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Method for improving cerebral circulation
| Details |
Inventors: Takasugi, Naoyuki; Ushijima, Mitsuyasu; Inoue, Satoshi; Hirata, Terukage;
Assignee: Wakunaga Seiyaku Kabushiki Kaisha (Osaka, JP)
Primary Examiner: Ford; John M.
Assistant Examiner: Dentz; Bernard I.
Attorney, Agent or Firm: Oblon, Fisher, Spivak, McClelland & Maier
Disclosed herein is a cerebral-circulation-metabolism-function-improving agent which contains a 2,6-diphenyl-3,7-dioxabicyclo[3.3.0]octane derivative represented by the following formula as the effective ingredient: ##STR1## wherein, each of R.sub.1, R.sub.3, R.sub.4 and R.sub.6 represents a hydrogen atom or a lower alkoxyl group; each of R.sub.2 and R.sub.5 represents a hydrogen atom, a .beta.-D-glucosyl group or a hydroxyl group; and each of R.sub.7 and R.sub.8 represents an oxygen atom or two hydrogen atoms. |
|
DETAILED DESCRIPTION This invention relates to a cerebral-circulation-metabolism-function-improving agent comprising a 2,6-diphenyl-3,7-dioxabicyclo[3.
3.
0]octane derivative represented by the following formula as the effective ingredient.
Accordingly, the cerebral-circulation-metabolism-function-improving agent according to this invention comprises a 2,6-diphenyl-3,7-dioxabicyclo[3.
3.
0]octane derivative represented by the following formula as the effective ingredient: ##STR2## wherein, each of R.
sub.
1, R.
sub.
3, R.
sub.
4 and R.
sub.
6 represents a hydrogen atom or a lower alkoxyl group; each of R.
sub.
2 and R.
sub.
5 represents a hydrogen atom, a .
beta.
-D-glucosyl group or a hydroxyl group; and each of R.
sub.
7 and R.
sub.
8 represents an oxygen atom or two hydrogen atoms.
The above physiological effect of the 2,6-diphenyl-3,7-dioxabicyclo[3.
3.
0]octane derivatives has been found unexpectedly and this invention providing a cerebral-circulation-metabolism-function-improving agent is believed to contribute greatly to the progress of therapy for various diseases caused by abnormal cerebral circulation or metabolism.
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