Process for preparing L-carnitine from DL-carnitine
What is claimed is: 1. A process for preparing L-carnitine and salts thereof which comprises subjecting a racemic mixture of DL-carnitine to the fermentative action of a microorganism selected from th... Read More
Inventors: Sih, Charles I.;, Assignee: Wisconsin Alumni Research Foundation (Madison, WI) |
Building elements and their preparation
We claim: 1. An improved building material element having good mechanical properties comprising expanded vermiculite granules coated with 2 to 30% by weight, based on the weight of vermiculite, with a... Read More
Inventors: Wehrmann, Felix; Voelkl, Rene-Hagen; Wojta, Edwin;, Assignee: Isovolta, Osterreichische Isolierstoffwerke Aktiengesellschaft (Wiener Neudorf, AT) |
Monoclonal antibodies reactive with specific antigenic sites on human cytomegalovirus glycoprotein A
OF THE INVENTION Materials and Methods A. Preparation of Viruses HCMV Towne strain and AD169 strain were grown with or without .sup.3 H-glucosamine on human skin fibroblast cultures, harvested and pu... Read More
Inventors: Lussenhop, Nancy O.; Kari, Bruce E.; Gehrz, Richard C.;, Assignee: The Childrens Hospital Incorporated (St. Paul, MN) |
Desulfatohirudins, the preparation thereof and pharmaceutical compositions containing them
What is claimed is: 1. A desulfatohirudin of the formula I ##STR3## or of the formula II ##STR4## wherein the --Cys-- residues are linked in pairs by disulfide bridges in the same manner as in hirudin... Read More
Inventors: Fritz, Hans; Dodt, Johannes; Seemuller, Ursula; Fink, Ernst;, Assignee: Ciba-Geigy Corporation (Ardsley, NY); Plantorgan Werk Heinrich G.E. Christensen KG (Bad Zwischenahn, DE) |
Primitive cell colony stimulating factors and lymphohematopoietic progenitor cells
We claim: 1. A suspension of mammalian, non-murine, non-human cells comprised of pluripotent lymphohematopoietic non-adherent progenitor stem cells (NA cells) substantially free of mature lymphoid and... Read More
Inventors: Lawman, Michael J. P.; Ohmann, Helle B.; Attah-Poku, Samuel K.; Heise-Qualtiere, Janette;, Assignee: University of Saskatchewan (Saskatoon, CA) |
Urine testing module and method of collecting urine antigen
The invention is directed toward a urine antigen testing process. This method uses a removable stackable sealed urine antigen sample container having an interior chamber with primary antibody covalent... Read More
Inventors: Guirguis, Raouf A.;, Assignee: La Mina Ltd. (VG) |
Serum-free production of packaged viral vector
OF THE INVENTION The invention provides a method for the serum-free production of high tilers of packaged and infectious viral vectors. The method involves inoculating fibroblastic packaging cells ca... Read More
Inventors: Bresler, Herbert S.; Knazek, Richard A.;, Assignee: Cellco, Inc. (Germantown, MD) |
Method for protection against reactive oxygen species
Tumor necrosis factor or TNF, as employed herein, refers in general to the various forms of TNF which exhibit one or more biologic properties of tumor necrosis such as tumor cell lysis, inhibition of... Read More
Inventors: Wong, Grace H. W.;, Assignee: Genentech, Inc. (South San Francisco, CA) |
D-GL conjugate therapy
What is claimed is: 1. A method of inhibiting the proliferation of T-Cell Growth Factor-dependent tumor cells in a patient comprising introducing an effective amount of D-GL T-Cell Growth Factor conju... Read More
Inventors: Katz, David H.;, Assignee: La Jolla Pharmaceutical Company (San Diego, CA) |
Process for making biologically active polypeptides based on transforming growth factor-.beta.sequences
The above objects are achieved by the provision of a polypeptide comprising an amino acid sequence of the formula: A-Arg-B-C-D-E-F-G-H-I-J-K, wherein: A is Val, Leu, Ala, or Tyr or a polypeptide that ... Read More
Inventors: Cianciolo, George J.;, Assignee: Genentech, Inc. (South San Francisco, CA) |
