Blends of absorbable polyoxaamides
OF THE INVENTION The aliphatic polyoxaamides (which also includes polyoxaesteramides that are within the scope of the present invention) of the present invention are the reaction product of 1) an ali... Read More
Inventors: Bezwada, Rao S.; Jamiolkowski, Dennis D.;, Assignee: Ethicon, Inc. (Somerville, NJ) |
Absorbable polyoxaesters containing amines and/ or amido groups
OF THE INVENTION The aliphatic polyoxaesters of the present invention are the reaction product of a non-dioxycarboxylic acid and an aliphatic polyoxycarboxylic acid and at least one of the following ... Read More
Inventors: Jamiolkowski, Dennis D.; Bezwada, Rao S.;, Assignee: Ethicon, Inc. (Somerville, NJ) |
Chemically modified hyaluronic acid preparation and method of recovery thereof from animal tissues
OF THE INVENTION The present invention is based on our discovery that HA can be chemically modified in situ before it is extracted from animal tissues by treatment of the tissue with a substance that... Read More
Inventors: Balazs, Endre A.; Leshchiner, Adolf; Leshchiner, Adelya; Band, Philip;, Assignee: Biomatrix, Inc. (Ridgefield, NJ) |
Colored cosmetic compositions
We claim: 1. A cosmetic composition comprising: (a) a pigment formed by incorporating a solvated dye into a resin that is transparent to light and acts as a solvent for the dye, the pigment being grou... Read More
Inventors: Calvo, Luis C.; Peters, David W.;, Assignee: Estee Lauder, Inc. (New York, NY) |
Materials and method for preparing dialysis solutions containing bicarbonate ions
This invention provides, at a relatively low cost, improved material formulations and an improved method for preparing bicarbonate comprising solutions for dialysis use. The materials include, in each... Read More
Inventors: Veltman, Preston L.;, Assignee: |
Dialysis solution mixing system
Accordingly to the present invention, there is provided a system and a method for preparing dialysis solution from water and shipping drums containing dry chemicals within a protective, water proof li... Read More
Inventors: Harm, William H.; Fuller, Larry E.; Caine, Earnest R.; Cracauer, Raymond F.; Cosentino, Louis C.; Martinez, F. Jesus;, Assignee: Minntech Corporation (Minneapolis, MN) |
Dry chemical mix system for hemodialysis
Dialysate solution used in hemodialysis therapy is generally formed by mixing together controlled proportions of liquid dialysate concentrate and water using a "proportioning system." A first type of ... Read More
Inventors: Mills, Gary N.; Willock, Charles B.;, Assignee: CD Medical Inc. (Miami Lakes, FL) |
Sodium bicarbonate dialysate
What is claimed is: 1. A sodium bicarbonate dialysate comprising an electrolyte composition A composed mainly of sodium chloride and containing no sodium bicarbonate and an electrolyte granule B conta... Read More
Inventors: Itoh, Nobuo;, Assignee: Nikkiso Co., Ltd. (Tokyo, JP); Towa Pharmaceutical Co., Ltd. (Kadoma, JP) |
Dry dialysate composition
The problems described above are solved by an automated hemodialysis-filtration system comprising a supply-regulated blood pump, a hemofilter, a hemodialyzer, and an inverted drip chamber, wherein the... Read More
Inventors: Ahmad, Suhail; Cole, James J.; Jensen, William;, Assignee: University of Washington (Seattle, WA) |
Device for the preparation of a solution for medical use
OF THE PREFERRED EMBODIMENTS This installation is organized around a device consisting of a set of five cartridges, respectively referenced 1 to 5, arranged in parallel and each of which contains a s... Read More
Inventors: Lascombes, Jean-Jacques;, Assignee: |
Method of producing an artificial kidney perfusion component for bicarbonate dialysis and the artificial kidney perfusion component
After an intensive research undertaken to overcome the above-mentioned disadvantages of the prior arts, the inventor of the present invention discovered that intrinsically pure electrolyte compounds c... Read More
