DETAILED DESCRIPTION Now, however, in accordance with the present invention, there is provided chromatography media in a form which obviates the problems heretofore encountered as discussed above.
The present invention concerns a pellet and method for its manufacture and use where the pellet is a chromatography media characterized by a coherent aggregate of distinct beads having a capacity to resist a force, as demonstrated by a Schleuinger Pharmatron hardness of at least about 2 Kilo Ponds, and capable of being rapidly hydrated on addition of water to form a gel.
In one form, the invention defines a material in the form of a practically dry pellet comprising an aggregate of distinct beads of a selected chromatography media.
On addition of an aqueous medium, the pellet rapidly hydrates to form a chromatography gel wherein the beads are swollen and substantially uniformly dispersed in the aqueous phase.
An additional important feature of the pellet of the present invention is that the aggregate of beads is coherent as characterized as having a Schleuinger Pharmatron hardness, determined as hereinafter described, of at least about 2 Kilo Ponds (KP).
In an additional aspect of this invention, the chromatography media is cross-linked agarose, dextran, or an acrylamide/azlactone copolymer, preferably those varieties thereof which are considered highly cross-linked indicating that the media can resist collapse under high column pressure.
Agarose, designated by the manufacturers as "fast" or "super" flow, is representative of a highly cross-linked media.
Being essentially dry and coherent, pellets can be placed, or as hereinafter described formed in situ, in the wells of microtiter or microfilter plates, and the plates immediately used, stored or shipped for future use; the problems of leakage, spillage and stability encountered with otherwise preformed gels being eliminated.
For use, one needs only add the appropriate aqueous medium and, since hydration occurs almost immediately, rapid assays and high throughputs can be achieved
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Liquid Purification 