Process for preparing triisocyanates
OF THE INVENTION The present invention relates to a process for the production of (cyclo)aliphatic triisocyanates. Phosgenation of triamines and subsequent working-up of the reaction mixture are carr... Read More
Inventors: Bischof, Eric; Dahmer, J urgen; Flink, Andreas; Krohn, Wolfgang; Molnar, Attila;, Assignee: Bayer Aktiengesellschaft (Leverkusen, DE) |
Compositions which inhibit apoptosis, methods of purifying the compositions and uses thereof
The present invention encompasses methods of obtaining compositions that inhibit apoptosis and the compositions obtained thereby. The compositions are termed phytogenic apoptosis inhibitors (PAIs). Th... Read More
Inventors: Bathurst, Ian C.; Bradley, John D.; Tomei, L. David; Barr, Philip J.;, Assignee: LXR Biotechnology Inc. (Richmond, CA) |
Arg-Gly-Asp-Asp-Ser and pharmaceutical compositions and uses thereof
I claim: 1. Pentapeptide having the following formula: ##STR3## (Arg-Gly-Asp-Asp-Ser (SEQ. ID NO.1)). 2. Pentapeptide (SEQ. ID NO.1) according to claim 1, for use as a medicament. 3. Dermatological ph... Read More
Inventors: Rialdi, Giorgio;, Assignee: Vevy Europe S.p.A. (Genoa, IT) |
Preparation process of syndiotactic polyproplene
We claim: 1. A process for preparing a syndiotactic polypropylene comprising washing, at a temperature of from about 0.degree. C. to about 100.degree. C., with a hydrocarbon solvent of propylene, prop... Read More
Inventors: Asanuma, Tadashi; Shiomura, Tetsunosuke; Uchikawa, Nobutaka; Sasaki, Tateyo; Inoue, Norihide; Uchida, Osamu; Iwatani, Tutomu;, Assignee: Mitsui Toatsu Chemicals, Incorporated (Tokyo, JP) |
DNAs encoding genetically engineered low oxygen affinity mutants of human hemoglobin
It is an object of the present invention to provide genetically engineered low oxygen affinity mutants of human hemoglobin. It is another object of the invention to provide a method of increasing tiss... Read More
Inventors: Fischer, James J.; Baserga, Susan J.;, Assignee: Yale University (New Haven, CT) |
Ultra pure hemoglobin solutions and blood-substitutes
Recognizing the long-standing need in the field to develop a blood substitute comprising an oncotically active protein solution capable of transporting oxygen and readily available when massive transf... Read More
Inventors: Rausch, Carl W.; Feola, Mario;, Assignee: Biopure Corporation (Boston, MA) |
Cocaine derivatives
OF THE PREFERRED EMBODIMENTS Novel compounds are described which are used in the generation of antibodies and, in the immunoassay process generally. The compounds are derivatives of cocaine and cocai... Read More
Inventors: Buechler, Kenneth F.;, Assignee: Biosite Diagnostics, Inc. (San Diego, CA) |
Prevention of infectious diseases with hsp90-peptide complexes
OF THE INVENTION Methods and compositions for the prevention and treatment of primary and metastatic neoplastic diseases and infectious diseases and for eliciting an immune response in a human indivi... Read More
Inventors: Srivastava, Pramod K.; Chandawarkar, Rajiv Y.;, Assignee: Fordham University (Bronx, NY) |
Interference - resistant liposome specific binding assay
What is claimed is: 1. A liposome immunoassay method for determining analyte in a sample with reduced interference from endogenous species comprising the steps of: (a) mixing with said sample to form ... Read More
Inventors: Adolfsen, Robert H.; Hedaya, Eddie; Mak, C. Lam; Schwarzberg, Moshe;, Assignee: Technicon Instruments Corporation (Tarrytown, NY) |
Bridge immunoassay
Abbreviations The following list of abbreviations used in herein:
______________________________________
A: absorbance
Ab: antibody
AP: alkaline phosphatase
... Read More
Inventors: LaMotte, III, George B.;, Assignee: Ciba Corning Diagnostics Corp. (Medfield, MA) |
Immunodiagnostic assay using liposomes carrying labels thereof on outer liposome surface
