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| Latest patents |
Results: 871-900 of 1119
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Cryoprotective reagents in freeze-drying membranes
What is claimed is: 1. A composition for the protection of phosphoglyceride-containing biological or synthetic membranes from the disruptive effects of freezing, thawing, or freeze-drying, comprising ... Read More
Inventors: Baldeschwieler, John D.; Goodrich, Jr., Raymond P.;, Assignee: California Institute of Technology (Pasadena, CA) |
Decreasing the toxicity of an ibuprofen salt
I claim: 1. A method of decreasing the toxicity of a salt of ibuprofen by combining the salt with from one to five molar excess of a bicarbonate or carbonate. 2. claim 1 in which the molar excess of b... Read More
Inventors: Smith, Walton J.;, Assignee: |
5,6,7,8 Tetrahydroquinoline derivatives
I claim: 1. A compound of the formula ##SPC15## and the non-toxic acid addition salts thereof wherein R.sup.1 is hydrogen or alkyl of from 1 to 6 carbon atoms, R.sup.2 is hydrogen, alkyl of from 1 to ... Read More
Inventors: Curran, Adrian Charles Ward;, Assignee: John Wyeth & Brother Limited (Maidenhead, EN) |
8-Carboxylester, and 8-carbamyl derivitives of 5,6,7,8-tetrahydroquinoline
We claim: 1. A compound of formula I l ##STR11## and acid addition salts thereof with pharmaceutically acceptable acids, wherein R.sup.1, R.sup.2 and R.sup.6 are the same or different and are selected... Read More
Inventors: Curran, Adrian Charles Ward; Crossley, Roger; Hill, David George;, Assignee: John Wyeth & Brother Limited (Maidenhead, EN) |
Process for the preparation of 2,2,6,6-tetramethyl-4-oxopiperidine
What we claim is: 1. Process for the preparation of 2,2,6,6-tetramethyl-4-oxopiperidine from 2,2,4,4,6-pentamethyl-2,3,4,5-tetrahydropyrimidine (acetonine), wherein acetonine is heated a. without wate... Read More
Inventors: Orban, Ivan; Lind, Hanns; Brunetti, Heimo; Rody, Jean;, Assignee: Ciba-Geigy Corporation (Ardsley, NY) |
8-Alkyl-5-oxo-5,8-dihydro-pyrido(2,3-d)pyrimidine-6-carboxylic acids and their preparation
We claim: 1. An 8-alkyl-5-oxo-5,8-dihydro-pyrido(2,3-d)-pyrimidine-6-carboxylic acid of the formula: ##SPC24## wherein: - R' is lower alkyl radical and R is of formula ##SPC25## in which n is 0, 1, 2,... Read More
Inventors: Pesson, Marcel;, Assignee: Laboratoire Roger Bellon (Neuilly sur Seine, FR) |
O-Alkyl-S-alkyl-O-[6-alkyl- or 6-halo-pyridazin-(3)-yl]-(thiono)thiol-phosphoric acid esters
We claim: 1. An O-ethyl-S-n-propyl -O-(6-substituted-pyridazin(3)-yl)-thiono thiolphosphoric acid ester of the formula ##SPC6## in which R" is alkyl with 1 to 3 carbon atoms or halogen. 2. The compoun... Read More
Inventors: Riebel, Hans-Jochem; Rohe, Lothar; Hammann, Ingeborg; Behrenz, Wolfgang;, Assignee: Bayer Aktiengesellschaft (Leverkusen, DT) |
Process for the preparation of imidazo [1,2-a] pyridines
What is claimed is: 1. A process for the preparation of a compound having the formula: ##STR6## which comprises treating a compound having the formula: ##STR7## wherein X is a halogen, loweralkoxy or ... Read More
Inventors: Bochis, Richard J.;, Assignee: Merck & Co., Inc. (Rahway, NJ) |
Process for preparing silica-alumina
OF THE INVENTION The term "silica-alumina hydrogel" as used herein is defined as a coagulated colloid of coprecipitated, hydrated silica-alumina containing an embedded aqueous phase. The terms "acidi... Read More
Inventors: Shyr, Yen-Shin; Johnson, Marvin M.;, Assignee: Phillips Petroleum Company (Bartlesville, OK) |
Synergistic pesticidal compositions
OF THE INVENTION The fatty acids used according to the subject invention can be unsubstituted, or substituted, saturated, or unsaturated, fatty acids (or their salts), of about C7 to about C20. Speci... Read More
Inventors: Abercrombie, Kenneth D.;, Assignee: Mycogen Corporation (San Diego, CA) |
Method for improving cerebral circulation
