 Capillary electrophoretic detection of nucleic acids |
| OF THE PREFERRED EMBODIMENTS This invention provides novel methods for the detection and isolation ... |
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| PNA diagnostic methods |
| The present invention provides methods for detecting nucleic acid sequences and/or determining ... |
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| Histidine-containing peptide nucleic acids |
| OF THE INVENTION Specific sequence recognition of DNA or RNA is of increasing importance for the ... |
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| Two-step hybridization and capture of a polynucleotide |
| According to one aspect of the invention, there is disclosed a method of capturing a target ... |
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| Peptide nucleic acid conjugates |
| OF THE INVENTION According to the present invention a PNA oligomer is conjugated to a ligand ... |
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| High throughput assay system |
| This invention provides compositions, apparatus and methods for concurrently performing multiple ... |
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| Synthetic polymers and methods, kits or compositions for modulating the solubility of same |
| As previously discussed, the limited solubility of PNA oligomers, and particularly purine-rich ... |
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| Neurologically-active compounds |
| The inventors have found a class of compounds which are surprisingly selective GABAC receptor ... |
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| Once a day antihistamine and decongestant formulation |
| The present invention is a controlled release pharmaceutical formulation comprising effective ... |
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| Thermostable isomerase and use hereof, in particular for producing tagatose |
| What is claimed is: 1. An L-arabinose isomerase capable of isomerizing D-galactose to D-tagatose, ... |
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Multi-functional chimeric hematopoietic receptor agonists
| Details |
Inventors: Mc Kearn, John P.; McWherter, Charles A.; Feng, Yiqing; Summers, Neena L.; Staten, Nicholas R.; Streeter, Philip R.; Woulfe, Susan L.; Minster, Nancy I.; Minnerly, John C.;
Assignee:
Primary Examiner: Kemmerer; Elizabeth
Assistant Examiner:
Attorney, Agent or Firm: Winstead Sechrest & Minick PC
Disclosed are novel multi-functional chimeric hematopoietic receptor agonist proteins, DNAs which encode the multi-functional chimeric hematopoietic receptor agonist proteins, methods of making the multi-functional chimeric hematopoietic receptor agonist proetiens and methods of using the multi-functional chimeric hematopoietic receptor agonist proteins. |
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DETAILED DESCRIPTION 1.
A hematopoietic protein comprising; an amino acid sequence of the formula: Met-1 R1-L1-R2, Met-2 Ala-1 P1-L1-R2, Ala-1 R1-L1-R2, R1-L1-R2, Met-1 R2-L1-R1, Met-2 Ala-1 R2-L1-R1, Ala-1 R2-L1-R1, R2-L1-R1, Met-1 R1-R2, Met-2 Ala-1 R1-R2, Ala-1 R1-R2, R1-R2, Met-1 R2-R1, Met-2 Ala-1 R2R1, Ala-1 R2-R1, or R2-R1, wherein R1 is a biologically active human flt-3 receptor agonist polypeptide, comprising; a modified flt-3 ligand amino acid sequence of the Formula: SEQ ID NO:466
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Gene Therapy 
