Contraceptive-antivenereal disease tampon
OF PRESENT INVENTION This new invention is intended to eliminate the difficulties and objections to prior art contraceptives, The over population and pandemic venereal disease necessitates a more eff... Read More
Inventors: Donald, Jack W.;, Assignee: Donald Enterprises, Inc. (El Paso, TX) |
Fluorene derivative
OF THE INVENTION In formula (I), the phenyl group for R.sub.1 may be substituted or unsubstituted. Examples of the substituent include an alkyl group such as methyl, ethyl and butyl, and an alkoxycar... Read More
Inventors: Akasaki, Yutaka; Sato, Katsuhiro; Nukada, Katsumi;, Assignee: Fuji Xerox Co., Ltd. (Tokyo, JP) |
Use of hydroxyeicosatetraenoic acid compounds to treat ophthalmic inflammatory disorders
OF THE INVENTION As used herein, "HETE compound" or "HETE compounds" means a compound of formulas I-XI. I-III: ##STR1## wherein: X is O.sup.- M.sup.+, OR or NHR'; M.sup.+ is Na.sup.+, K.sup.+, Li.sup... Read More
Inventors: Gamache, Daniel A.;, Assignee: Alcon, Inc. (Hunenberg, CH) |
Enhancing tissue penetration of physiologically active steroidal agents with DMSC
What I claim is: 1. A method of enhancing the penetration into and across an external membrane barrier of a human or animal subject to a physiologically active steroidal agent capable of eliciting a p... Read More
Inventors: Herschler, Robert J.;, Assignee: Crown Zellerbach (San Francisco, CA) |
Percutaneous absorption accelerator and preparation containing same
Namely, the present invention provides percutaneous absorption accelerators comprising ether compounds of glycerols or polyglycerols and alcohols (hereafter simply referred to as "ether derivatives")... Read More
Inventors: Kamiya, Tetsuro; Inoue, Takeshi; Yorozu, Hidenori; Eguchi, Yasuteru; Tsujii, Kaoru;, Assignee: Kao Corporation (Tokyo, JP) |
Compositions and method comprising aminoalcohol derivatives as membrane penetration enhancers for physiological active agents
OF THE INVENTION Typical examples of compounds included in the foregoing formula I of this invention are the following: 1) 2-Ethanoylaminododecyl ethanoate 2) 2-Octanoylaminododecyl octanoate 3) 2-Oc... Read More
Inventors: Rajadhyaksha, Vithal J.;, Assignee: |
Anthranilic acid analogs
What is claimed is: 1. A method for reducing the adverse effects of smooth muscle contractions which comprises administering to a patient in need thereof, a compound of the formula: ##STR4## wherein: ... Read More
Inventors: Lennox, Joseph Richard; Antane, Schuyler Adam; Butera, John Anthony;, Assignee: American Home Products Corporation (Madison, NJ) |
Percutaneous absorption promoter, a tape plaster and a method of promoting percutaneous absorpton
OF THE INVENTION The invention will be described in detail in the following. The percutaneous absorption promoter of the invention comprises a derivative of an amino acid having the formula [1]. Exam... Read More
Inventors: Suzuki, Eiji; Okabe, Hideaki; Saito, Takanori;, Assignee: Lintec Corporation (Tokyo, JP) |
Compositions for sustained release of a gas
Among the objects of the invention, therefore, may be noted the provision of a composition that releases a concentration of chlorine dioxide sufficient to eliminate bacteria, fungi, molds, algae, prot... Read More
Inventors: Wellinghoff, Stephen T.; Barenberg, Sumner A.; Kampa, Joel J.; Barlow, Darren E.;, Assignee: Bernard Technologies, Inc. (Chicago, IL) |
Metalloproteinase inhibitors
OF THE INVENTION The present invention provides a compound of general formula (II) ##STR4## wherein X represents a --CO.sub.2 H or --CONHOH group; R.sub.1 represents the characterizing side chain of ... Read More
Inventors: Miller, Andrew; Whittaker, Mark; Beckett, Raymond Paul;, Assignee: British Biotech Pharmaceuticals Limited (GB) |