This invention relates to a cerebral-circulation-metabolism-function-improving agent comprising a 2,6-diphenyl-3,7-dioxabicyclo[3.3.0]octane derivative represented by the following formula as the effe... Read More
Inventors: Takasugi, Naoyuki; Ushijima, Mitsuyasu; Inoue, Satoshi; Hirata, Terukage;, Assignee: Wakunaga Seiyaku Kabushiki Kaisha (Osaka, JP) |
Liquid mixing employing expanding, thinning liquid sheets
I claim: 1. A method of rapidly forming an intimate mixture of a plurality of liquids, comprising the following steps: (a) causing each of said plurality of liquids to form a continuous sheet of liqui... Read More
Inventors: Demyanovich, Robert J.;, Assignee: |
Biocidal compositions and use thereof containing a synergistic mixture of 2-bromo-2-nitropropane-1,3-diol and n-alkyl dimethyl benzyl ammonium chloride
Surprisingly, the present inventors have found that mixtures of n-alkyl (50% C.sub.14, 40% C.sub.12, 10% C.sub.16) dimethyl benzyl ammonium chloride (quat) and BNPD are especially efficacious in cont... Read More
Inventors: Whitekettle, Wilson K.; Donofrio, Deborah K.;, Assignee: Betz Laboratories, Inc. (Trevose, PA) |
Composition
OF THE INVENTION The composition according to the present invention contains a flavonoid and a processed product of a plant of the genus Pfaffia (may be designated as "Pfaffia", hereinafter). The pro... Read More
Inventors: Shibuya, Takashi; Ario, Takeshi; Fukuda, Shigeharu;, Assignee: Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (Okayama, JP) |
Para-polyfluoroisopropyl-anilino-2-oxazoline compounds, pharmaceutical compositions and method of treating hypertension
I claim: 1. A compound of the formula ##STR4## wherein X is an oxygen atom, R is alkyl having 1 to 4 carbon atoms, R.sub.1, r.sub.2 and R.sub.3 are independently hydrogen, bromine, chlorine, fluorine,... Read More
Inventors: Neustadt, Bernard R.;, Assignee: Schering Corporation (Kenilworth, NJ) |
4-Alkyl- and 4-allyl-mercapto-, -sulfinyl- and -sulfonyl-methyl-2-amino-6-N,N-dimethylcarbamoyloxy-pyrimidines, processes for producing them, compositions containing these pyrimidines, and the use thereof for controlling insect pests
What is claimed is: 1. A compound of the formula I ##STR9## wherein R.sub.1 is C.sub.1 -C.sub.4 -alkyl or allyl, R.sub.2 is hydrogen, methyl, or ethyl, R.sub.3 is methyl, ethyl or cyclopropyl, R.sub.4... Read More
Inventors: Drabek, Jozef;, Assignee: Ciba-Geigy Corporation (Ardsely, NY) |
Oral hygiene product
What is claimed is: 1. An essentially non-aqueous oral hygiene product comprising (a) at least 30% by weight of total product of a suitable alcohol; (b) a first viscosity adjuster selected from the gr... Read More
Inventors: Prussin, Samuel B.;, Assignee: Tripp; Alan R. (New York, NY); Grubstein; Samuel (New York, NY); Whelan; Eugene F. (New York, NY); Finnis; E. R. (New York, NY); Prussin; Samuel (New York, NY) |
Sulfonated bis(naphthoxy)alkanes as dental plaque barriers
I claim: 1. A sulfonated alpha, omega-bis(naphthoxy)alkane having a structure selected from the group consisting of structure (A), ##STR6## and structure (B), ##STR7## and structure (C), ##STR8## wher... Read More
Inventors: Buck, Carl J.;, Assignee: Johnson & Johnson Products Inc. (New Brunswick, NJ) |
Pharmaceutical preparations for and treatment procedures involving increasing plasma bicarbonate level
We claim: 1. A pharmaceutical oral dosage form for use in treating altered renal function or prophylactically conditioning against such alterations of an active agent capable of forming or releasing b... Read More
Inventors: Helbig, Joachim W.; Kopp, Klaus F.;, Assignee: |
Technetium-99m labeled peptides for imaging
OF THE INVENTION The present invention provides Tc-99m labeled peptides for imaging target sites within a mammalian body that comprise between 4 and 100 amino acid residues and are covalently linked ... Read More
