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Home Semiconductor manufacture Pediatric-effervescent-dosage-form

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 Pediatric effervescent dosage form

Details
Inventors: Wehling, Fred; Schuehle, Steve; Madamala, Navayanarao;
Assignee: Cima Labs, Inc. (Minneapolis, MN)
Primary Examiner: Waddell; Frederick E.
Assistant Examiner: Henley, III; Raymond J.
Attorney, Agent or Firm: Lerner, David, Littenberg, Krumholz & Mentlik

The present invention relates to oral effervescent dosage forms for the administrations of an intended ingredient to children, and processes for their administration.

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENT An oral dosage form according to one embodiment of the present invention is a tablet of a size and shape adapted for direct oral administration to children.
The tablet is small enough to be administered to a child.
As used in this disclosure, the term "child" refers to a person under the age of about 16 years.
The pediatric dosage forms according to this aspect of the invention are preferably useful for children under the age of about 12 years.
For children under the age of 12 years, tablets having a volume less than about 2.
0 cm.
sup.
3, and desirably less than about 1.
0 cm.
sup.
3 are preferred.
The mass of each such tablet generally should be less than about 3.
0 g and more preferably less than about 1.
5 g.
The tablet may have the shape of letters, numbers, animals, birds, cartoon characters, fish, dinosaurs, and the like.
Further, the tablet may include surface markings, cuttings, grooves, letters and or numerals for the purpose of decoration and/or identification.
The tablet is, of course, in solid form.
Preferably, the tablet is a hard compressed tablet.
It includes one or more intended ingredients, together with an effervescent disintegrating agent.
The term "intended ingredient(s)" is understood to mean an ingredient or ingredients, the ingestion of which is the reason for consuming a tablet in which that ingredient is included.
For the purposes of the present invention, an intended ingredient may include pharmaceuticals or pharmaceutically active ingredients, minerals, vitamins and dietary supplements.
Mixtures of any of the foregoing are also contemplated by the term intended ingredient.
By the term pharmaceutical or pharmaceutically active ingredient applicants mean a drug.
Pharmaceutically active ingredients may include, without limitation, antacids, analgesics, antiinflammatories, antibiotics, laxatives, anorexics, antiasthmatics, antidiuretics, antiflatuents, antimigraine agents, antispasmodics, sedatives, antihyperactives, tranquilizers, antihistamines, decongestants, betablockers, antialcoholism agents, cough suppressants, fluoride supplements, antiseptics and combinations thereof



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