to residue 595; a sequence encoding the portion of the amino acid sequence of SEQ.
ID.
NO.
2 from residue 19 to residue 93; a sequence encoding the portion of the amino acid sequence of SEQ.
ID.
NO.
2 from residue 112 to residue 416; the sequence from nucleotide 218 to nucleotide 1732 of SEQ.
ID.
NO.
1; the sequence from nucleotide 277 to nucleotide 1359 of SEQ.
ID.
NO.
1; and the sequence from nucleotide 1444 to nucleotide 2007 of SEQ.
ID.
NO.
1.
11.
A recombinant vector comprising an isolated nucleic acid of claim 10.
12.
A cell transformed with a recombinant vector of claim 11.
13.
A hybridization probe comprising the nucleic acid of claim 1 or 10 and a label selected from the group consisting of radioactive atoms, stain groups, or epitopes introduced for systems based on light or enzymatic stain reactions for detection of nucleic acids