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Method for sterilizing artificial organs and apparatus used therefor
| Details |
Inventors: Masuhara, Shohei;
Assignee: Kanegafuchi Kagaki Kogyo Kabushiki (Osaka, JP)
Primary Examiner: Richman; Barry S.
Assistant Examiner: Kummert; Lynn M.
Attorney, Agent or Firm: Armstrong, Nikaido, Marmelstein & Kubovcik
A method for sterilizing an artificial organ with high pressure steam in an autoclave which comprises passing a sterilized high temperature liquid maintained at a temperature sufficient for the sterilization through the artificial organ, thereby raising the inner temperature of the artificial organ approximately to a sterilization temperature, heating the artificial organ externally to a sterilizing temperature and maintaining that temperature for a predetermined time to sterilize the artificial organ, and passing a sterilized low temperature liquid through the artificial organ to cool it from the inside thereof, while cooling the artificial organ from the outside thereof. The sterilized low temperature liquid is one sterilized thermally followed by cooling, and in a preferable embodiment, the sterilized high temperature liquid is cooled and then introduced into the artificial organ. The sterilizing method is carried out, for instance, by using a high pressure steam sterilization apparatus provided with a storage tank for supplying the sterilized high temperature liquid to an artificial organ accommodated in a high pressure steam sterilizing environment, and a cooling means for cooling the sterilized high temperature liquid, the cooling means being disposed in a pipeline connecting the artificial organ with the storage tank. |
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DETAILED DESCRIPTION In accordance with the present invention, there is provided a method for sterilizing an artificial organ with high pressure steam in an autoclave, which comprises passing through an artificial organ a sterilized high temperature liquid having a temperature high enough to sterilize the artificial organ, thereby raising the inner temperature of the artificial organ substantially to a sterilizing temperature, heating the artificial organ externally to a sterilizing temperature with high pressure steam for a predetermined time to sterilize the artificial organ, and passing a sterilized low temperature liquid through the artificial organ, thereby lowering the inner temperature of the artificial organ.
The sterilization method of the present invention can be effectively practiced using a sterilizing apparatus comprising a pressure vessel for sterilizing an artificial organ with high pressure steam, a tank for holding a sterilized high temperature liquid used for heating the artificial organ from the inside thereof, a pipeline connecting the tank and the artificial organ accomodated in the pressure vessel, and a heat exchanger disposed in the pipeline.
In the method of the present invention, a sterilized liquid having a temperature high enough to sterilize an artificial organ (the sterilized liquid being hereinafter referred to as "sterilized high temperature liquid") is used to rapidly raise the inner temperature of the artificial organ to a high temperature capable of substantially sterilizing the inside of the artificial organ, in addition to high pressure steam for externally heating the artificial organ as in a conventional sterilization method.
After heating the artificial organ to substantially a sterilizing temperature from both the inside and outside thereof, the artificial organ is maintained at the sterilizing temperature for a predetermined period of time enough to achieve sterilization.
Preferably, the inside of the artificial organ should be maintained at a temperature enough to sterilize it also during the sterilization, and this can be attained, for instance, by the high pressure steam heating from the outside of the artificial organ
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Liquid Purification 
