Amino acid solution for intravenous nutrition
OF THE PREFERRED EMBODIMENTS In the study leading to the present invention a rat whose small intestine had been surgically removed was used as a model for a post-operative patient. An investigation w... Read More
Inventors: Takami, Toru; Yonekawa, Yuriko;, Assignee: Ajinomoto Company, Incorporated (Tokyo, JP) |
Warm two tone flavored dentifrice
I claim: 1. An anhydrous heat releasing fluoride dentifrice which generates heat in the mouth enhancing the fluoride anticaries action and which effects a two tone flavor change in the oral cavity con... Read More
Inventors: Schreiber, Ronald S.; Principe, Joseph R.;, Assignee: |
Toothpaste with zeolite polishing agent
We claim: 1. In an aqueous toothpaste composition having about 15-60% by weight polishing agent, the improvement comprises said polishing agent containing at least 50% by weight of a synthetic alkali ... Read More
Inventors: Harth, Helmut; Becker, Dieter;, Assignee: Blendax-Werke R. Schneider GmbH & Co. (Mainz, DE) |
Stabilized enzymatic dentifrice containing B-D-glucose and glucose oxidase
The enzymatic dentifrice of this invention comprises an enzyme system containing an oxidizable substrate, Beta-D-glucose, and an oxidoreductase enzyme specific to such substrate, glucose oxidase, for... Read More
Inventors: Pellico, Michael A.; Montgomery, Robert E.;, Assignee: Laclede Professional Products, Inc. (Gardena, CA) |
Method and composition for prevention of plaque formation and plaque dependent diseases
I claim: 1. A method for preventing periodontitis in the oral cavity, said method comprising the steps of applying within the oral cavity, for a period of ten seconds, a stabilized aqueous solution of... Read More
Inventors: Ratcliff, Perry A.;, Assignee: |
6-Aminopenicillanic acid sulfoxide silyl esters
I claim: 1. 6-aminopenicillanic acid sulfoxide silyl esters of the formula ##STR4## wherein R is selected from the group consisting of benzyl, phenyl (amino-methylene), phenyl (benzyloxycarbamoyl-meth... Read More
Inventors: Verweij, Jan;, Assignee: Koninklijke Nederlandsche Gist-en Spiritusfabriek N.V. (Delft, NL) |
Cephalosporin esters
What I claim is: 1. A compound having the formula: ##STR12## , wherein A is phenylacetamido, phenoxyacetamido, formylamino, phthalimido, 2,2-dimethyl-3-nitroso-;b 4-phenyl-5-oxo-imidazolin-1-yl or 2-m... Read More
Inventors: Ishimaru, Toshiyasu;, Assignee: |
Process for the preparation of unsymmetrically 1,3-disubstituted nitroso ureas
What I claim is: 1. A compound of the formula: R--NH CO N (NO) CH.sub.2 --CH.sub.2 --Cl wherein (1) R is an alkyl group of from two to six carbon atoms, which may be substituted with at least one --O-... Read More
Inventors: Eisenbrand, Gerhard;, Assignee: |
Pesticidal N-[2,2-dimethyl-2,3-dihydro-7-benzofuranyl-methyl-carbamate]N-[4-] sulfide
What is claimed is: 1. N-[2,2-Dimethyl-2,3-dihydro-7-benzofuranyl methylcarbamate] N-[4-nonylphenylmethylcarbamate] sulfide. 2. An insecticidal, and nematocidal composition comprising an acceptable ca... Read More
Inventors: D'Silva, Themistocles D. J.;, Assignee: Union Carbide Corporation (New York, NY) |
(2-Oxo-pyrrolidines)-acetic hydrazides
What is claimed is: 1. (2-oxo-pyrrolidine-1) acetic hydrazide of the formula ##STR6## 2. A pharmaceutical preparation useful as a psychopharmacon and for treatment of diseases occurring in the cerebra... Read More
Inventors: Lange, Fritz-Walter; Jacobi, Haireddin; Muller, Jens;, Assignee: Chemisches Laboratorium Fritz-Walter Lange GmbH & Co KG (Gauting, DE) |
Formaldehyde stabilized coating compositions
We claim: 1. In a coating composition which comprises a film-forming material, carrier, and a 3-isothiazolone, the improvement wherein the composition further comprises a stabilizing amount of formald... Read More
