2,4-disubstituted-5-cyano-1,6-dihydro-6-oxo-1-pyrimidineacetic acid aldose reductase inhibitors |
| OF THE INVENTION The compounds of formula (I) form salts with suitable therapeutically acceptable ... |
|
Circulation-active substituted 1,4-dihydropyridine-3-carboxylic acid piperazides |
| We claim: 1. A 1,4-dihydropyridine-3-carboxylic acid piperazide of formula ##STR112## in which R.... |
|
Derivatives of p-guanidinobenzoic acid |
| What we claim: 1. A derivative of p-guanidinobenzoic acid of the formula (IA): ##STR38## wherein Y ... |
|
Substituted cinnamyl-2,3-dihydrobenzofuran and analogs useful as anti-inflammatory agents |
| OF THE INVENTION A. Scope of the Invention This invention relates to novel compounds of formula (I)... |
|
Method of effecting antihistaminic, antiserotonin and antiallergic actions |
| What is claimed is: 1. Method of effecting at least one of the actions of antihistaminic, ... |
|
Quinuclidines and quinuclidinium salts as antiarrhythmic agents |
| I claim: 1. A compound of the formula I: ##STR9## wherein R.sub.1 is H or OH; R.sub.2 is H or ALK--Z... |
|
Quinuclidines, their use as medicaments and processes for their preparation |
| We claim: 1. A process for preparing 3-(2-propynyloxy)-1-azabicyclo[2,2,2,]octane, wherein a ... |
|
2-[(4-heteroaryl-1-piperazinyl)alkyl]-1,3-dioxanes and related compounds and their therapeutic utility |
| OF THE PREFERRED EMBODIMENT The compounds of this invention are useful as antipsychotic drugs and ... |
|
Pesticides |
| What is claimed is: 1. A 13.beta.-substituted compound of the formula: ##STR9## wherein: R is ... |
|
Methods for suppressing the endocrine system |
| What is claimed is: 1. A method of controlling weight gain in animals in need of such control which ... |
|
|
Plaque disclosing agent
| Details |
|
Inventors: Southard, George L.;
Assignee: Vipont Laboratories, Inc. (Fort Collins, CO)
Primary Examiner:
Assistant Examiner:
Attorney, Agent or Firm:
Salts of sanguinarine, either pure salts or a mixture of said salts precipitated from extracts of plants selected from the group consisting of Sanguinaria canadensis, Macleya cordata, Corydalis sevctvozii, C. ledebouni, Chelidonium majus, and mixtures thereon, are effective agents for disclosing plaque in the oral cavity under long wavelength ultraviolet light. |
|
DETAILED DESCRIPTION What is claimed is: 1. A method for visualizing plaque formation in the oral cavity and rendering such plaque formation visible to the naked eye under long wavelength ultraviolet light by applying to the oral cavity a sanguinarine salt selected from the group consisting of sanguinarine chloride, sanguinarine nitrate, sanguinarine sulfate, and a mixture of said salts precipitated from extracts of plants selected from the group consisting of Sanguinaria canadensis, Macleaya cordata, Corydalis sevctvozii, C. ledebouni, Chelidonium majus, and mixtures thereof. 2. The method of claim 1 wherein the sanguinarine salt is sanguinarine chloride. 3. The method of claim 1 wherein the sanguinarine salt is contained in an oral rinse. 4. The method of claim 3 wherein the sanguinarine salt is sanguinarine chloride. 5. The method of claim 3 wherein the sanguinarine salt is a mixture of benzophenanthridine salts extracted from Sanguinaria canadensis. 6. The method of claim 1 wherein the sanguinarine salt is applied in the form of a toothpaste. 7. The method of claim 6 wherein the sanguinarine salt is sanguinarine chloride. 8. The method of claim 1 wherein the sanguinarine salt is applied in the form of a toothpowder.
Description:
BACKGROUND OF THE INVENTION This invention relates to novel disclosing agents for use in the improvement of oral hygiene practices. Dental plaque is a well-organized structure which forms on tooth surfaces and restorations. It consists mainly of bacteria surrounded by a matrix derived primarily from saliva and the bacteria themselves. Plaque differs from other soft tooth deposits such as material alba and food debris in that it has a definite architecture and cannot be flushed away by rinsing with water. It is well established that dental plaque plays a major role in the etiology of periodontal diseases and caries. Although the exact manner in which plaque contributes to these disease states is not known at present, it is appreciated that effective and thorough removal of these deposits is absolutely essential for control program be established as part of the treatment plan for every dental patient
|
|