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Home Heart Surgery Method-and-apparatus-for-providing-external-perfusion-lumens-on-balloon-catheters

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 Method and apparatus for providing external perfusion lumens on balloon catheters

Details
Inventors: Klein, Enrique J.; Bajor, Jordan; Alba, Paul; Kaplan, Aaron V.;
Assignee: LocalMed, Inc. (Palo Alto, CA)
Primary Examiner: Green; Randall L.
Assistant Examiner: Van Over; Perry E.
Attorney, Agent or Firm: Townsend and Townsend and Crew LLP

A catheter sleeve includes a radially expansible distal region having a plurality of axial blood perfusion lumens or channels formed thereon. The catheter sleeve may be introduced over a conventional angioplasty balloon catheter with the expansible region lying over the balloon. When the balloon of the angioplasty catheter is expanded, the perfusion lumens will provide a flow path for blood around the expanded balloon. Optionally, the catheter sleeve may further include drug infusion lumens over the radially expansible region. In this way, drugs can be delivered over prolonged periods while the underlying angioplasty balloon is inflated and blood flows through the lumens or channels to perfuse the distal myocardium.

DETAILED DESCRIPTION According to the present invention, methods and apparatus are provided for establishing perfusion blood flow during balloon angioplasty, vascular drug delivery, and related procedures.
In a preferred embodiment, the method and apparatus provide perfusion blood flow during an intravascular drug infusion procedure where a plurality of drug infusion lumens and blood perfusion lumens are radially expanded and engaged against a treatment site using a conventional balloon angioplasty catheter.
In this way, prolonged drug infusion can be performed while maintaining adequate blood perfusion to tissue distal to the site of the procedure.
Apparatus according to the present invention comprise a catheter sleeve including a flexible tubular body.
The flexible tubular body has a proximal end, a distal end, and a central lumen for slidably receiving a balloon angioplasty catheter therethrough.
A portion of the flexible tubular body is radially expansible, usually comprising a plurality of axial slits formed near the distal end of the catheter body.
In this way, an angioplasty catheter having its balloon disposed within the axially slit portion of the catheter will be able to significantly expand the catheter sleeve.
By providing blood flow perfusion means, typically in the form of axial external flow paths comprising channels and/or tubular members having open lumens, over the radially expansible portion, blood perfusion flow can be established over the exterior surface of an angioplasty balloon during drug delivery procedures, prolonged balloon expansion to treat arterial dissection, and the like.
In contrast with previous balloon perfusion catheter designs, where flow is established internally through an interior lumen of the catheter, the present invention establishes flow over the outside wall of the balloon, thus permitting use with even the smallest diameter (lowest profile) balloon angioplasty catheters.
Additionally, such external lumens or channels permit perfusion to branch vessels which is not possible with catheters having internal perfusion lumens



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