Vaccine for immunizing cats against toxoplasma oocyst shedding
What is claimed is: 1. A method of immunizing cats against Toxoplasmosis without concomitant oocyst shedding by said cats, said method consisting essentially of administering to said cats an effective... Read More
Inventors: Frenkel, Jacob K.; Pfefferkorn, Elmer R.;, Assignee: The University of Kansas (Lawrence, KS); Darmouth College (Hanover, NH) |
Attenuated viruses
We claim: 1. An attenuated poliovirus in which there is a reversal of a base pairing in the part, or in a part corresponding to the part, of the 5' non-coding region of the genome of poliovirus type 3... Read More
Inventors: Almond, Jeffrey William; Minor, Philip David; Skinner, Michael Anthony; Young, Colin Ruaraidh;, Assignee: Brtish Technology Group Limited (London, GB) |
Chimeric nucleic acids and proteins for inhibiting HIV-1 expression
OF THE INVENTION A fusion protein according to the invention includes NS1 and Rev proteins or fragments or derivatives of the NS1 and Rev proteins. The NS1protein, fragment or derivative may be direc... Read More
Inventors: Krug, Robert M.; Qian, Xiao Yan;, Assignee: Rutgers University (Piscataway, NJ) |
Citrus peel extract as 3-hydroxy-3-methylglutaryl CoA(HMG-CoA) reductase inhibitor
OF THE INVENTION The method of the present invention for inhibiting the activity of HMG-CoA in mammal comprises administering citrus peel extract thereto. The citrus may be tangerines, oranges, lemon... Read More
Inventors: Bok, Song-Hae; Son, Kwang-Hee; Jeong, Tae-Sook; Kwon, Byoung-Mog; Kim, Young-Kook; Choi, Doil; Kim, Sung-Uk; Bae, Ki-Hwan; Park, Yong-Bok; Choi, Myung-Sook; Hwang, Ingyu; Moon, Surk-Sik; Kwon, Yong-Kook; Ahn, Jung-Ah; Lee, Eun-Sook;, Assignee: Korea Institute of Science and Technology (Seoul, KR) |
Heat shock-like protein
What is claimed is: 1. An isolated and purified polynucleotide sequence which encodes the heat shock-like protein (HSPRO) of SEQ ID NO:1. 2. A hybridization probe comprising the polynucleotide sequenc... Read More
Inventors: Hillman, Jennifer L.; Shah, Purvi;, Assignee: Incyte Pharmaceuticals, Inc. (Palo Alto, CA) |
Antiviral peptides
OF THE INVENTION While the specification concludes with claims particularly pointing out and specifically claiming the subject matter regarded as forming the present invention, it is believed that th... Read More
Inventors: Schlesinger, Milton J.; Adams, Steven P.;, Assignee: Washington University (St. Louis, MO) |
Immunoglobulins devoid of light chains
We claim: 1. An immunoglobulin comprising two heavy polypeptide chains, each heavy chain consisting of a complete antigen binding site, said immunoglobulin containing a variable (V.sub.HH) region and ... Read More
Inventors: Casterman, Cecile; Hamers, Raymond;, Assignee: Vrije Universiteit Brussel (Brussels, BE) |
Buffered serum substitute for blood oxygen analyzer
What is claimed is: 1. A buffered serum substitute for receiving a blood sample, said serum substitute comprising a 0.9% saline solution containing 5 millimolar of sodium phosphate, sodium chloride, i... Read More
Inventors: Asakura, Toshio; Blume, Horst K.;, Assignee: |
Analytical method for determining volatiles, solids and solvent extractables
What is claimed is: 1. A method for determining amounts of volatiles, solids, and solvent extractable solid in a sample containing the same comprising placing the sample to be analyzed on a sample hol... Read More
Inventors: Collins, Michael J.;, Assignee: CEM Corporation (Matthews, NC) |
Methods for determining the invasiveness of a bladder tumor
Briefly stated, the present invention provides, in one aspect, methods for determining the invasiveness of a bladder tumor. In one embodiment, the method comprises the steps of: (a) isolating a urine ... Read More
Inventors: Houghton, Raymond L.; Van Aken, Morgan; Jones, Tobin K.;, Assignee: Bard Diagnostic Sciences, Inc. (Redmond, WA) |