Inventors: Greenfield, Stanley A.; Dupont, John A.;, Assignee: Rohm and Haas Company (Philadelphia, PA) |
Phenoxyalkanol as a stabilizer for isothiazolone concentrates
OF THE INVENTION AND THE PREFERRED EMBODIMENTS The 3-isothiazolones of interest include those disclosed in U.S. Pat. Nos. 3,523,121 and 3,761,488 as represented by the following formula: ##STR1## whe... Read More
Inventors: Willingham, Gary L.; Mattox, John R.;, Assignee: Rohm and Haas Company (Philadelphia, PA) |
Nitrogen-based stabilizers for 3-isothiazolones
I claim: 1. A method of protecting against chemical degradation an isothiazolone of the formula: ##STR4## wherein Y is (C.sub.1 -C.sub.18)alkyl or (C.sub.3 -C.sub.12)cycloalkyl each optionally substit... Read More
Inventors: Reeve, Paul F. D.;, Assignee: Rohm and Haas Company (Philadelphia, PA) |
Synergistic preservative systems for chemistry reagents
OF THE INVENTION In determining the antimicrobial system to use for critical care products, numerous factors had to be considered. Although there are many microbicides available, these antimicrobial ... Read More
Inventors: Voo, Liann; Tagliaferro, Dennis C.; Wilson, Joan B.;, Assignee: Ciba Corning Diagnostics Corp. (Medfield, MA) |
M.sub.2 receptor ligand for the treatment of neurological disorders
Muscarinic M.sub.2 receptor ligands are described which are suitable for the treatment of neurological disorders, and which may be administered with minimal side-effects. The compounds described herei... Read More
Inventors: McCabe, R. Tyler; Wilson, Bryan R.; Rhodes, Christopher A.;, Assignee: Pharmaceutical Discovery Corporation (Elmsford, NY) |
Chemical compounds
We claim: 1. A compound of the formula ##STR60## wherein p is 1 or 2; R.sup.1 is hydroxy or NR.sup.2 R.sup.3 ; R.sup.2 and R.sup.3 each are independently hydrogen, (lower)alkyl, (lower)alkenyl, (lower... Read More
Inventors: Crenshaw, Ronnie R.; Algieri, Aldo A.;, Assignee: Bristol-Myers Company (New York, NY) |
Quinoline derivatives microbicides containing these compounds, and their use for controlling bacteria and fungi
We claim: 1. A quinoline derivative of the formula ##STR7## where R.sup.1 is hydrogen or methyl, R.sup.2 is hydrogen or halogen, R.sup.3 is hydrogen, methyl, halogen or nitro, R.sup.4 is hydrogen, hal... Read More
Inventors: Hamprecht, Gerhard; Theobald, Hans; Spiegler, Wolfgang; Richarz, Winfried; Ammermann, Eberhard; Pommer, Ernst-Heinrich;, Assignee: BASF Aktiengesellschaft (Ludwigshafen, DE) |
Azolyl substituted aralkyl compounds and pesticidal use thereof
I claim: 1. A compound of formula (I): ##STR15## wherein R.sup.1 is hydrogen or halogen, R.sup.2 is methyl or ethyl, X and Y are independently selected from halogen, haloalkyl, haloalkoxy, alkyl and a... Read More
Inventors: Bushell, Michael J.;, Assignee: Imperial Chemical Industries PLC (London, GB2) |
3-Substituted thio-6-amido-7-oxo-1-azabicyclo[3.2.0]-hept-2-ene-2-carboxylic acid s-oxides
OF THE INVENTION The compounds of the present invention (I, above) are conveniently prepared by the following scheme: ##STR4## Relative to the above reaction scheme, it is recognized that the sulfoxi... Read More
Inventors: Christensen, Burton G.; Guthikonda, Ravindra N.; Johnston, David B. R.; Schmitt, Susan M.;, Assignee: Merck & Co., Inc. (Rahway, NJ) |
Heterobicyclic keto- and amino-acids, esters and amides
OF THE INVENTION The compounds of the invention may be prepared by a number of different routes including the following: (1) Compounds of the formula (I) wherein R.sup.2 is hydrogen or alkyl having f... Read More
Inventors: Barnish, Ian T.; Cross, Peter E.;, Assignee: Pfizer Inc. (New York, NY) |
Alkoxy anilides and pharmaceutical compositions
