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Defoaming composition
| Details |
Inventors: Valentine, William; Valentine, William K.;
Assignee: Valentine Enterprises, Inc. (Lawrenceville, GA)
Primary Examiner: Page; Thurman K.
Assistant Examiner: Spear; James M.
Attorney, Agent or Firm:
A defoaming or antifoaming composition comprises a free flowing granular combinate of 50 to 90 weight percent of a water soluble carbohydrate-based agglomerate selected from the group consisting of maltodextrin agglomerates, maltodextrin/dextrose co-agglomerates, dextrose agglomerates, maltodextrin/sucrose co-agglomerates, maltodextrin/fructose co-agglomerates, sucrose agglomerates, fructose agglomerates, mannitol agglomerates, sorbitol agglomerates, agglomerates of hydrolyzed cereal solids, and agglomerates of corn syrup solids and about 10 to 50 weight percent of a liquid, nonaqueous, defoaming or antifoaming composition such as simethicone, hydrocarbon-based oils or silicone oils. The composition may be combined with one or more suitable excipients and prepared as a unit dosage in the form of a compressed tablet, filled capsule, packet, or granule for various defoaming applications. |
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DETAILED DESCRIPTION OF THE INVENTION The preferred fluid, nonaqueous, antifoaming or defoaming compound prepared as a flowable granule used herein is simethicone and, more specifically, simethicone U.
S.
P.
as defined in the United States Pharmacopeia, incorporated herein by reference, which has the chemical structure: (CH.
sub.
3).
sub.
3 Si [OSi(CH.
sub.
3).
sub.
2 ].
sub.
n CH.
sub.
c +SiO.
sub.
2 and the chemical formula: Alpha(trimethylsilyl)-omega-methylpoly[oxy (dimethylsilylene)] in mixture with silicon dioxide.
Simethicone is a mixture of fully methylated linear siloxane polymers containing repeating units of the formula [-(CH.
sub.
3).
sub.
2 SiO--].
sub.
n, stablilized with trimethylsiloxy end-blocking units of the formula [(CH.
sub.
3).
sub.
3 SiO--], and silicon dioxide.
It is preferred to contain not less than 90.
5 percent and not more than 99.
0 percent of polydimethylsiloxane ([-(CH.
sub.
3).
sub.
2 SiO--]n)), and not less than 4.
0 percent and not more than 7.
0 percent of silicon dioxide.
Maltodextrins are composed of water soluble glucose polymers obtained from the reaction of starch with acid and/or enzymes in the presence of water.
The starch is hydrolyzed to produce hydrolyzate products containing sugars.
The production of starch hydrolyzates, and, in particular, low conversion starch hydrolyzates, is described in U.
S.
Pat.
Nos.
3,663,369; 3,849,194; 4,298,400; and U.
S.
Pat.
No.
Re.
30,880, the disclosures of which are hereby incorporated by reference.
The starch used for the preparation of maltodextrins can be any of a variety of commercially available starches such as maize, potato, or tapioca.
Further, the U.
S.
Food and Drug Administration defines maltodextrins, (C.
sub.
6 H.
sub.
12 O.
sub.
5).
sub.
n H.
sub.
2 O, as nonsweet nutritive saccharide polymers that consist of D-glucose units linked primarily by alpha 1-4 bonds and having a D.
E.
(total reducing sugars expressed as dextrose equivalents) of less than 20.
Maltodextrin is usually produced as a fine, white powder and is generally recognized as safe (gras) as a direct human food ingredient at levels consistent with good manufacturing practices
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Semiconductor manufacture 
