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Synthesis of 1-substituted isoquinolines |
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Sulfur-containing bis-imino carbamate compounds, pesticidal composition and use |
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Dental cream composition |
| I claim: 1. A dental cream consisting essentially of a vehicle of water and humectant and a gelling ... |
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Intracellular trapping of therapeutics or tracer agents |
| OF THE INVENTION The present invention basically involves attaching primary amine-containing ... |
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Metallo-substituted naphthalene |
| It is claimed: 1. Compounds of the formula ##STR4## wherein R is lower alkyl and R.sub.1 and R.sub.2... |
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Stabilized pharmaceutical composition and method of producing same |
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Cephalosporins |
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Bis-(aryloxycarboxylic acid) compounds |
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Ester substituted dibiguanides and non-toxic antimicrobial compositions thereof |
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Viscoelastic dentifrice composition
| Details |
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Inventors: Prencipe, Michael; Durga, Gary A.;
Assignee: Colgate Palmolive Company (Piscataway, NJ)
Primary Examiner: Rose; Shep K.
Assistant Examiner:
Attorney, Agent or Firm: Stone; Robert L., Grill; Murray M., Sullivan; Robert C.
A toothpaste or dental gel composition containing an amount of a synthetic linearly viscoelastic cross-linked polymeric thickening agent, especially a cross-linked methyl vinyl ether/maleic anhydride copolymer, effective to render the composition linearly viscoelastic, and a method of promoting oral hygiene by applying an effective amount of the composition to dental surface. |
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DETAILED DESCRIPTION We claim: 1. A linear viscoelastic dentifrice composition in the form of a toothpaste or dental gel with a pH of about 4 to about 9 comprising an orally acceptable water/humectant vehicle, an orally acceptable dental polishing agent and, in an amount effective to render the composition linearly viscoelastic, a synthetic linearly viscoelastic cross-linked polymeric thickening agent derived from a polymer containing repeating units in which one or more phosphonic acid groups are bonded to one or more carbon atoms in the polymer chain and having in a 1 wt. % aqueous solution an elastic or storage modulus G" and a viscous or loss modulus G" substantially independent of frequency in an applied frequency range of 0. 1 to 100 radians/sec, a G' minimum value of 1,000 dynes/sq. cm which varies less than 1 order of magnitude of its original value, and a ratio of G"/G' ranging from more than 0. 05 to less than 1. 2. A composition according to claim 1 containing approximately by weight, 6% to 50% of water, 20to 70% of humectant, 5 to 70% of dental polishing agent, and 0. 02% to 5% of said polymeric thickening agent containing at least about 3% of cross-linking agent. 3. A composition according to claim 1 wherein the said polymeric thickening agent is made with a cross-linking agent containing at least two ethylenically unsaturated groups or at least two groups reactive with pendant reactive groups along the polymer chain of the polymeric thickening agent. 4. A composition according to claim 3 wherein said thickening agent is made with 1,7-octadiene, 1,9-decadiene, or polyethylene glycol as cross-linking agent. 5. A composition according to claim 4 wherein said polymeric thickening agent comprises units of styrene phosphonic acid, vinyl phosphonic acid and/or vinyl phosphonyl fluoride. 6. A composition according to claim 1 wherein the polymeric thickening agent has a molecular weight of about 1,000 to about 5,000,000 and comprises units of styrene phosphonic acid, vinyl phosphonic acid and/or vinyl phosphonyl fluoride
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