Plasmid vectors including Tn904
I claim: 1. In a method including transposing a transposon by mating bacterial cells wherein the first cell contains the transposon in a first plasmid and the second cell contains a second plasmid whi... Read More
Inventors: Olsen, Ronald H.;, Assignee: Microlife Technics, Inc. (Sarasota, FL) |
Use of oxidase enzyme systems in chemiluminescent assays
What is claimed is: 1. A kit for use in a chemiluminescent assay to detect an oligonucleotide analyte, comprising the following reagents in separate containers: a) a solid support for depositing the a... Read More
Inventors: Baret, Alain;, Assignee: Canberra Industries, Inc. (Meriden, CT) |
Emergency cooling system for nuclear reactors
What we claim as new and desire to secure by United States Letters Patent is: 1. An emergency cooling system for a nuclear reactor comprising: a pressure vessel having a closure head secured in fluid-... Read More
Inventors: Frisch, deceased, Erling; Andrews, Harry N.;, Assignee: Westinghouse Electric Corporation (Pittsburgh, PA) |
Amylase determination
What is claimed is: 1. A process for determining the .alpha.-amylase content of a sample comprising the steps of adding a chromogenic oligosaccharide substrate having 4-10 glucose units and a chromoph... Read More
Inventors: Driscoll, Richard Cornelius; Gargiulo, Robert James; Giegel, Joseph L.;, Assignee: American Hospital Supply Corporation (Evanston, IL) |
Process for producing dextrose using mixed immobilized enzymes
What is claimed is: 1. A process for converting starch to dextrose comprising treating starch with alpha-amylase to obtain a partially hydrolyzed starch solution containing at least 10 percent hydroly... Read More
Inventors: Thompson, Kenneth N.; Johnson, Richard A.; Lloyd, Norman E.;, Assignee: Standard Brands Incorporated (New York, NY) |
Continuous thermal reactor system and method
What is claimed is: 1. A continuous thermal reactor comprising a reactor vessel defining an elongated upright reaction chamber having a feed inlet in the upper portion thereof for introducing a partic... Read More
Inventors: Koppelman, Edward; Murray, Robert G.;, Assignee: Koppelman; Edward (Encino, CA) |
Somatostatin analogs
What is claimed is: 1. The peptides having the structure: ##STR55## wherein: X is CH.sub.2, S, ##STR56## SO.sub.2 and [X].sub.n wherein n=0; Y is CH.sub.2, S, ##STR57## SO.sub.2 and [Y].sub.n wherein ... Read More
Inventors: Veber, Daniel F.; Holly, Frederick W.; Strachan, Robert G.; Paleveda, William J.; Nutt, Ruth F.; Hirschmann, Ralph F.;, Assignee: Merck & Co., Inc. (Rahway, NJ) |
4-Styryl-hexahydro-4-indolinols
I claim: 1. A compound of formula I, ##STR7## wherein R.sub.1 and R.sub.2 are, independently, hydrogen, fluorine, chlorine, trifluoromethyl, alkyl of 1 to 4 carbon atoms, or alkoxy of 1 to 4 carbon at... Read More
Inventors: Berthold, Richard;, Assignee: Sandoz Ltd. (Basel, CH) |
Derivatives of 1,3-benzodioxole, the preparation and use thereof
OF THE INVENTION It has been surprisingly found that the compounds of the general formula I are very active for the treatment of heart arrhythmia. Said compounds can be used for the treatment of vari... Read More
Inventors: Vanhoof, Pierre M.; Clarebout, Pierre M.;, Assignee: A. Christiaens Societe Anonyme (Brussels, BE) |
Method of preparing L-(+)-.beta.-hydroxyisobutyric acid by fermentation
OF THE INVENTION The microorganism preferably employed in carrying out the method of the present invention will be Pseudomonas aeruginosa, for example, ATCC #15523 or will be of the genus Protaminoba... Read More
Inventors: Robison, Robert S.; Doremus, Michael G.;, Assignee: E. R. Squibb & Sons, Inc. (Princeton, NJ) |
Six base oligonucleotide linkers and methods for their use