What we claim is: 1. A compound of the formula ##SPC12## wherein: m is O or an integer of 1 to 5; q is 3; R is hydrogen or lower alkyl of 1 to 6 carbon atoms in the chain; R.sub.1 is lower alkyl of 1 ... Read More
Inventors: Malen, Charles; Roger, Pierre; Poignant, Jean-Claude; Pascaud, Xavier;, Assignee: Science Union et Cie, Societe Francaise de Recherche Medical (Suresnes, FR) |
1-Oxacephems
I claim: 1. The compound of the formula: ##STR59## wherein R.sup.7 is selected from the group consisting of methyl and hydroxyl. 2. The compound of claim 1, which is the 3-methyl-4-carboxy-7S-amino-1-... Read More
Inventors: Wolfe, Saul;, Assignee: Queen's University at Kingston (Kingston, CA) |
6-Loweralkoxy or loweralkylthio-3-cephem-4-carboxylic acids
What is claimed is: 1. The compound having the following formula: ##STR7## wherein X is oxygen or sulfur, R' is lower alkyl of 1-5 carbon atoms, R" is hydrogen, or ##STR8## wherein R.sub.10 is hydroge... Read More
Inventors: Christensen, Burton G.; Ratcliffe, Ronald W.;, Assignee: Merck & Co., Inc. (Rahway, NJ) |
7-(Substituted methyl)-3-(substituted thio)-cephalosporins, derivatives and pharmaceutical compositions containing them
OF THE INVENTION The following U.S. Patents and co-pending, commonly assigned U.S. Patent Applications are incorporated herein by reference for the subject matter which they disclose as it relates to... Read More
Inventors: Beattie, Thomas R.; Cama, Lovji D.; Christensen, Burton G.; Dininno, Frank P.;, Assignee: Merck & Co., Inc. (NJ) |
Multi-conductor insulation stripping apparatus
OF THE PREFERRED EMBODIMENT A preferred embodiment of the present invention will now be described with reference to the drawing. Noting FIG. 1, the cable stripping apparatus, referred to generally by... Read More
Inventors: Farmer, Cloyd C.;, Assignee: Brunswick Corporation (Skokie, IL) |
1-Oxadethiacepham compounds
OF THE INVENTION The first gist of this invention is based on the discovery that the starting material II, vide infra, cyclizes by the attack of oxygen from the reverse side of the ring juncture and ... Read More
Inventors: Yoshioka, Mitsuru; Shoichiro, Uyeo; Hamashima, Yoshio; Kikkawa, Ikuo; Tsuji, Teruji; Nagata, Wataru;, Assignee: Shionogi & Co., Ltd. (Osaka, JP) |
Water-soluble monoazo dyestuff containing a phenylene diazo component
We claim: 1. A water-soluble monoazo dyestuff of the formula ##STR14## wherein R is alkoxy of 1 to 4 carbon atoms, alkyl of 1 to 4 carbon atoms, chlorine or bromine, R' is hydrogen, lower alkoxy of 1 ... Read More
Inventors: Schlafer, Ludwig; Hoyer, Ernst;, Assignee: Hoechst Aktiengesellschaft (Frankfurt am Main, DT) |
Phenylbenzoate 1-cyanoalkoxy compounds
We claim: 1. A compound of formula: ##STR6## wherein R is an alkyl of from one to twelve carbon atoms, and R' is an alkyl of from one to thirteen carbon atoms. 2. The compound of claim 1 wherein R is ... Read More
Inventors: Eidman, Kirk F.; Walba, David M.;, Assignee: University Patents, Inc. (Westport, CT) |
Thermochromic esters
We claim: 1. A liquid crystalline phase comprising at least two components, wherein at least one component is a compound of the formula I ##STR7## wherein R.sup.1 is a normal or branched alkyl residue... Read More
Inventors: Sage, Ian C.; Clemitson, Robert W.;, Assignee: Merck Patent Gesellschaft mit beschrankter Haftung (Darmstadt, DE) |
Pyrimidine compound
OF THE INVENTION The compound of the present invention as represented by the above general formula can be prepared by a common method used in synthesizing phenylpyrimidine compounds. For example, it ... Read More
Inventors: Shibata, Toshihiro; Kimura, Masaki; Kurosawa, Norio;, Assignee: Adeka Argus Chemical Co., Ltd. (Tokyo, JP) |
Vasodialators 
