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Home Heart Surgery Delivery-system-and-method-for-interstitial-radiation-therapy

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 Delivery system and method for interstitial radiation therapy

Details
Inventors: Terwilliger, Richard A.; Lamoureux, Gary A.;
Assignee: IdeaMatrix, Inc. (Estes Park, CO)
Primary Examiner: Lacyk; John P.
Assistant Examiner:
Attorney, Agent or Firm: Fliesler Meyer LLP

A delivery system and method for interstitial radiation therapy comprising a substantially axially stiff and longitudinally flexible elongated member made of material, which is bio-absorbable in living tissue and a plurality of radioactive seeds dispersed in a predetermined array within the member. The delivery system and method further customize the member based on a prescription.

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENT In accordance with an embodiment of the invention, a substantially axially, semi-rigid and longitudinally flexible elongated member made of material, which is bio-absorbable in living tissue, is provided for insertion in tumors.
A plurality of radioactive seeds are encapsulated and positioned in a predetermined array in the member in the desired spaced relationships.
The seeds can be of various types having low energy and low half-life such as Iodine seeds, known as I-125 seeds, consisting of a welded titanium capsule containing iodine 125 absorbed on a silver rod, or Palladium 103 seeds.
Examples of radioactive seeds used to manufacture the therapeutic element appear in Table 1 below.
TABLE-US-00001 TABLE 1 Seed Manufacturers and Common Types of Seeds.
PART NUMBER MANUFACTURER SEED NAME IODINE.
sup.
125 80040-A Amersham 6702 OncoSeed 80040-B Amersham 6711 RAPID Strand 80040-C North American Scientific IoGold 80040-D Best Industries BEST Iodine-125 80040-E Bebig Symmetra 80040-F Mills Biopharmaceuticals ProstaSeed 80040-G Syncor PharmaSeed 80040-H International Isotopes IsoStar 80040-I Implant Sciences I-Plant 80040-J International Brachytherapy InterSource-125 80040-K Source Tech STM 1251 80040-L DRAXIMAGE, Inc.
BrachySeed PALLADIUM.
sup.
103 80035-A North American Scientific Pd Gold 80035-B Theragenics Theraseed 200 80035-C Best Industries BEST Palladium-103 80035-D International Brachytherapy InterSource 103 Additionally, seeds can be manufactured using iridium 192, cesium 131, gold 198, yttrium 90 and phosphorus 32.
Further radioactive isotopes used to manufacture seeds are not limited to these examples, but can include other sources of different types of radiation.
In addition it is to be understood that other types of seeds can be used.
In particular, seeds such as those described in U.
S.
Pat.
No.
6,248,057, which patent is incorporated herein by reference and which is entitled Absorbable Brachytherapy and Chemotherapy Delivery Devices and Methods, can be used with the present invention



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