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Gene Therapy

Pharmaceutical-and-diagnostic-business-systems-and-methods

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Pharmaceutical and diagnostic business systems and methods

Details

Inventors: Margus, Bradley A.; Cox, David R.; Fodor, Stephen P. A.;
Assignee: Perlegen Sciences, Inc. (Mountain View, CA)
Primary Examiner: Martinell; James
Assistant Examiner:
Attorney, Agent or Firm: Arnold; Deana A. Shaver, Esq.; Gulshan H.

Improved pharmaceutical and diagnostic business systems and methods are disclosed. One or more genomes are scanned for single nucleotide polymorphisms. The polymorphisms are assigned to haplotype blocks, and representative SNPs from the haplotype blocks are used in association studies for pharmaceutical and diagnostic development.

DETAILED DESCRIPTION Improved business methods, devices, and systems for utilizing genetic information are provided.
According to one embodiment of the invention a business method is provided that includes the steps of scanning the human genome for single nucleotide polymorphisms across more than 10,000,000 bases, including both genic and non-genic regions; grouping said single nucleotide polymorphisms into haplotype blocks; and independently or collaboratively with drug companies using said haplotype blocks in association studies with disease states.
According to another embodiment of the invention a business method is provided that includes the steps of scanning the human genome for common single nucleotide polymorphisms across more than 10,000,000 bases; grouping said common single nucleotide polymorphisms into haplotype blocks; and collaboratively with drug companies, using the haplotype blocks in association studies with disease states.

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