|
| Latest patents |
Results: 91-120 of 1119
|
Combating pests with substituted 3,6-diphenyl-3,4-dihydro-2H-1,3,5-oxadiazine-2,4-diones
What is claimed is: 1. An oxadiazine derivative of the formula ##STR8## in which R.sup.1 represents halogen, methyl or ethyl, R.sup.2 represents hydrogen or halogen, R.sup.3 represents hydrogen or hal... Read More
Inventors: Sirrenberg, Wilhelm; Klauke, Erich; Hammann, Ingeborg; Krehan, Ingomar; Stendel, Wilhelm;, Assignee: Bayer Aktiengesellschaft (Leverkusen, DE) |
3-(1-Imidazolyl)-derivatives of 2,3-dihydro-4H-1-benzopyran
We claim: 1. Compounds having the general formula (I) ##STR89## wherein R is C.sub.1 -C.sub.6 alkyl; n is 0, 1, 2 or 3 one of R.sub.1 and R.sub.2 is hydroxy and the other is hydrogen or C.sub.1 -C.sub... Read More
Inventors: Cozzi, Paolo; Mongelli, Nicola; Pillan, Antonio; Bergamaschi, Maria; Lovisolo, Pier P.;, Assignee: Farmitalia Carlo Erba S.p.A. (Milan, IT) |
Pharmaceutical compositions effective against coronary heart disease and hypertension
I claim: 1. A pharmaceutical composition useful in treating coronary heart disease or hypertension comprising a pharmaceutically acceptable carrier or diluent and as the active agents: (1) as componen... Read More
Inventors: Berthold, Richard;, Assignee: Sandoz Ltd. (Basel, CH) |
Composition for removing adhesives from polymeric film and process for using same
What is claimed is: 1. A process for separating an adhesive polymeric resin, from a polymeric film, where said adhesive resin is adhered to said polymeric film, said process for separating comprising ... Read More
Inventors: Schwartz, Jr., John A.;, Assignee: Partek, Inc. (Duncan, SC) |
Sustained release, and comfortable opthalmic composition and method for ocular therapy
What is claimed is: 1. An ophthalmic composition, comprising: a) at least one basic active; b) a polyanionic polymer; c) an ion exchange resin; and d) a pH adjusting agent, wherein said agent is prese... Read More
Inventors: Castillo, Ernesto J.; Sarkar, Ruma; Singh, Onkar N.; Weiner, Alan L.; Yarborough, Cody;, Assignee: Alcon Laboratories, Inc. (Fort Worth, TX) |
Bactericidal formulations for use in veterinary medicine
We claim: 1. A method of treating mycoplasmotic and bacterial infections in fowl which comprises administering drinking water to said fowl, said drinking water containing an antimycoplasmotically or a... Read More
Inventors: Metzger, Karl G.; Zeiler, Hans-Joachim; Scheer, Martin; Voege, Herbert; Grohe, Klaus;, Assignee: Bayer Aktiengesellschaft (Leverkusen, DE) |
1-(5-Amino-4H-1,2,4-triazol-3-yl)-4-substituted-piperazines
OF THE INVENTION The novel compounds of the present invention are obtainable as crystalline materials having characteristic melting points and absorption spectra. They are appreciably soluble in many... Read More
Inventors: Tomcufcik, Andrew S.; Meyer, Walter E.; Dusza, John P.;, Assignee: American Cyanamid Company (Stamford, CT) |
6-C.sub.1-4 Alkyl-7-phenyl or substituted phenyl-1,6-naphthyridine-5(6H)-ones
What is claimed is: 1. A compound of the formula ##STR19## or a pharmaceutically acceptable acid addition salt thereof, wherein R.sub.1 is C.sub.1-4 alkyl, R.sub.2 is hydrogen, C.sub.1-4 alkyl, halo, ... Read More
Inventors: Damon, II, Robert E.; Nadelson, Jeffrey;, Assignee: Sandoz, Inc. (East Hanover, NJ) |
Novel prostaglandins
OF THE INVENTION Also embraced within the scope of the present invention are the non-toxic, pharmaceutically acceptable salts of the novel compounds of the present invention when R.sub.3 is hydroxy. ... Read More