Thioether, keto-ester and alkyl phospholipids useful in treating multiple sclerosis
What is claimed is: 1. A method of treating multiple sclerosis comprising administering to a subject afflicted therewith a therapeutically effective amount of a compound of formula II: ##STR22## where... Read More
Inventors: Houlihan, William J.;, Assignee: Sandoz Ltd. (Basel, CH) |
Controlled release indomethacin
OF THE INVENTION The present invention comprises a controlled release capsule of indomethacin having a pellet which rapidly releases indomethacin and releases indomethacin in a controlled release fas... Read More
Inventors: Mehta, Atul M.;, Assignee: Norjec Development Associates, Inc. (Ramsey, NY) |
Cough/cold mixtures comprising non-sedating antihistamine drugs
OF THE INVENTION The analgesic and anti-inflammatory components in the cough/cold compositions of the present invention include the salicylic acid derivatives and acetaminophen. The salicylic acid de... Read More
Inventors: Sunshine, Abraham; Laska, Eugene M.; Siegel, Carole E.;, Assignee: Analgesic Associates (New York, NY) |
Method for controlling dust mites
What is claimed is: 1. A method for reducing the population of dust mites selected from the group consisting of Dermatophagoides pteronyssinus, Dermatophagoides farinae, Dermatophagoides microceras an... Read More
Inventors: Miller, Annette; Miller, Jeffrey D.;, Assignee: |
Pharmaceutical tablets
What we claim is: 1. A tablet consisting essentially of granules formed by wet granulation of (a) 80 to 98% by weight of a mixture of trimethoprim and/or an acid addition salt thereof and a sulfonamid... Read More
Inventors: Tan, Hong S.; Wegman, Bernardus B. M.;, Assignee: Gist-Brocades N.V. (Delft, NL) |
Controlled release compositions
We claim: 1. A controlled release composition comprising an active substance other than a prostaglandin, and a polymeric carrier therefore comprising residues which are cross-linked through urethane g... Read More
Inventors: Embry, Mostyn P.; Graham, Neil B.;, Assignee: National Research Development Corporation (London, GB2) |
Antisecretory oxamic acid esters
What is claimed is: 1. A process for treating peptic ulcer disease which comprises administering, orally or parenterally, to a mammal in need thereof an anti-secretory amount of an N-substituted lower... Read More
Inventors: Sellstedt, John H.; Guinosso, Charles J.; Shriver, David A.; Klaubert, Dieter H.;, Assignee: American Home Products Corporation (New York, NY) |
Picoline derivative useful as gastric acid secretion inhibitors
We claim: 1. A compound of formula I ##STR9## wherein each of R1, R2, R3 and R4 is in any position in the benzo part of the benzimidazole and wherein R1 denotes hydrogen or C.sub.1 -C.sub.6 -alkyl, R2... Read More
Inventors: Rainer, Georg; Figala, Volker; Kohl, Bernhard;, Assignee: Byk Gulden Lomberg Chemische Fabrik GmbH (Constance, DE) |
Antiulcer benzimidazole derivatives
We claim: 1. A compound of the formula I ##STR20## or a pharmaceutically acceptable acid addition salt thereof in which R.sub.1 and R.sub.2, which are the same or different, and each is hydrogen, alky... Read More
Inventors: Hockley, Michael H.; Titman, Roger B.;, Assignee: The Boots Company PLC (GB2) |
6-Aryl-4-hydrazinyl-s-triazin-2-ones
OF THE INVENTION Depending upon the specific substitution, compounds of Formula I above may be present in enolized or tautomeric forms. Certain of the compounds can also be obtained as hydrates or in... Read More
Inventors: Campbell, Henry F.; Scholz, Thomas H.; Douglas, George H.;, Assignee: William H. Rorer, Inc. (Fort Washington, PA) |
Fungicidally active novel substituted azolylethyl oximinoalkyl ethers
