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Percutaneous-biofixed-medical-implants

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Percutaneous biofixed medical implants

Details

Inventors: Marotta, James S.; LaTorre, Guy; Batich, Christopher; Hench, Larry L.;
Assignee: USBiomaterials Corp. (Alachua, FL); University of Florida Research Foundation, Inc. (Gainesville, FL)
Primary Examiner: Nguyen; Dinh X.
Assistant Examiner:
Attorney, Agent or Firm: Burns, Doane, Swecker & Mathis, L.L.P.

Percutaneous implants are disclosed including a portion implantable into a patient, a dermal bonding region capable of forming a bond between the implant and a dermal layer of the patient after the implantable portion is implanted into the patient, and the dermal bonding region including a substrate with a discontinuous coating of particulate bioactive glass wherein the average spacing between the particles of bioactive glass is predetermined and at least about 20 microns prior to implantation into the patient. Also disclosed are bioactive coatings including a substrate and fibers and/or particles of bioactive glass distributed on the substrate with a predetermined average interfiber distance of at least about 20 microns.

DETAILED DESCRIPTION The present invention concerns a percutaneous implant including a portion implantable into a patient, a dermal bonding region capable of forming a bond between the implant and a dermal layer of the patient after the implantable portion is implanted into the patient, and the dermal bonding region including a substrate with a discontinuous coating of particulate bioactive glass wherein the average spacing between the particles of bioactive glass is predetermined and averages at least about 20 microns prior to implantation into the patient.
The present invention also relates to coatings including particles of bioactive glass dispersed at predetermined distances.
The present invention further relates to methods of preparing percutaneous implants and coatings.

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