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Home Vasodialators Method-of-reducing-the-level-of-low-density-lipoproteins-in-the-serum-of-a-patient

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 Method of reducing the level of low density lipoproteins in the serum of a patient

Details
Inventors: Borden, Ernest C.; Shrago, Earl S.;
Assignee: Wisconsin Alumni Research Foundation (Madison, WI)
Primary Examiner: Hazel; Blondel
Assistant Examiner:
Attorney, Agent or Firm: Bremer; Howard W.

A method is described for reducing the level of low density lipoproteins in the serum of a patient by administering to the patient human fibroblast interferon.

DETAILED DESCRIPTION What is claimed is: 1.
A method for reducing the level of low density lipoproteins in the serum of a patient which comprises, administering human fibroblast interferon to the patient in an amount sufficient to lower the level of said low density lipoproteins.
2.
A method according to claim 1 wherein the interferon is administered intramuscularly.
3.
A method according to claim 1 wherein the interferon is administered in a plurality of doses over a predetermined period of time.
4.
A method according to claim 3 wherein the interferon is administered daily.
5.
A method according to claim 3 wherein the dosage level is between 3 million and 6 million units.
6.
A method for reducing the level of low density lipoproteins in the serum of a patient, which comprises administering an amount of human fibroblast interferon to the patient by intramuscular injection, in a series of doses over a predetermined period of time, sufficient to lower the level of said low density lipoproteins.
7.
A method according to claim 6 wherein the dosage level is between 1 million and 30 million units.
8.
A method for treating arteriosclerosis in a patient, comprising, administering to said patient human fibroblast interferon in an amount sufficient to lower the level of low density lipoproteins in the patient's serum without lowering the level of high density lipoproteins in the patient's serum.
9.
The method of claim 8 wherein the interferon is administered by intramuscular injection.




Description:
This invention relates to the medical arts and, more particularly, to an improved method for reducing the level of low density lipoproteins in the serum of a patient.
Serum lipids include free fatty acis, triglycerides, and cholesterol.
Cholesterol circulates primarily as a complex of lipid and proteins.
These peptides are called lipoproteins.
Lipoprotein complexes can be separated, on the basis of density, into chylomicrons, low density lipoproteins, and high density lipoproteins.
Serum cholesterol is found primarily in the form of low density and high density lipoproteins



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