We claim: 1. A substituted azolylethyl oximinoalkyl ether of the formula ##STR33## in which R.sup.1 is phenyl optionally monosubstituted or independently disubstituted by fluorine, chlorine, bromine, ... Read More
Inventors: Stetter, Jorg; Buchel, Karl H.; Reinecke, Paul; Brandes, Wilhelm; Frohberger, Paul-Ernst;, Assignee: Bayer Aktiengesellschaft (Leverkusen, DE) |
Substituted dihydropyridine ureas
What is claimed is: 1. A compound having the formula ##STR14## and pharmaceutically acceptable salts thereof wherein X is H, C.sub.1 -C.sub.6 alkyl, CN, halo, SR or --OR wherein R is C.sub.1 -C.sub.6 ... Read More
Inventors: Ruyle, William V.; Fisher, Michael H.;, Assignee: Merck & Co., Inc. (Rahway, NJ) |
Conversion of acetonitrile to glycolonitrile and/or glycolamide
We claim: 1. The production of glycolonitrile or glycolamide by the vapor phase oxidation of acetonitrile with molecular oxygen in the absence or presence of water vapor and in the presence of a vanad... Read More
Inventors: Teller, Raymond G.; Brazdil, James F.; Glaeser, Linda C.;, Assignee: The Standard Oil Company (Cleveland, OH) |
Penicillins
The present invention relates to new penicillin compounds, to processes for their production, to pharmaceutically acceptable compositions wherein such penicillins are the active agent, and to their u... Read More
Inventors: Konig, Hans-Bodo; Schrock, Wilfried; Metzger, Karl-Georg;, Assignee: Bayer Aktiengesellschaft (DT) |
.beta.Lactam antibiotics and process for their use
What is claimed is: 1. A compound selected from the group consisting of a .beta.-lactam of the formula ##STR201## and the pharmaceutically acceptable salts thereof wherein the carbon atom designated C... Read More
Inventors: Konig, Hans-Bodo; Metzger, Karl G.; Preiss, Michael; Schrock, Wilfried;, Assignee: Bayer Aktiengesellschaft (Leverkusen, DE) |
Ergolines exhibiting protactin secretion inhibition activity
What is claimed as new and desired to be secured by Letters Patent of the United States is: 1. A compound of formula I: ##STR45## wherein R.sub.1 represents a hydrogen atom or a methyl group; R.sub.2 ... Read More
Inventors: Bernardi, Luigi; Chiodini, Laura; Mantegani, Sergio; Ruggieri, Daniela; Temperilli, Aldemio; Salvati, Patricia;, Assignee: Farmitalia Carlo Erba (Milan, IT) |
Linear polyester salts
I claim: 1. Polyester salts having the formula: ##STR4## wherein X is an alkali metal, hydrogen or a mixture of both; R is methyl or hydrogen and the average value of m is from about 3 to about 30 wit... Read More
Inventors: Tsuk, Andrew G.;, Assignee: American Home Products Corporation (New York, NY) |
Process for preparing 2-vinyl oxazolines
What is claimed is: 1. Process for preparing 2-vinyl oxazolines having the formula ##EQU10## wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4, which may be the same or different, each represents hydrogen... Read More
Inventors: Arlt, Dieter;, Assignee: Bayer Aktiengesellschaft (Leverkusen, DT) |
Virtually solvent-free crystal form of the sodium salt of Cephacetril
What is claimed is: 1. Process for the manufacture of a virtually solvent free crystal form of the sodium salt of Cephacetril, which has the following X-ray diffraction spectrum:
________________... Read More
Inventors: Urech, Jakob;, Assignee: Ciba-Geigy Corporation (Ardsley, NY) |
Method of retarding oxidation of edible fat or oil in stored food
What is claimed is: 1. A method of retarding oxidation of edible fat and oil in stored food which comprises: a. mixing said food containing said fat or oil with an amount of an antioxidant selected fr... Read More
Inventors: Sakakibara, Sakuichi; Sugisawa, Ko; Yamamoto, Masanori; Kimura, Takashi; Sekiguchi, Kazuya;, Assignee: House Food Industrial Company Limited (Higashi-Osaka, JA) |
Vasodialators 