I claim: 1. A method for inserting a selected restriction site into a double stranded genetic sequence at a selected tab site comprising: treating a double stranded DNA genetic sequence with a type II... Read More
Inventors: Barany, Francis;, Assignee: Pharmacia P-L Biochemicals, Inc. (Milwaukee, WI) |
Immunoassay with chromatographic medium and labelled reagent
We claim: 1. A method of performing an immunoassay for an analyte in a sample, which method comprises providing a chromatographic medium, forming a reaction mixture containing a specific binder for th... Read More
Inventors: Edwards, John C.; Allen, Gerald J.; Martin, John K.; Summers, Malcolm R.;, Assignee: Amersham International plc. (Buckinghamshire, GB2) |
Stabilized urease composition
What is claimed is: 1. Stabilized urease composition comprising urease of a specific activity of from 25-1500 U/mg and, as a stabilizing agent, a stabilizing mixture of glutathione, ethylenediamine-te... Read More
Inventors: Schneider, Walter; Roder, Albert; Mollering, Hans; Gutmann, Ingeborg;, Assignee: Boehringer Mannheim GmbH (Mannheim-Waldhof, DE) |
Stabilized enzymic solutions for determining urea
OF THE INVENTION The stabilized enzyme solutions herein can be used in the clinical field for the determination of urea. The stabilized enzyme solutions herein can be used in conductivimetric methods... Read More
Inventors: Modrovich, Ivan E.;, Assignee: |
Non-transformed thymidine kinaseless cell line and its use for testing tumorigenic potential of genes
We claim: 1. A method for the determination of the tumorigenic or morphological transforming potential of a non-thymidine kinase (TK) gene comprising, introducing a non-TK gene and a TK gene into an a... Read More
Inventors: Hampar, Berge; Showalter, Stephen D.;, Assignee: The United States of America as represented by the Department of Health (Washington, DC) |
Article with a lyophilized immunoreactive self-adhering coating
I claim: 1. An article useful for immunological determinations which article comprises a carrier material having at least part of one surface thereof physically coated with an immunological reactive m... Read More
Inventors: Dietrich, Rolf;, Assignee: Hoffmann-La Roche Inc. (Nutley, NJ) |
Method, device and kit for measurement of tissue plasminogen activator activity
Namely, the present invention is characterized by reacting, a solid phase having bound thereto anti t-PA antibody IgG fraction having affinity to a site other than the active site of t-PA with t-PA in... Read More
Inventors: Sasamata, Miho; Ito, Katsuhisa; Katoh, Masao; Yano, Shinya; Matsumura, Eriko; Ezoe, Hisanori;, Assignee: |
Blocked cholecalciferol and dihydrotachysterol 3 derivatives
We have found that cholecalciferol and dihydrotachysterol.sub.3 and their derivatives may be metabolically blocked by the presence of a halo or O-C.sub.1-5 alkyl carbamate group in the 25-position. T... Read More
Inventors: Jones, Howard; Yang, Shu Shu; Jacobus, David P.;, Assignee: Merck & Co., Inc. (Rahway, NJ) |
4-[(Carboxyl- and sulfamyl-substituted alkyl)-amino] benzoic acids and analogs
OF THE INVENTION The compounds of the invention are new and novel 4-[(carboxyl- and sulfamyl-substituted alkyl)amino]benzoic acids and analogs which have therapeutically useful biological and pharmac... Read More
Inventors: Shepherd, Robert G.;, Assignee: American Cyanamid Company (Stamford, CT) |
Vaccine production
What is claimed is: 1. In a process for the controlled manufacture of vaccines wherein cells are grown in a glucose containing nutrient medium and infected with a virus, isocitric dehydrogenase is rel... Read More
Inventors: Miller, William J.; Spier, Raymond E.; McAleer, William J.;, Assignee: Merck & Co., Inc. (Rahway, NJ) |
Method of fermenting brewer's wort