Inventors: Schaub, Robert Eugene; Weiss, Martin Joseph;, Assignee: American Cyanamid Company (Stamford, CT) |
Diolefin pheromone mimics as disruptants of sexual communication in insects
We claim: 1. Diolefin insect pheromone mimic (Z)-1,12-heptadecadiene: ##STR1## 2. Diolefin insect pheromone mimic (E)-15-methyl-1,9-heptadecadiene: ##STR2## 3. Diolefin insect pheromone mimic (Z)-15-m... Read More
Inventors: Carlson, David A.; McLaughlin, John R.;, Assignee: The United States of America as represented by the Secretary of (Washington, DC) |
Substituted phenylguanidines and method
What is claimed is: 1. A compound of the structure ##STR34## wherein R.sup.1 is lower alkyl, cycloalkylalkyl, or phenylalkyl; R.sup.2 is lower alkyl, phenyl or benzyl; and R.sup.3 is lower alkyl, cycl... Read More
Inventors: Haugwitz, Rudiger D.; Maurer, Barbara V.;, Assignee: E. R. Squibb & Sons, Inc. (Princeton, NJ) |
Cephalosporin derivatives
We claim: 1. A cephalosporin derivative of the formula ##STR153## in which n is 0 or 1, (a) the symbol R.sub.1 represents a radical of the formula ##STR154## in the syn or anti form [in which R.sub.4 ... Read More
Inventors: Farge, Daniel; Moutonnier, Claude; Le Roy, Pierre; Peyronel, Jean-Francois;, Assignee: Rhone-Poulenc Industries (FR) |
External preparations free of discoloration
What is claimed is: 1. A topical composition free of discoloration with the passage of time comprising at least 0.1 weight percent of kojic acid or a derivative thereof; at least 0.01 weight percent o... Read More
Inventors: Motono, Masahiro;, Assignee: Sansho Seiyaku Co., Ltd. (Fukuoka, JP) |
Cell-permeable protein inhibitors of calpain
The invention features methods of inhibiting a calpain (e.g., .mu.-calpain and/or m-calpain) in a cell (e.g., a eukaryotic cell). The method can be carried out, for example, by contacting the cell wit... Read More
Inventors: Potter, David A.; Skolnik, Paul;, Assignee: New England Medical Center Hospitals, Inc. (Boston, MA) |
High molecular weight piperidine derivatives as UV stabilizers
I claim: 1. A compound of the formula ##STR3## wherein X is ##STR4## R being selected from alkyl of 1-6 carbon atoms; with R.sub.1 and R.sub.2 being independently selected from the group consisting of... Read More
Inventors: Son, Pyong-Nae;, Assignee: The B. F. Goodrich Company (Akron, OH) |
N.sup.2 -naphthalenesulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof, and antithrombotic compositions and methods employing them
OF THE PREFERRED EMBODIMENTS This invention relates to a group of N.sup.2 -naphthalenesulfonyl-L-argininamides of the formula (I): ##STR2## wherein R.sub.1 is naphthyl, such as 1-naphthyl and 2-napht... Read More
Inventors: Okamoto, Shosuke; Hijikata, Akiko; Kikumoto, Ryoji; Tamao, Yoshikuni; Ohkubo, Kazuo; Tezuka, Tohru; Tonomura, Shinji;, Assignee: Mitsubishi Chemical Industries Ltd. (Tokyo, JP); Okamoto; Shosuke (BOTH OF, JP) |
Process for the production of sulfenamides
The embodiments of the invention in which an exclusive property or privilege is claimed are defined as follows: 1. In a process for the production of a sulfenamide, in which a 2-mercaptobenzothiazole ... Read More
Inventors: Cobb, Alec S.; Williams, David J.;, Assignee: Monsanto Europe S.A. (Brussels, BE) |
Intermediates for triazolobenzazepines
What is claimed: 1. A compound of the formula ##STR6## wherein X and Y are hydrogen or halogen.