Inventors: Dean, Richard T.; McBride, William; Buttram, Scott;, Assignee: Diatech, Inc. (Londonderry, NH) |
Metal chelators
OF THE FIGURES The invention provides chelators of diagnostically useful metals that when complexed with the metal and in a form conjugated to a targetting molecule are useful for delivering the dete... Read More
Inventors: Pollak, Alfred; Goodbody, Anne;, Assignee: Resolution Pharmaceuticals (Mississauga, CA) |
YIGSR peptide radiopharmaceutical applications
OF THE PREFERRED EMBODIMENTS OF THE INVENTION (BEST MODES FOR CARRYING OUT THE INVENTION) Using the methods of this invention, peptides with a biological-function domain comprising at least the seque... Read More
Inventors: Zamora, Paul O.;, Assignee: RhoMed Incorporated (Albuquerque, NM) |
Peptide-chelator conjugates
OF THE INVENTION The invention provides peptide-chelator conjugates that when complexed with a diagnostically useful metal are useful for imaging sites of inflammation. The peptide-chelator conjugate... Read More
Inventors: Goodbody, Anne; Pollak, Alfred;, Assignee: Resolution Pharmaceuticals Inc. (Mississauga, CA) |
Radiation-protecting agent
In view of the above-mentioned situation, the objective of the present invention consists in providing radiation-protecting agents for use in radiopharmaceuticals which prevents an active ingredient f... Read More
Inventors: Higashi, Kazuo; Washino, Komei;, Assignee: Nihon Medi-Physiscs Co., Ltd. (Hyogo-ken, JP) |
Cephalosporin derivatives
We claim: 1. A compound of the formula ##STR43## wherein R.sup.1 is hydrogen or a conventional amino-protecting group, R.sup.2 is a straight or branched chain alkyl group containing from 1 to 4 carbon... Read More
Inventors: Imae, Kiyoto; Aburaki, Shimpei; Narita, Yukio; Okumura, Jun; Naito, Takayuki;, Assignee: Bristol-Myers Company (New York, NY) |
System for whole body imaging and count profiling with a scintillation camera
An object of the present invention is to overcome the defects of the prior art, such as indicated above. Another object is to provide whole body radionuclide imaging by a stationary unmodified scintil... Read More
Inventors: Kaplan, Ervin; Cooke, Michael B. D.;, Assignee: |
N-[(optionally substituted phenylamino)carbonyl] pyridine carboxamides and insecticidal use thereof
What is claimed is: 1. A compound of the formula ##STR14## wherein each Z substituent is individually selected from the group that consists of Cl and H; each A substituent is individually selected fro... Read More
Inventors: Rigterink, Raymond H.;, Assignee: The Dow Chemical Company (Midland, MI) |
Substituted phenyl piperidines
We claim: 1. A compound characterized by the formula ##STR63## wherein n is 1 or 2, Y is OH, R.sup.1 COO--, R.sup.2 R.sup.3 NCOO-- or R.sup.4 O whereby R.sup.1 is an alkyl group having 1-5 carbon atom... Read More
Inventors: Arvidsson, Folke L.; Carlsson, Per A. E.; Hacksell, Uli A.; Hjorth, John S. M.; Lindberg, Per. L.; Nilsson, John L. G.; Sanchez, Domingo; Svensson, Nils U. E.; Wikstrom, Hakan V.;, Assignee: Astra Lakemedel Aktiebolag (Sodertalje, SE) |
Dental prophylaxis containing alkylamine fluorophosphates
What is claimed is: 1. Alkylamine fluorophosphates of the formula: ##STR3## wherein R is a linear or branched alkyl group containing 1-20 carbon atoms, R.sub.1 is hydrogen or lower alkyl containing 1-... Read More
Inventors: Soldati, Gianluigi; Eilberg, Ralph G.; Melger, Helga; Schlichting, David A.;, Assignee: Carter-Wallace, Inc. (New York, NY) |
Certain polyprenyl intermediates
OF THE INVENTION More particularly according to this invention, in general formula (I), either one of R.sup.1 and R.sup.2 is an --S(O).sub.m R.sup.3 group, and either one of A in general formula (II)... Read More
Inventors: Onishi, Takashi; Suzuki, Shigeaki; Mori, Fumio; Takigawa, Tetsuo; Fujita, Yoshiji; Mizuno, Masao; Nishida, Takashi;, Assignee: Kuraray Co., Ltd. (Kurashiki, JP) |
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Vasodialators 
