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| Endoprosthetic device with therapeutic compound |
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| Natural tissue valve prostheses having variably complaint leaflets |
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| Device for maintaining urinary continence |
| In one aspect of the present invention, there is provided a prosthetic urethral valve assembly. The ... |
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| System and method for implanting cardiac valves |
| OF THE PREFERRED EMBODIMENTS FIG. 1 shows a stent 1 made by support means in the form of two 0.55 ... |
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| Device and methods for in vivo culturing of diverse tissue cells |
| The anatomically specific device is a living prosthesis or implant for transport and for in viva ... |
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| Apparatus and method for performing vertical banded gastroplasty |
| In accordance with the present invention, an apparatus and method which enable vertical banded ... |
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| Method for retrieving pancreatic juice utilizing and endoscopically wire-guided catheter |
| The present invention is an improved method for accurately and quickly positioning a double lumen ... |
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| Guide tube for gastrostomy tube placement |
| FIG. 1 shows a preferred guide tube 10 which is approximately 40 cm in overall length and ... |
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Composite material having absorbable and non-absorbable components for use with mammalian tissue
| Details |
Inventors: Landi, Henry P.;
Assignee: American Cyanamid Company (Stamford, CT)
Primary Examiner: Green; Randall L.
Assistant Examiner: Prebilic; Paul
Attorney, Agent or Firm: Costello, Jr.; Charles F.
The invention is a composite material of two or more biocompatible polymers, at least one of which is polytetrafluoroethylene (PTFE) and one of which is a bioabsorbable polymer. The nonabsorbable PTFE is used in the composite as a reinforcing binder. The reinforcing binder is a network of unsintered, interconnected micro-fibers which are formed, for example, by blending with a thermoplastic polymer vehicle, such as polymethylmethacrylate which is subsequently extracted. The bioabsorbable component is contained within the structure of the PTFE microfibrils. This composite is useful in the repair of mammalian tissue where tissue ingrowth and permenant support is required. |
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DETAILED DESCRIPTION I claim: 1.
A composite material for use with mammalian tissue consisting essentially of: (a) an unsintered, microfibrillar, non-absorbable biocompatible component prepared from polytetrafluoroethylene, (b) a particulate bioabsorbale filler manufactured from a polymer prepared from one or more monomers selected from the group consisting of lactides, carbonates, oxalates and lactones, and (c) a non-absorbable, biocompatible thermoplastic component manufactured from a polymer which is liquid at a temperature from about 150.
degree.
to 200.
degree.
C.
and solid at ambient temperature, and which provides additional integrity to the unsintered component.
2.
The material of claim 1 wherein the particulate bioabsorbable filler is selected from the group consisting of lactides, carbonates and lactones.
3.
The material of claim 2 wherein the lactides are selected from the group consisting of glycolide and 3,6-dimethyl-1,4-dioxan-2,5-dione; the carbonate is 1,3-dioxan-2-one; and the lactones are selected from the group consisting of e-caprolactone and 1,4-dioxan-2-one.
4.
The material of claim 3 wherein the particulates, bioabsorbable filler is manufactured from glycolide.
5.
A composite material for use with mammalian tissue comprising a first part consisting of the composite material of claim 1 in the form of a sheet, the sheet having two sides; and a second part affixed to at least one side of said sheet, the second part comprising a bioabsorbable textile reinforcement component, the bioabsorbable reinforcement component being woven or knitted, and manufactured from the same or a different polymer then the particulate bioabsorable filler of the first part.
6.
The material of claim 5 wherein the bioabsorable textile reinforcement component is selected from the group consisting of lactides, carbonates and lactones.
7.
The material of claim 6 wherein the lactides are selected from the group consisting of glycolide and 3,6-dimethyl-1,4-dioxan-2,5-dione; the carbonate is 1,3-dioxan-2-one; and the lactones are selected from the group consisting of e-caprolactone and 1,4-dioxan-2-one
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