Inventors: Aoyama, Hideyuki; Mukai, Hisao; Murakami, Kazuya;, Assignee: Tomita Pharmaceutical Co., Ltd. (Naruto, JP) |
Pharmaceutical preparations containing platinum complexes/phosphonic acid liquid and processes for their use
What is claimed is: 1. A pharmaceutical preparation comprising at least 0.5% by weight of a pharmaceutical vehicle and also comprising a platinum complex or a salt, with a pharmacologically acceptable... Read More
Inventors: Keppler, Bernhard; Blum, Helmut;, Assignee: Henkel Kommanditgesellschaft auf Aktien (Deusseldorf, DE) |
Cephalosporin analogues and antimicrobial compositions
What we claim is: 1. The syn isomer of a compound of the formula: ##STR20## wherein R.sup.3 is furyl; A is lower alkoxyiminomethylene; R.sup.2 is carboxy; and pharmaceutically acceptable salts thereof... Read More
Inventors: Hashimoto, Misashi; Hemmi, Keiji; Aratari, Matsuhiko; Takeno, Hidekazu; Hagiwara, Daijiro;, Assignee: Fujisawa Pharmaceutical Co., Ltd. (Osaka, JP) |
Aqueous protein solutions stable to denaturation
What is claimed is: 1. A sterile aqueous solution of a water soluble biologically active protein, which solution has a pH between 6.8 and 8 and additionally has admixed therewith from 2 to 500 ppm of ... Read More
Inventors: Thurow, Horst;, Assignee: Hoechst Aktiengesellschaft (Frankfurt am Main, DE) |
Cyclic analogs of atrial natriuretic peptides
We claim: 1. A peptide compound having natriuretic, diuretic and/or vasodilator activity in mammals, which has the formula: X.sub.1 A.sub.y X.sub.2 -AA.sub.8 -AA.sub.9 -AA.sub.10 -AA.sub.11 -AA.sub.12... Read More
Inventors: Lewicki, John A.; Scarborough, Robert M.; Johnson, Lorin K.;, Assignee: California Biotechnology Inc. (Mountain View, CA) |
Method for inhibiting blood vessel blockage using octapeptide compositions
In general, the present invention is directed to a method of inhibiting blood vessel blockage in a mammal, e.g., a human, by administering to a patient a therapeutically effective amount of an octapep... Read More
Inventors: Ramwell, Peter W.; Braquet, Pierre;, Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (Paris, FR) |
Novel treatment for acute organic cerebral syndromes (strokes)
I claim: 1. A method for treating individuals suffering from the acute phases of the organic cerebral syndrome due to arterial occlusion which comprises administering to such individual patients effec... Read More
Inventors: Silvestrini, Bruno;, Assignee: |
Novel naphthalene derivative
What we claim is: 1. A naphthalene derivative of the formula: ##STR55## wherein Ring A is an unsubstituted benzene ring, a benzene ring having 1 -3 substituent(s) selected from an alkoxy group and a h... Read More
Inventors: Iwasaki, Tameo; Takashima, Kohki;, Assignee: Tanabe Seiyaku Co., Ltd. (Osaku, JP) |
Growth-inhibitory factor obtained from human brain
What is claimed is: 1. A pure protein having a growth-inhibitory activity extracted from the human brain having a molecular weight of about 5000 (according to the SDS-polyacrylamide gel electrophoreti... Read More
Inventors: Uchida, Yoko;, Assignee: |
Substituted aminopyrimidines as antihypertensives
What is claimed is: 1. A compound having the formula: ##STR16## wherein R.sup.1 is alkyl of 1-6 carbon atoms, perfluoroalkyl of 1-6 carbon atoms, cycloalkyl of 3-7 carbon atoms, fluoro, chloro, or bro... Read More
Inventors: Sarantakis, Dimitri; Bicksler, James J.; Ellingboe, John W.; Nikaido, Madelene;, Assignee: American Home Products Corporation (Madison, NJ) |
2-Aryl substituted heterocyclic compounds as antiallergic and antiinflammatory agents
What is claimed is: 1. A compound having the formula ##STR34## wherein ##STR35## with the proviso that when Y is --S--, R.sup.1 is --(CH.sub.2).sub.n ##STR36## n is 0-5; R.sup.2 is hydrogen, loweralky... Read More
Inventors: Musser, John H.; Bender, Reinhold H. W.; Kreft, III, Anthony F.;, Assignee: American Home Products Corporation (New York, NY) |
