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Therapy for injured muscles
| Details |
Inventors: Brooks, Gregory F.; Aoki, Kei Roger;
Assignee: Allergan, Inc. (Irvine, CA)
Primary Examiner: Kam; Chih-Min
Assistant Examiner:
Attorney, Agent or Firm: Donovan; Stephen
Methods for treating an injured muscle by local administration of a neurotoxin, such as a botulinum toxin, to promote healing and/or to reduce the pain associated with an injured muscle. |
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DETAILED DESCRIPTION We claim: 1.
A method for treating an injured muscle, the method comprising the step of local administration of a therapeutically effective amount of a botulinum toxin to an injured muscle, thereby facilitating the healing of the injured muscle, wherein the injured muscle is selected from the group consisting of a biceps, knee and shin muscle.
2.
The method of claim 1 wherein the step of local administration is by intramuscular injection.
3.
The method of claim 1 wherein the botulinum toxin immobilizes the injured muscle.
4.
The method of claim 1 wherein the botulinum toxin is effective to immobilize the injured muscle during phase 1 and phase 2 of a repair process of the injured muscle.
5.
The method of claim 1 wherein the botulinum toxin is effective to immobilize the injured muscle during phase 1 of a repair process of the injured muscle.
6.
The method of claim 1 wherein the botulinum toxin is a botulinum toxin type A, B, C.
sub.
1, D, E, F or G.
7.
The method of claim 1 wherein the botulinum toxin is a recombinantly made neurotoxin.
8.
The method of claim 1 further comprising the step of treating the injured muscle with reparative surgery.
9.
The method of claim 1, wherein the botulinum toxin is botulinum toxin type A.
10.
A method for promoting healing of an injured muscle, the method comprising the step of local administration of a therapeutically effective amount of a botulinum toxin type A to an injured muscle, thereby promoting the healing of the injured muscle, wherein the injured muscle is selected from the group consisting of biceps, knee and shin muscle.
Description:
BACKGROUND The present invention relates to methods for treating muscle injuries.
In particular, the present invention relates to a method for treating an injured muscle by administration of a neurotoxin to the injured muscle.
Injuries to muscles include acute injuries to skeletal muscles such as contusions (bruises), lacerations, ischemia, strains, and complete ruptures.
These injuries may cause tremendous pain and can incapacitate the affected person, preventing them from being able to go to work or even to participate in normal daily activities
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