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Means for killing bacterial spores with glutaraldehyde sporicidal compositions
| Details |
Inventors: Winicov, Murray A.; Cantor, Abraham;
Assignee: West Chemical Products, Incorporated (Long Island City, NY)
Primary Examiner: Meyers; Albert T.
Assistant Examiner: Robinson; D. W.
Attorney, Agent or Firm: Thompson, Jr.; Howard E.
This invention relates to new and improved means for killing spores on instruments and the like utilizing the combination of glutaraldehyde and a monoaldehyde, such as, for example, formaldehyde. The sporicidal kill activity of the composition is more rapid than previously possible, and more effective than the use of either glutaraldehyde or monoaldehyde alone. |
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DETAILED DESCRIPTION 1.
A process for killing bacterial spores on instruments, appliances, eating utensils, walls, floors, and beds which comprises treating same with a sporicidally effective amount of a sporicidal composition comprising: a.
a solvent consisting of water b.
0.
5 to 6% by weight glutaraldehyde, and c.
0.
5 to 10% by weight monoaldehyde, said monoaldehyde being selected from the group consisting of formaldehyde, acetaldehyde and propionaldehyde, and said composition being further characterized as having a pH no less 3.
The process of claim 1 wherein the pH of said sporicidal composition is 4.
The process of claim 1 wherein said sporicidal composition contains 2 to 5.
The process of claim 1 wherein said composition contains, as a fourth component (d), at least 0.
1 weight % of a detergent selected from the group consisting of nonionic, anionic, cationic and ampholytic detergents.
6.
The process of claim 5 wherein the amount of said detergent is 0.
1 to 1 7.
A sporicidal composition for treating instruments, consisting essentially of: a.
a solvent consisting of water b.
0.
5 to 6% by weight glutaraldehyde, and c.
0.
5 to 10% weight monoaldehyde, said monoaldehyde being selected from the group consisting of formaldehyde, acetaldehyde and propionaldehyde, and said composition being further characterized as having a pH no less 8.
The sporicidal composition of claim 7 wherein said monoaldehyde is 9.
The sporicidal composition of claim 7 wherein the pH of said sporicidal 10.
The sporicidal composition of claim 7 which contains 2 to 4% 11.
The sporicidal composition of claim 7 which contains 2 to 4% 12.
The sporicidal composition of claim 7, containing as a fourth component d.
at least 0.
1 weight % of a detergent selected from the group consisting 13.
The composition of claim 12 which contains 0.
1 to 1 weight % of said 14.
The sporicidal composition of claim 12 wherein said monoaldehyde is 15.
The sporicidal composition of claim 12 wherein the pH of said 16.
The sporicidal composition of claim 12 which contains 2 to 4% 17
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Molecular Biology 