Aryl-N-hydroxyureas as inhibitors of 5-lipoxygenase and anto-arteriosclerotic agents
OF THE INVENTION The starting heterocyclic intermediates of the formula ##STR18## are prepared according to standard literature procedures. For example, 4-(1'-hydroxyethyl)-5-methyl-2-phenyloxazoles ... Read More
Inventors: Malamas, Michael S.; Gunawan, Iwan;, Assignee: American Home Products Corporation (Madison, NJ) |
Oxazolidinedione hypoglycemic agents
OF THE INVENTION The compounds of formula I wherein the dotted line represents no bond are prepared by two procedures. The first procedure or process comprises the removal of a triphenylmethyl moiety... Read More
Inventors: Dow, Robert L.; Hulin, Bernard; Clark, David A.;, Assignee: Pfizer Inc. (New York, NY) |
Imidazoline derivatives, salts thereof and their use as pesticides
What is claimed is: 1. An imidazoline compound of formula (I): ##STR16## wherein Ar is selected from a phenyl or a mono-, di- or tri-substituted phenyl radical in which the substituents may be the sam... Read More
Inventors: Black, Malcolm H.; Frenkel, Alexander D.; Roberts, Peter T.;, Assignee: Burroughs Wellcome Co. (Research Triangle Park, NC) |
Pesticidal anilinomethylimidazolines
We claim: 1. A method for preventing pests of the Order Acarina from producing viable eggs which comprises applying to the pest or the pest's environment an effective amount of a compound of formula (... Read More
Inventors: Copp, Frederick C.; Roberts, Peter T.; Frenkel, Alexander D.; Collard, David;, Assignee: Burroughs Wellcome Co. (Research Triangle Park, NC) |
Amidines, preparation process and therapeutical application thereof
We claim: 1. Compounds of the formula: ##STR35## in which: R.sub.1 and R.sub.2 represent each a hydrogen atom or form together a divalent ethylene radical, R.sub.3 represents a methyl group or a metho... Read More
Inventors: Coquelet, Claude; Battais, Elisabeth; Bonne, Claude; Sincholle, Daniel;, Assignee: Laboratoires Chauvin-Blache (Montpellier, FR) |
3-aryloxy-3-substituted propanamines
OF THE INVENTION In the above formula, the term C.sub.1 -C.sub.4 alkyl represents a straight or branched alkyl chain bearing from one to four carbon atoms. Typical C.sub.1 -C.sub.4 alkyl groups inclu... Read More
Inventors: Robertson, David W.; Wong, David T.; Krushinski, Jr., Joseph H.;, Assignee: Eli Lilly and Company (Indianapolis, IN) |
Use of .alpha..sub.1C specific compounds to treat benign prostatic hyperlasia
OF THE INVENTION The present invention provides a method of treating benign prostatic hyperplasia in a subject which comprises administering to the subject a therapeutically effective amount of a com... Read More
Inventors: Gluchowski, Charles; Forray, Carlos C.; Chiu, George; Branchek, Theresa A.; Wetzel, John M.; Hartig, Paul R.;, Assignee: Synaptic Pharmaceutical Corporation (Paramus, NJ) |
Use of .alpha.-1C specific compounds to treat benign prostatic hyperplasia
OF THE INVENTION The present invention provides a method of treating benign prostatic hyperplasia in a subject which comprises administering to the subject a therapeutically effective amount of a com... Read More
Inventors: Gluchowski, Charles; Forray, Carlos C.; Chiu, George; Branchek, Theresa A.; Wetzel, John M.; Hartig, Paul R.;, Assignee: Synaptic Pharmaceutical Corporation (Paramus, NJ) |
Tricyclic substituted hexahydrobenz [e]isoindole alpha-1 adrenergic antagonists
OF THE INVENTION As used throughout this specification and the appended claims, the following terms have the meaning specified. The terms "lower alkyl" or "alkyl" as used herein refer to straight or ... Read More
Inventors: Meyer, Michael D.; Altenbach, Robert J.; Basha, Fatima Z.; Carroll, William A.; Drizin, Irene; Elmore, Steven W.; Kerwin, Jr., James F.; Lebold, Suzanne A.; Lee, Edmund L.; Sippy, Kevin B.; Tietje, Karin R.; Wendt, Michael D.;, Assignee: Abbott Laboratories (Abbott Park, IL) |
Vasodialators 
