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 Novel assembly

Details
Inventors: Bennett, Michael C.;
Assignee: Becton, Dickinson and Company (East Rutherford, NJ)
Primary Examiner: Hart; Charles N.
Assistant Examiner: Mukai; Robert G.
Attorney, Agent or Firm: Kane, Dalsimer, Kane, Sullivan and Kurucz

Disclosure is made of an improved assembly for the collection, separation and isolation of serum or plasma from blood without subjecting the desired serum or plasma to contamination by exposure to the atmosphere and which utilizes a thixotropic barrier material to effect the isolation. A representative embodiment of the improved assembly comprises an air-evacuated glass collection container, a self-sealing, airtight elastomeric closure for the container which is penetrable by a blood bearing cannula and a thixotrope having a specific gravity of from about 1.03 to about 1.09 disposed in a specially constructed reservoir positioned adjacent to the closure member and within the air-evacuated collection container.

DETAILED DESCRIPTION The invention comprises an assembly for the collection, separation and isolation of serum or plasma from the substantially cellular components of blood, which comprises; A.
MEANS FOR COLLECTING AND ENCLOSING BLOOD WITHOUT EXPOSING SAID BLOOD TO CONTAMINATION BY AIRBORNE CONTAMINANTS; B.
A RESERVOIR ADAPTED TO HOLD A THIXOTROPE SEALANT, DISPOSED COMPLETELY WITHIN SAID MEANS IN A POSITION ABOVE THAT POINT WITHIN SAID MEANS WHICH BECOMES OCCUPIED BY THE COLLECTED AND ENCLOSED BLOOD; C.
A THIXOTROPE SEALANT DISPOSED IN SAID RESERVOIR, SAID THIXOTROPE HAVING A SPECIFIC GRAVITY WITHIN THE RANGE OF FROM ABOUT 1.
03 TO ABOUT 1.
09; AND D.
MEANS OF RELEASING SAID THIXOTROPE AT A POINT BENEATH THE SURFACE OF THE ENCLOSED BLOOD, IN RESPONSE TO CENTRIFUGAL FORCE APPLIED TO THE BLOOD FILLED ASSEMBLY.
The assembly of the invention is useful to protect the desired serum or plasma from contamination by airborne contaminants such as, for example, lead compounds, airborne bacteria, nitrogen oxides and the like which would adversely affect certain diagnostic testing.



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