Description:
DESCRIPTION OF THE INVENTION The present invention relates to triazolobenzazep... Read More
Inventors: Fryer, Rodney I.; Trybulski, Eugene J.; Walser, Armin;, Assignee: Hoffmann-La Roche Inc. (Nutley, NJ) |
Therapeutic uses of the hypervariable region of monoclonal antibody M195 and constructs thereof
OF THE INVENTION The invention provides a polypeptide which consists essentially of an amino acid sequence capable of specifically binding to the antigen to which monoclonal antibody M195 (ATCC No. H... Read More
Inventors: Scheinberg, David A.;, Assignee: Sloan-Kettering Institute for Cancer Research (New York, NY) |
Xanthene and thioxanthene derivatives, compositions thereof and treatment therewith
We claim: 1. A compound selected from the group consisting of (1) a xanthene- and thioxanthene derivatives of the formula: ##STR54## wherein X is selected from the group consisting of halogen, an alky... Read More
Inventors: Lassen, Niels; Boges, Klaus P.; Hansen, Peter B.; Buus, Jorn L. M.; Bigler, Allan J.;, Assignee: Kefalas A/S (Copenhagen-Valby, DK) |
Sulfur and silicon-containing fatty acid amides
What is claimed is: 1. A compound of the formula: ##STR17## wherein each of R.sup.1, R.sup.2 and R.sup.3 is, independently, alkyl having from 1 to 22 carbon atoms, alkenyl having from 2 to 22 carbon a... Read More
Inventors: Barcza, Sandor;, Assignee: Sandoz, Inc. (E. Hanover, NJ) |
Process of making a synthetic resin product containing a molecular inclusion compound in cyclodextrin
Under these circumstances, the present invention provides a synthetic resin product containing a compound included in cyclodextrin and a process for the production of the same. The synthetic resin pro... Read More
Inventors: Shibanai, Ichiro;, Assignee: Japan Liquid Crystal Co., Ltd. (Tokyo, JP) |
Aminoalkylethers; composition and method of use
I claim: 1. Pharmaceutical compositions for treatment of Parkinsonism which comprise as active ingredient at least one diphenylmethoxyethylamine of the general forumla ##STR16## in which R.sub.1 repre... Read More
Inventors: Gootjes, Johan;, Assignee: Gist-Brocades N.V. (NL) |
Method of protecting useful plants and formulations for use in said method
What we claim is: 1. The method of combatting fungi infections of useful plants, or of preventing such infections, which method consists of applying to the plants a fungicidally effective amount of ar... Read More
Inventors: Troiani, Nicola; Gozzo, Franco; Lorusso, Simone;, Assignee: Montedison S.p.A. (Milan, IT) |
Pharmaceutical preparation for treating hemorrhoids and anal fissures
What I claim is: 1. A pharmaceutical preparation of treating hemorrhoids and anal fissures, comprising as ingredients in the proportions by weight of about 1.4 to 0.36 parts phenol, 0.7 to 0.18 parts ... Read More
Inventors: Williams, Glenn L.;, Assignee: Stoelker; Charles V. (Philadelphia, PA) |
Alkylated amine polymers
OF THE INVENTION Compositions Preferred reaction products include the products of one or more crosslinked polymers having the formulae set forth in the Summary of the Invention, above, and one or mor... Read More
Inventors: Mandeville, III, W. Harry; Holmes-Farley, Stephen Randall;, Assignee: GelTex Pharmaceuticals Inc. (Waltham, MA) |
Imidazole derivatives of 7-[(2-amino-4-thiazolyl)-oximino] cephalosporins
OF THE INVENTION The lower alkyl groups referred to throughout this specification include straight or branched chain hydrocarbon groups containing 1 to 4 carbons, e.g., methyl, ethyl, i-propyl, t-but... Read More
Inventors: Denzel, Theodor; Breuer, Hermann;, Assignee: E. R. Squibb & Sons, Inc. (Princeton, NJ) |
Tetrahydropyridine derivative useful for inhibiting blood platelet aggregation
What is claimed is: 1. A method for inhibiting the aggregation of blood platelets in a warm-blooded animal requiring such treatment, which comprises administering to said animal an effective amount of... Read More
Inventors: Johnson, Malcolm; Mills, Stuart D.; Phillips, Paul J.;, Assignee: Imperial Chemical Industries Limited (London, GB2) |
Anti-allergic 3-(carboxycarbonyl)amino benzothiopyran-4-one derivatives, compositions, and method of use therefor
We claim: 1. A benzothiopyranone of the formula ##STR32## in which R.sub.1 represents hydrogen, lower alkyl or lower alkenyl, n represents 0, 1 or 2, Ph represents 1,2-phenylene that is mono- or poly-... Read More
Inventors: Ilvespaa, Atso; Haas, Georges;, Assignee: Ciba-Geigy Corporation (Ardsley, NY) |
Preparation of carbamates
We claim: 1. A compound of the formula ##STR3## wherein R" represents an acyl group conventionally known in the cephalosporin art, R.sub.3 represents hydrogen or methoxy, R represents hydrogen or a bl... Read More
Inventors: Roberts, Floyd E.;, Assignee: Merck & Co., Inc. (Rahway, NJ) |
|
Vasodialators 
