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Home Liquid Purification Blood-serum-isolation-device

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 Blood serum-isolation device

Details
Inventors: Ferrara, Louis T.;
Assignee:
Primary Examiner: Marantz; Sidney
Assistant Examiner:
Attorney, Agent or Firm:

A blood serum separation unit which includes a tubular structure having openings at each of opposite ends and having a slidable disk element mounted within a base end thereof, having an outside diameter substantially less than an inside diameter of the tubular element such that upon centrifugal action the slidable disk will be slidable therewithin by torque of centrifugal action, and the tubular element being mounted substantially flushly within but removable from an outer tube having an upper open end and having a stopper-plug which when inserted plugs both the outer tubular container and the tubular element located therewithin, the plug being of a composition penetrable by a tubular needle for introducing blood from a subject to space within the tubular container and tubular element, the disk being of a specific gravity intermediate between those specific gravities of blood serum and blood coagulant precipitate whereby upon inversion of the blood-containing tube and the thereafter subjection of the same to centrifugal action forces, the coagulant precipitate is separated and compacted at an upper end of the tubular element by the disk and upon removal of the stopper-plug serum is left isolated in the remaining outer tube base, the coagulant precipitate having been removed with the inner tubular element.

DETAILED DESCRIPTION FIGS.
1 through 6 represent basically a common embodiment, except that in FIG.
6 the preferred lower positioning of the disk 14 is illustrated, whereby when the specimen is added into the interior space 22, most of the blood specimen will initially be above the disk 14, such that upon inversion before centrifugal action, most blood specimen will naturally and inherently remain within the space 22, rather than getting into the outer tube space 29 as might be the case in the positioning of disk 14 as shown in FIG.
4.
The FIG.
6 also illustrates, however a feature common to all of FIGS.
1 through 5, namely the preferred concave lower face of the disk 14 such that when inverted, any blood specimen within the tube base space 29 of tube 12 tends to drain centrally of the concave face 24 into the perforations 25, this being particularly true in that the slidable tube 13 is flush with the inner tube sides of the outer tube 12; in each of the embodiments as represented by typically FIGS.
1 through 6, the chemical and physical properties of the respective inner and outer tubes are conventionally selected such that the inner tube, although flush with the inner surface of the outer tube, is easily slidable within the outer tube.
The result is that the inner tube may be flushly in contact with the outer tube devoid of space therebetween but the inner tube easily inserted into and withdrawn from the outer tube, while the lack of space make it improbable that any blood specimen can get between the outer surface of the inner tube 13 and the inner surface of the outer tube 12, and also makes the drainage from the inner base walls of the outer tube 12 of specimen thereon ascertainable onto the concave surface 24 and through the pores or perforations 25 during the inversion and centrifugal action whereby none of the coagulated centrifuged coagulant precipitate ends up outside of the inner tube 13, whereby contamination of the serum eventually left within the outer tube is avoided.
Thus, the outer tube 12 and inner tube 13 and disk 14 and stopper-plug 15 make up the unitary device 7 shown in the exploded state in FIG



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