Compounds for inhibition of protein methylation
In general, the invention features certain novel compounds which inhibit methylation of proteins having a carboxyl-terminal --CAAX motif (C=cysteine, A=aliphatic amino acid, and X=any amino acid). In ... Read More
Inventors: Rando, Robert R.;, Assignee: The President and Fellows of Harvard College (Cambridge, MA) |
Inhibitors of farnesyl protein transferase
OF THE INVENTION Definition of Terms Listed below are definitions of various terms used to describe this invention. These definitions apply to the terms as they are used throughout this specification... Read More
Inventors: Patel, Dinesh V.; Biller, Scott A.;, Assignee: Bristol-Meyers Squibb Company (Princeton, NJ) |
Cerulenin compounds for fatty acid synthesis inhibition
OF THE INVENTION I. FAS The protein FAS (also referred to herein as OA-519) is highly correlated with the most virulent carcinomas. FAS exhibits fatty acid synthase activity. FAS purified from a huma... Read More
Inventors: Royer, Garfield P.; Townsend, Craig A.;, Assignee: Johns Hopkins University (Baltimore, MD); Chektec Corporation (Baltimore, MD) |
Inhibitors of prenyl-protein transferases
OF THE INVENTION The compounds of this invention inhibit the prenylation of proteins by the enzymes geranylgeranyl protein transferase and farnesyl-protein transferase. In a first embodiment of this ... Read More
Inventors: Anthony, Neville J.; Gomez, Robert P.; Omer, Charles A.;, Assignee: Merck & Co., Inc. (Rahway, NJ) |
Tricyclic carbamate compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
OF THE INVENTION As used herein, the following terms are used as defined below unless otherwise indicated: M.sup.+ -represents the molecular ion of the molecule in the mass spectrum; MH.sup.+ -repres... Read More
Inventors: Bishop, W. Robert; Doll, Ronald J.; Mallams, Alan K.; Njoroge, F. George; Petrin, Joanne M.; Piwinski, John J.; Wolin, Ronald L.; Taveras, Arthur G.; Remiszewski, Stacy W.;, Assignee: Schering Corporation (Kenilworth, NJ) |
Genetic alterations associated with cancer
The present invention provides compositions and methods for detecting genetic alterations correlated with cancer. The invention can be used to detect alterations in a 2 MB region at 3q.sup.2 6.3 that ... Read More
Inventors: Shayesteh, Laleh; Gray, Joe W.;, Assignee: The Regents of the University of California (Oakland, CA) |
Methods and reagents to detect and characterize norwalk and related viruses
OF THE INVENTION It is readily apparent to one skilled in the art that various substitutions and modifications may be made to the invention disclosed herein without departing from the scope and spiri... Read More
Inventors: Estes, Mary K.; Jiang, Xi; Graham, David Y.;, Assignee: Baylor College of Medicine (Houston, TX) |
Human medical treatment by aerosol inhalation of immunoglobulin A
OF THE PREFERRED EMBODIMENTS The following description of the preferred embodiment(s) is merely exemplary in nature and is in no way intended to limit the invention, its application, or uses. In one ... Read More
Inventors: Simon, Michael R.;, Assignee: |
Cell culture process and medium for the growth of adherent animal cells
We have now found that it is possible to eliminate cell aggregation in the culture of CHO-derived cell lines by controlling the molar ratio of total inorganic ions and total amino acids present in the... Read More
Inventors: Boraston, Robert Charles;, Assignee: Alusuisse Holdings A.G. (CH) |
Reactor heater
Having thus described our invention and certain embodiments thereof, we claim: 1. In combination, a reaction chamber for producing aluminum chloride from a reaction of chlorine with alumina and carbon... Read More
Inventors: King, Larry K.; Hardwick, Roy E.;, Assignee: Aluminum Company of America (Pittsburgh, PA) |
