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 Machine and process for reading cards containing medical specimens

Details
Inventors: Charles, Ronald A.; Jones, Paul W.; Staples, John L.; Wiegner, Joseph R.;
Assignee: McDonnell Douglas Corporation (St. Louis, MO)
Primary Examiner: Tanenholtz; Alvin E.
Assistant Examiner: Warden; Robert J.
Attorney, Agent or Firm: Gravely, Lieder & Woodruff

Medical specimens suspected of containing certain microorganisms are introduced into cards containing wells having culture media therein. A reduction in the light transmitting characteristics of any well indicates the presence of a microorganism. Each well is examined at periodic intervals by projecting a light through it. This light is monitored by a plurality of detectors located beyond, but nevertheless, in alignment with the well, and each detector provides a signal which is proportional to the intensity of the light cast upon it. If a detector registers an unduly large decrease in light transmission, whereas others associated with the same emitter do not, this probably indicates the presence of a bubble in the well, and the unduly large decrease is ignored. This enables the machine to look around bubbles. Adjustments are made for the change in light transmission caused by distortion of the flexible walls at the ends of the wells. Each card has identification segments which are composed of different bars, and each bar is read by an emitter which projects light through it and a plurality of detectors which are illuminated by the emitter, unless the bar is blocked out with a marking. A predetermined number of the detectors must register a light intensity above a prescribed threshold value to establish the absence of a marking in the bar which is read, and this enables the machine to disregard stray marks and foreign particles on the card. The card is moved incrementally through a reading head as the viewing wells and identification segments on it are read.

DETAILED DESCRIPTION Referring now to the drawings, a microbial analyzing machine A (FIG.
1) examines cuvettes or cards C into which specimens suspected of containing harmful microorganisms have been introduced.
The card C contains dried selective media which is rehydrated by the diluted specimen.
If the specimen contains a microorganism to which one of the media is selective, then the optical characteristics of that particular rehydrated medium will change as the microorganism metabolizes in the medium during incubation.
The machine A detects the changes in light transmitting characteristics of the rehydrated media by projecting light through the rehydrated media.
In addition, the reading machine A detects indicia marked on the cards C and is capable of distinguishing the ten basic cardinal numbers written as Arabic symbols.
These readings are also accomplished by projecting light through the cards C.
The machine A includes a holder H and an extracting unit E (FIG.
5), and the latter is provided with a card reading unit R which reads the indicia on the cards C and examines the rehydrated media for changes in the light transmitting characteristics thereof.
The holder H supports a plurality of cards C in a row with the margins of the cards C being in registration.
All the cards C of the row have the same orientation.
The extracting unit E withdraws the cards C individually from the row and each card C as it is withdrawn is examined by the reading unit R.
Indeed, each rehydrated medium is examined separately and at periodic intervals.
The machine A is controlled by a computer K, and the media and indicia readings derived from the reading unit R are fed to that computer.
The computer K correlates the various media and indicia readings so that the periodic readings derived from particular rehydrated medium of a particular card C are organized in succession.
This enables one to determine if any change in the light transmitting characteristicsmachine A, one being an identification card C.
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