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 Apparatus for parenteral infusion of fluid containing beneficial agent

Details
Inventors: Urquhart, John; Theeuwes, Felix;
Assignee: Alza Corporation (Palo Alto, CA)
Primary Examiner: Truluck; Dalton L.
Assistant Examiner:
Attorney, Agent or Firm: Sabatine; Paul L., Mandell; Edward L.

A parenteral delivery system is disclosed for administering a beneficial agent to a recipient. The system comprises (a) a primary container of a medical fluid; (b) a primary drip chamber in fluid communication with the primary container; (c) a primary formulation chamber in fluid communication with the primary drip chamber and housing an agent dispensing device or a beneficial agent; (d) a secondary container of a medical fluid; (e) a secondary drip chamber in fluid communication with the secondary container; (f) a secondary formulation chamber in fluid communication with the secondary drip chamber and housing an agent dispensing device or a beneficial agent; and (g) a common tubing in communication with the primary formulation chamber and the secondary formulation chamber for communicating the system with the recipient.

DETAILED DESCRIPTION What is claimed is: 1.
A parenteral delivery system for administering a beneficial agent formulation to an animal, the system comprising: (a) a primary reservoir of a pharmaceutically acceptable fluid; (b) a primary path in communication with the reservoir for the flow of a parenterally acceptable fluid therethrough; (c) a formulation chamber in the primary path, the formulation chamber comprising: (1) a wall surrounding a lumen; (2) an inlet for letting fluid from the primary path into the formulation chamber; (3) a beneficial agent in the formulation chamber that forms an agent formulation with fluid that enters the formulation chamber; (4) an agent release means including a permeable film means within the formulation chamber that aids in controlling the rate of release of beneficial agent formulation from the formulation chamber; and, (5) an outlet for letting an agent formulation leave the formulation chamber; (d) a secondary reservoir of a pharmaceutically fluid; (e) a secondary path in communication with the reservoir for the flow of a parenterally acceptable fluid therethrough; (f) a formulation chamber in the secondary path, the formulation chamber comprising: (1) a wall surrounding a lumen; (2) an inlet for letting fluid from the secondary path into the formulation chamber; (3) a beneficial agent in the formulation chamber that forms an agent formulation with fluid that enters the formulation chamber; (4) an agent release means including a permeable film means within the formulation chamber that aids in controlling the rate of release of beneficial agent formulation from the formulation chamber; and, (5) an outlet for letting an agent formulation leave the formulation chamber; and, (g) a common path in communication with the primary path and in communication with the secondary path for receiving agent formulation, which common path, when the parenteral system is in use, is in communication with the animal for administering beneficial agent formulation thereto



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