We claim: 1. The method of preparing an alocholic beverage, comprising the steps of preparing an aqueous fermentable substrate containing fermentable carbohydrates and having a solids content in the r... Read More
Inventors: Nagodawithana, Walter T.; Cuzner, Janet M.;, Assignee: Jos. Schlitz Brewing Company (Milwaukee, WI) |
Treatment of hemorrhagic shock
I claim: 1. A method of treating shock in humans to reverse the same and elevate blood pressure which comprises intravenously administering to a patient in need thereof a therapeutically effective amo... Read More
Inventors: Laborit, Henri;, Assignee: Centre d'Etudes Experimentales et Cliniques de Physio Biologie de (Paris, FR) |
Compositions comprising alkylpolysaccharide detergent surfactant
What is claimed is: 1. A homogeneous granular detergent composition comprising: (1) from about 2% to about 30% of alkylpolysaccharide detergent surfactant having the formula RO(R.sup.1 O).sub.t Z.sub.... Read More
Inventors: Payne, Nicholas S.;, Assignee: The Procter & Gamble Company (Cincinnati, OH) |
Process for the preparation of a mixture of sucrose oxidation products and the use thereof
We claim: 1. A process for the preparation of a mixture of sucrose oxidation products which comprises a salt of sucrosetricarboxylic acid comprising reacting sucrose with oxygen in an aqueous medium i... Read More
Inventors: Leupold, Ernst I.; Schonwalder, Karl-Heinz; Fritsche-Lang, Wolfram; Schlingmann, Merten; Linkies, Adolf; Gohla, Werner; Dany, Franz-Josef;, Assignee: Hoechst Aktiengesellschaft (Frankfurt am Main, DE) |
Process for making a high density detergent composition from starting detergent ingredients
OF THE PREFERRED EMBODIMENT The present process is used in the production of low dosage detergent agglomerates directly from starting detergent ingredients rather than conventional "post-tower" deter... Read More
Inventors: Capeci, Scott W.;, Assignee: The Proctor & Gamble Co. (Cincinnati, OH) |
Aqueous alkaline composition
OF THE INVENTION In Formula I a is from 2.5 to 7, preferably from 3 to 6.5, more preferably from 3.5 to 6, most preferably, a is higher than b. In Formula II c is from 0.5 to 4, preferably from 1 to ... Read More
Inventors: Lenoir, Pierre Marie;, Assignee: The Dow Chemical Company (Midland, MI) |
Stereospecific keto reduction of bicyclooctandione-carboxylic acid esters by microorganisms
What is claimed is: 1. A process for the production of a 3.alpha.-hydroxy prostacyclin intermediate product of the formula (+)-I ##STR7## wherein A is the radical >CH--COOR, B is oxygen and R is me... Read More
Inventors: Petzoldt, Karl; Dahl, Helmut; Vorbruggen, Helmut;, Assignee: Schering Aktiengesellschaft (Berlin, DE) |
Automatic sludge extraction and washing device for use in a water treatment settling apparatus
With the above discussion in mind, it is the primary object of the present invention to provide a device for selectively automatically extracting sludge from a concentrator in a sludge bed settling ap... Read More
Inventors: Tardivel, Jacques;, Assignee: Societe Degremont (Rueil-Malmaison, FR) |
Fuel separator system
The present invention is a float actuated control to drain water from a fuel tank without loss of fuel. A float connected to a rotor in a pressurized chamber causes the rotor to move in such manner th... Read More
Inventors: Abad, Santiago; Mallay, John B.;, Assignee: Muesco, Inc. (Houston, TX) |
Methods and nucleic acid sequences for the expression of the cellulose synthase operon
The present invention provides an operon associated with the biosynthesis of cellulose, polynucleotides encoding one or more closely linked genes that code for proteins of bacterial cellulose synthase... Read More
Inventors: Ben-Bassat, Arie; Calhoon, Roger D.; Fear, Anna L.; Gelfand, David H.; Meade, James H.; Tal, Rony; Wong, Hing; Benziman, Moshe;, Assignee: Cetus Corporation (Emeryville, CA) |
Molecular Biology 
