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Treatment of sexual dysfunction in certain patient groups
| Details |
Inventors: Cutler, Neal R.;
Assignee: Cutler; Neal R. (Los Angeles, CA)
Primary Examiner: Azpuru; Carlos A.
Assistant Examiner:
Attorney, Agent or Firm: Medlen & Carroll, LLP
Methods for treating specific patient groups for sexual dysfunction are provided. The methods of the present invention comprise the utilization of flosequinan and pharmaceutical compositions comprising flosequinan in patients who are free of cardiac disease, who have not been treated with a drug that causes hypotensive effects, and/or who have not been given organic nitrites or nitrates. Flosequinan and pharmaceutical compositions of flosequinan are administered to patients intranasally, orally, topically, and/or through respiratory inhalation. |
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DETAILED DESCRIPTION OF THE INVENTION The present invention relates to methods for the treatment of sexual dysfunction in males and females (including but not limited to erectile dysfunction in males) in particular treatment groups.
The methods of the present invention comprise the utilization of pharmaceutical compounds and compositions to patients who are free of symptoms of cardiac disease and who have not been treated with drugs which cause hypotensive effects, such as nitrites and nitrates.
The compositions comprise quinolines and quinolones, including derivatives thereof.
In one embodiment flosequinan is administered.
Importantly, flosequinan may potentiate the hypotensive effects of nitrates, and its administration to patients who are concurrently using organic nitrates in any form may be contraindicated.
It is contemplated that flosequinan be administered cutaneously, transurethrally, by standard injection, intracavemosally, intranasally or through respiratory inhalation, although it is not intended that the methods of the present invention be limited to the mode of administration of flosequinan.
In other embodiments, a pharmaceutical composition comprising flosequinan is administered.
It is contemplated that the pharmaceutical composition comprising flosequinan be administered cutaneously, transurethrally, by standard injection, intracavemosally, intranasally or through respiratory inhalation, although it is not intended that the methods of the present invention be limited to the mode of administration of the pharmaceutical composition.
In one embodiment, the present invention contemplates the use of compositions that are effective to induce an erection in a human male suffering from impotence of any origin, other than anatomical deficiencies (i.
e.
, lacking a penis or a significant portion thereof) that preclude an erection sufficient for vaginal penetration.
In particular, these compositions may be used to induce an erection in a male suffering from impotence caused by severe atherosclerosis, and also impotence that is neurogenic or psychogenic in origin
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