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| Drainage basin filter |
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| Drainage filter system for debris and contaminant removal |
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| Top of grate catch basin filter |
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Filter for removing leucocytes
| Details |
Inventors: Ohno, Shinji;
Assignee: Nissoh Corporation (Osaka, JP)
Primary Examiner: Dawson; Robert A.
Assistant Examiner: Kim; Sun Uk
Attorney, Agent or Firm: Armstrong, Westerman, Hattori, McLeland, & Naughton
A filter for removing leucocytes comprising a filter medium, said filter medium being a fibrous material made of a polyester fiber which is treated on its surface with a copolymer containing 40 to 80% by weight of units derived from glucosyloxyethyl methacylate. When the filter of the present invention is used, leucocytes are removed from concentrated platelets or platelet-rich plasma without loss of platelets. |
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DETAILED DESCRIPTION The copolymer containing 40 to 80% by weight of units derived from glucosyloxyethyl methacrylate and other (vinyl) monomers copolymerized therewith is used in the present invention.
When the amounts of the units is less than 40% by weight, the loss of platelets tends to increase.
When the amount of the units is more than 80% by weight, the removal rate of leucocytes tends to lower.
Glucosyloxyethyl methacrylate is synthesized by direct coupling of 2-hydroxyethyl methacrylate with some aldoses such as glucose, galactose, mannose and xylose.
Examples of the other copolymerizable monomers are, for instance, acrylic acid, methacrylic acid, an alkyl acrylate and an alkyl methacrylate such as methyl methacrylate, hydroxyethyl methacrylate, and the like.
The glucosyloxyethyl methacrylate copolymer in the present invention can be obtained according to a usual process for copolymerization such as bulk polymerization, solution polymerization, suspension polymerization, emulsion polymerization and radiation polymerization using the above mentioned monomers.
As a polyester fiber usable in the present invention, there are, for example, polyethylene terephthalate and the like.
In the present invention, the diameter of a polyester fiber is 1 to 10 .
mu.
m.
When the diameter is less than 1 .
mu.
m, it becomes difficult to prepare a filter medium because the strength of the fiber is too small.
When the diameter is more than 10 .
mu.
m, the removal rate of leucocytes lowers because the filtration capacity lowers due to the small surface area of the fiber.
As a fibrous material in the present invention, there are, for example, a nonwoven fabric, a fleece and the like made of a polyester fiber.
Such material can be prepared according to a usual process from a polyester fiber.
In the present invention, the fibrous material made of a polyester fiber is treated on its surface with the glucosyloxyethyl methacrylate copolymer to give a filter medium.
In the fibrous material, the amount of the copolymer is 0
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