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 Glutaraldehyde sterilizing compositions

Details
Inventors: Cowan, Stanley M.;
Assignee:
Primary Examiner: Robinson; Douglas W.
Assistant Examiner:
Attorney, Agent or Firm: Sim & McBurney

Aqueous solutions of glutaraldehyde of acid pH value contain dissolved quantities of certain highly ionized salts and have the ability to kill dormant spores at room temperature.

DETAILED DESCRIPTION What I claim is: 1.
A method of killing dormant spores, which consists of contacting said spores with a sporicidally-effective amount of a liquid sterilizing composition having a pH from about 2 to less than 7 at a temperature of about 15.
degree.
C.
up to the boiling point of the composition, said sterilizing composition consisting of: a solvent selected from water and a mixture of water and a lower alkanol, 0.
05 to 10% by weight of glutaraldehyde, and at least 0.
01% by weight up to saturation of the composition thereby of at least one highly ionizable neutral salt dissolved in the solvent and selected from the group consisting of lithium, sodium, potassium and ammonium salts of sulphuric acid, hydrochloric acid, nitric acid, citric acid or acetic acid, or mixtures thereof.
2.
The method of claim 1 wherein said composition has a pH of 3 to 6.
5.
3.
The method of claim 2, wherein said composition has a pH of 4.
5 to 5.
5.
4.
The method of claim 1 wherein said glutaraldehyde concentration is 1 to 2% by weight.
5.
The method of claim 1 effected at a temperature of about 20.
degree.
to 25.
degree.
C.
6.
The method of claim 1 wherein said highly ionizable salt concentration is 0.
5 to 1% by weight.
7.
The method of claim 1 effected at a temperature of 20.
degree.
to 25.
degree.
C.
and wherein said composition has a pH of 3 to 6.
5, the glutaraldehyde has a concentration of 1 to 2% by weight and the highly ionizable salt concentration is 0.
5 to 1% by weight.
8.
The method of claim 7 wherein said at least one highly ionizable salt is selected from the group consisting of sodium chloride, ammonium chloride, lithium chloride, potassium chloride, sodium nitrate, potassium nitrate, sodium sulphate, potassium sulphate, sodium citrate, sodium acetate and mixtures of sodium chloride and sodium nitrate and sodium chloride and potassium nitrate.
9.
The method of claim 7 wherein said at least one highly-ionizable salt is sodium chloride and said pH is 4.
5 to 5.
5.
10.
The method of claim 1 including diluting a concentrated form of sterilizing composition containing solvent, glutaraldehyde and salt with solvent to provide said sterilizing composition for utilization in said method



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