OF THE INVENTION The immunodiagnostic assay procedures described herein comprise, as an essential element or component, a liposome comprising lipid wall portions having covalently bonded thereto, on ... Read More
Inventors: Carbonell, Ruben G.; Kilpatrick, Peter K.; Jones, Matthew A.; Singh, Anup K.;, Assignee: North Carolina State University (Raleigh, NC) |
Monospecific polyclonal antibodies to shiga-like toxins
It is an object of the invention to provide SLT antitoxin and purified polyclonal antibodies to Shiga-like toxins. Another object of the invention is to provide methods for producing the antitoxin and... Read More
Inventors: Krivan, Howard C.; Samuel, James E.;, Assignee: MicroCarb, Inc. (Gaithersburg, MD) |
Method for the production of anti-escherichia. coli O157 : H7 antibody
OF THE INVENTION A detail description will be given of the present invention with reference to the accompanying drawing. FIG. 1 is a process flow of producing anti-E. coli O157:H7 antibodies and util... Read More
Inventors: Chae, Hyun-Seok; Kim, Dong-Woon; Ahn, Chong-Nam; Cho, Sung-Geun; Sim, Jeong-Seok; Kim, Yong-Gon;, Assignee: Republic of Korea (Management: Rural Development Administration) (Suwon, KR) |
Water-soluble yeast extract produced by adding peroxide to growing yeast cells
It is therefore an object of the present invention to provide a yeast cell extract for use in the cosmetic arts which provides the same or better cell stimulatory effects of the prior art while provid... Read More
Inventors: Scholz, Durant B.; Parish, Derek; Schaeffer, Hans;, Assignee: Arch Personal Care Products, L.P. (South Plainfield, NJ) |
Vitamin B12 assay
OF THE INVENTION This invention provides for the development of a process and an immunoassay for determination of the concentration of vitamin B.sub.12 in serum or other body fluids which involves th... Read More
Inventors: Pourfarzaneh, Mohammad T.; Katsilometes, George W.;, Assignee: Bayer Corporation (Tarrytown, NY) |
Method for treating raw materials containing collagen
What is claimed is: 1. A method for conditioning a collagen-containing substrate to adapt it to a subsequent hot-water extraction of collagen and collagen degradation products therefrom, said substrat... Read More
Inventors: Berg, Alexander; Eckmayer, Zdenek; Monsheimer, Rolf; Pfleiderer, Ernst;, Assignee: Rohm GmbH (Darmstadt, DE) |
Nuclear fuel assembly
What we claim is: 1. A nuclear fuel assembly consisting of a cluster of identical canned-fuel pins disposed on a uniform triangular lattice within a sleeve defining a duct through which a coolant is c... Read More
Inventors: Cayol, Andre; Clottes, Georges; Loriot, Pierre; Skok, Jean;, Assignee: Commissariat a l'Energie Atomique (Paris, FR) |
Cell cultivation container
It is the object of the invention to provide a cell cultivation container of the kind referred to, which is so constructed such that when the screw cover is turned in the opening direction a predeterm... Read More
Inventors: Johansson, Arne; Ajslev, Sven;, Assignee: A/S Nunc (Roskilde, DK) |
Tapered bed bioreactor
In accordance with this invention it has been found that a tapered fluidized bed may be utilized as a bioreactor wherein the fluidized phase is a support material having attached or immobilized there... Read More
Inventors: Scott, Charles D.; Hancher, Charles W.;, Assignee: The United States of America as represented by the United States Energy (Washington, DC) |
Media manipulation for preparing biologically active hollow mycelial pellets
OF THE INVENTION When fungi grow in a liquid medium, their mycelia form a loose cotton-like mass. Some mycelial fungi can form pellets when they are grown in a circular action shaking incubator. The ... Read More
Inventors: Gong, Cheng-Shung; Chen, Li-Fu; Tsao, George T.;, Assignee: Purdue Research Foundation (West Lafayette, IN) |
Drugs 
