Process for the preparation of halogenomethylketones, in particular of 1,1,1-trifluoroacetone

DETAILED DESCRIPTION What is claimes is: 1.
Process for the preparation of halogenomethylketones of the formula (I) ##STR4## in which X represents halogen, n represents 1, 2 or 3 and R represents optionally substituted C.
sub.
1 -C.
sub.
20 -alkyl, in which a nitro compound of the formula (II) ##STR5## in which X, n and R have the meaning indicated in formula (I), is treated with sodium alkoxide or potassium alkoxide in an alcohol, cooled to a temperature in the range -10.
degree.
to -100.
degree.
C.
and the mixture is then allowed to react with ozone at -10.
degree.
to -100.
degree.
C.
2.
The process of claim 1, in which in the formulae (I) and (II) X represents fluorine, chlorine and/or bromine, n represents 2 or 3, and R represents a C.
sub.
1 -C.
sub.
20 -alkyl radical which is optionally substituted by halogen atoms, aryl groups having 6 to 10 C atoms, C.
dbd.
O groups, COOR' groups where R'=C.
sub.
1 -C.
sub.
6 -alkyl and/or acetal groups of the formula (III) ##STR6## 3.
The process of claim 1, in which 1,1,1-trifluoro-2-nitropropane is employed as the compound of the formula (II) and 1,1,1-trifluoroacetone is obtained as the halogenomethylketone of the formula (I).
4.
The process of claim 1, in which 0.
8 to 1.
2 mols of sodium alkoxide or potassium alkoxide are employed per mol of nitro compound of the formula (II) and the alkoxide is added at temperatures in the range -80.
degree.
to +60.
degree.
C.
5.
The process of claim 1, in which the reaction with ozone is carried out at temperatures in the range - 50.
degree.
to -78.
degree.
C.
6.
The process of claim 1, in which ozone is added as a gas in a mixture with oxygen or dissolved in alcohol.
7.
The process of claim 1, in which 1 to 1.
2 mols of ozone per mol of the nitro compound of the formula (II) are employed.
8.
The process of claim 1, in which excess ozone is blown out after completion of the reaction.
9.
The process of claim 1, in which excess ozone is blown out after the reaction, then, if desired after addition of dimethyl sulphide, easily volatile constituents are evaporated, the residue is taken up with ether, the ethereal solution is washed with water and/or sodium chloride solution, then dried and concentrated, and the halogenomethylketone of the formula (I) prepared is isolated by distillation and/or crystallisation