TIE-2 ligands, methods of making and uses thereof

DETAILED DESCRIPTION What is claimed is: 1.
An isolated antibody which specifically binds a ligand wherein the ligand consists of the amino acid sequence of SEQ ID NO: 2.
2.
The antibody of claim 1 which is a monoclonal antibody.
3.
A composition comprising the antibody of claim 1 and a carrier.
4.
The antibody of claim 1 which is a chimeric antibody.
5.
The antibody of claim 2 which is a chimeric antibody.
6.
A composition comprising the antibody of claim 2 and a carrier.
7.
The antibody of claim 1 which is a polyclonal antibody.
8.
An isolated antibody fragment which specifically binds a ligand wherein the ligand consists of the amino acid sequence of SEQ ID NO:2.
9.
The antibody fragment of claim 8, wherein the antibody fragment is an F(ab').
sub.
2 fragment or an Fab' fragment.
10.
The antibody fragment of claim 8 comprising a fragment of a monoclonal antibody.
11.
The antibody fragment of claim 10, wherein the antibody fragment is an F(ab').
sub.
2 fragment or an Fab' fragment.




Description: