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 Perfluoroalkylether macromer having two polymerizable groups

Details
Inventors: Meijs, Gordon Francis; Laycock, Bronwyn Glenice; Griffiths, Madeleine Clare; Cheong, Edith;
Assignee: Novartis AG (Basel, CH); Commonwealth Scientific and Industrial Research Organisation (Campbell, AU)
Primary Examiner: Lipman; Bernard
Assistant Examiner: Sarofim; N.
Attorney, Agent or Firm: Lee; Michael U.

A macromer of formula (I) is described: Q-(PFPE-L).sub.n-1 -PFPE-Q, wherein n>1.0; PFPE may be the same or different and is a perfluorinated polyether of formula (II): --OCH.sub.2 CF.sub.2 O(CF.sub.2 CF.sub.2 O).sub.x (CF.sub.2 O).sub.y CF.sub.2 CH.sub.2 O--, wherein the CF.sub.2 CF.sub.2 O and CF.sub.2 O units may be randomly distributed or distributed as blocks throughout the chain and wherein x and y may be the same or different such that the molecular weight of the PFPE is in the range of from 242 to 4,000; L is a difunctional linking group; and Q may be the same or different and is a polymerizable group. The macromer may be used preferably in the production of contact lenses.

DETAILED DESCRIPTION The claims defining the invention are as follows: 1.
A macromonomer of the formula I: Q-(PFPE-L).
sub.
n-1 -PFPE-Q (I) wherein n>1.
0; PFPE may be the same or different and is a perfluorinated polyether of formula II: --OCH.
sub.
2 CF.
sub.
2 0(CF.
sub.
2 CF.
sub.
2 0)X(CF.
sub.
2 0)yCF.
sub.
2 CH.
sub.
2 0-- (II) wherein the CF2CF20 and CF20 units may be randomly distributed or distributed as blocks throughout the chain and wherein x and y may be the same or different such that the molecular weight of the PFPE is in the range of from 242 to 4,000; L is a difunctional linking group; and Q may be the same or different and is a ethylenically unsaturated polymerizable group, wherein said macromer is free of polyalkylether segments.
2.
A macromonomer according to claim 1 wherein n is in the range of from 2 to 5.
3.
A macromonomer according to claim 1 wherein n is in the range of from 2 to 4.
4.
A macromonomer according to claim 1 wherein Q is a polymerizable group which comprises an ethylenically unsaturated moiety.
5.
A macromonomer according to claim 1 wherein Q is selected from the group consisting of acryloyl, methacryloyl, styryl, acrylamido, acrylamidoalkyl, urethanemethacrylate, or any substituted derivatives thereof.
6.
A macromonomer according to claim 1 wherein L is a bivalent residue (--C(O)--NH--R--NH--C(O)--) of a diisocyanate wherein R is a divalent organic radical having up to 20 carbon atoms.
7.
A macromonomer according to claim 6 wherein the bivalent residue is derived from a diisocyanate selected from the group consisting of trimethylhexamethylenediisocyanate (TMHMDI), isophorone diisocyanate (IPDI), methylenediphenyl diisocyanate (MDI) and 1,6-hexamethylenediisocyanate (HMDI).
8.
A macromonomer according to claim 1 wherein x is in the range of from 0 to 20.
9.
A macromonomer according to claim 8 wherein x is in the range from 8 to 12.
10.
A macromonomer according to claim 1 wherein y is in the range of from 0 to 25.
11.
A macromonomer according to claim 10 wherein y is in the range from 10 to 14



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