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 Therapeutics plasma exchange system

Details
Inventors: Ford, Michael G.;
Assignee: Baxter International Inc. (Deerfield, IL)
Primary Examiner: Pellegrino; Stephen C.
Assistant Examiner:
Attorney, Agent or Firm: Bostich; June M., Price; Bradford L.

The system includes a plasmapheresis instrument and a harness set applied to the instrument. The harness set has a single venepuncture needle and is configured, when applied to the instrument, to pump blood from a donor through a separator for collection of its constituent parts in a reservoir and a collection container, respectively. During an infusion cycle, which alternates with the collection cycle, the blood constituent from the reservoir and a replacement fluid are mixed externally of the reservoir and pumped to the donor.

DETAILED DESCRIPTION OF THE DRAWING FIGURES Reference will now be made in detail to the present preferred embodiment of the invention, an example of which is illustrated in the accompanying drawings.
A conventional plasmapheresis instrument is generally designated 10 in FIG.
1 and includes various pumps, clamps, detectors, monitoring systems, transducers, indicators and the like, not all of which are described in the present application or necessary to an understanding of the present invention.
Therefore, only those parts of the instrument which are applicable for an understanding of the present invention will be described.
Instrument 10, on its face 12, includes three peristaltic pumps which are individually driven and under the control of a computerized control system.
A blood pump 14 is provided for delivering anticoagulated whole blood from the donor to a separator, described hereinafter, during the collection cycle and for pumping a blood constituent and replacement fluid to the donor during the infusion cycle.
An anticoagulant pump 16 is provided for pumping anticoagulant into the whole blood as the blood enters the harness set.
A cell pump 18 is operable during the blood collection cycle to pump the separated blood constituent from the separator to the reservoir.
In accordance with the present invention, during the infusion cycle, cell pump 18 pumps the replacement fluid from the replacement fluid container and through the separator for mixing with packed cells from the reservoir whereupon blood pump 14 pumps, in the reverse direction from the collection cycle, the mixture of the packed cells and replacement fluid to the donor.
A magnetic motor mount 20 for the separator is also provided on the instrument face 12.
The various clamps include a blood line clamp 22, a reinfusion line clamp 24, a plasma line clamp 26 and a replacement fluid clamp 28.
Additional elements shown on the face of instrument 10 include a pressure transducer assembly 30, a hemoglobin detector 32 and an ultrasonic air detector 34



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