Electrical leads for a fluid heaters
The present invention sets forth a method and a structure for connecting electrical power to the heating element of a fluid heater, such as a metallic honeycomb heater body of an electrically heated c... Read More
Inventors: Lipp, G. Daniel; Mack, Alfred N.; Schmitt, Paul S.;, Assignee: Corning Incorporated (Corning, NY) |
Electric radiant heater and method for its manufacture
OF A PREFERRED EMBODIMENT FIG. 1 shows a radiant heater provided for fitting below a cooking surface, e.g. a glass ceramic plate. It has a sheet metal support tray 9, which has a shallow dish shape. ... Read More
Inventors: Gross, Martin; Wilde, Eugen; Mohr, Hans; Renz, Werner; Bogdanski, Franz;, Assignee: E.G.O. Elektro-Gerate Blanc und Fischer GmbH & Co. KG (DE) |
Substrate heating mechanism
An object of the present invention is to provide a substrate-heating mechanism in a film formation process, which is capable of preventing contamination of a formed film with a gas released on heating... Read More
Inventors: Okamura, Nobuyuki;, Assignee: Canon Kabushiki Kaisha (Tokyo, JP) |
Method and apparatus for producing an electrically conductive wall from a fabric and a sheet material
It is therefore an object of the present invention to provide a method of the initially named type, with which an electrically conductive wall material can be produced and, nevertheless, the danger of... Read More
Inventors: Trepte, Peter; Luettgens, Guenter;, Assignee: EMPAC Verpackungs GmbH & Co. (Emsdetten, DE) |
Nozzle for coating optical fibers
I claim: 1. A nozzle for applying a protective resin coating to optical fibers, comprising a body essentially consisting of aluminum with a throughgoing passage which forms a frustoconical funnel term... Read More
Inventors: Roba, Giacomo;, Assignee: Cselt Centro Studi e Laboratori Telecomunicazioni S.p.A. (Torino, IT) |
Coating head assembly for elongated strands
An object of the present invention is to provide a split coating head assembly for elongated strands, such as optical fibers, the assembly including first and second complementary mounting blocks, eac... Read More
Inventors: Rosebrooks, Nathan B.;, Assignee: Sancliff, Inc. (Jefferson, MA) |
Device for the direct or indirect application of a liquid or viscid coating medium onto a moving material web
The present invention provides a generic coater that requires less machine space as compared to the state-of-the art equipment. A generic device addresses this requirement in accordance to a first asp... Read More
Inventors: Gottwald, Ingo; Kohl, Bernhard; Reich, Stefan; Mendez-Gallon, Benjamin; Bernert, Richard; Kustermann, Martin; Ueberschar, Manfred; Henninger, Christoph; Kurtz, Ruediger; Hess, Harald;, Assignee: Voith Sulzer Papiertechnik Patent GmbH (Heidenheim, DE) |
Wafer heaters for use in semiconductor-producing apparatus and heating units using such wafer heaters
A first aspect of the present invention has been accomplished to solve the above-mentioned problems possessed by the above-mentioned prior art, and to provide a wafer heater for use in a semiconductor... Read More
Inventors: Soma, Takao; Ushikoshi, Ryusuke; Nobori, Kazuhiro;, Assignee: NGK Insulators, Ltd. (JP) |
Thermal treatment with enhanced intra-wafer, intra-and inter-batch uniformity
It is an object of the present invention to provide novel heat treatment capable of shortening a gas replacement time and reducing an intra wafer process variation and intra- and inter-batch process v... Read More
Inventors: Yuuki, Tomohiro;, Assignee: Yamaha Corporation (Hamamatsu, JP) |
Pipe cleaning using microwave energy
OF INVENTION Microwaves are a versatile form of energy that is applicable to enhance chemical reactions since the energy is locally applied by its vibrational absorption by polar molecules and does n... Read More
Inventors: Cha, Chang Yul;, Assignee: |
Drugs 
