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| Method for chemoprevention of prostate cancer |
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| Food additive composition |
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| Method for chemoprevention of prostate cancer |
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| Placental alkaline phosphatase to control diabetes |
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| Process for producing malt alcoholic drink |
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| Composition for the treatment of cutaneous mycosis |
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Methods for stabilizing ingredients within cosmetics, personal care and household products
| Details |
Inventors: Chaudhuri, Ratan; Puccetti, Germain; Marchio, Francois; Lascu, Zoia;
Assignee: Merck Patent GmbH (Darmstadt, DE)
Primary Examiner: Dodson; Shelley A.
Assistant Examiner:
Attorney, Agent or Firm: Millen, White, Zelano & Branigan PC
The present invention relates to methods and compositions for using photostabilizer compounds for stabilizing formulation ingredients, like flavors, fragrances, colors, antioxidants, polymers, within cosmetics, personal care and household products, against degradation from sun light, heat and air oxidation resulting in improvement in storage stability, viscosity, and maintenance of color of the formulated products. |
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DETAILED DESCRIPTION What is claimed is: 1.
A method of stabilizing at least one photosensitive poly-unsaturated and/or aromatic compound which is either a color compound, antioxidant, a fragrance compound, a flavor compound or a combination thereof, said method comprising combining at least one compound of formulae ii, ii' and/or i'' with said at least one photosensitive poly-unsaturated and/or aromatic compound in a ratio within a range of 10:1 to 1:2 based on total weight percent of the one or more compounds of formulae ii, ii' and/or i'' to the total weight percent of the one or more photosensitive poly-unsaturated and/or aromatic compounds, ##STR00008## wherein each R.
sub.
ii is independently linear or branched C.
sub.
1 to C.
sub.
8 alkyl; R.
sub.
ii1 is --C(O)CH.
sub.
3, --CO.
sub.
2R.
sub.
ii3, --C(O)NH.
sub.
2, --C(O)N(R.
sub.
ii4).
sub.
2, or --CN; X is O, NH or N-alkyl; R.
sub.
ii2 is linear or branched C.
sub.
1 to C.
sub.
20 alkyl; R.
sub.
ii3 is linear or branched C.
sub.
1 to C.
sub.
20 alkyl; each R.
sub.
ii4 is independently hydrogen or linear or branched C.
sub.
1 to C.
sub.
8 alkyl; R.
sub.
ii'1 is --C(O)CH.
sub.
3, --CO.
sub.
2R.
sub.
ii'3, --C(O)NH.
sub.
2, --C(O)N(R.
sub.
ii'4).
sub.
2, or --CN; R.
sub.
ii'2 is linear or branched C.
sub.
1 to C.
sub.
30 alkyl; R.
sub.
ii'3 is linear or branched C.
sub.
1 to C.
sub.
20 alkyl; each R.
sub.
ii'4 is independently hydrogen or linear or branched C.
sub.
1 to C.
sub.
8 alkyl; R.
sub.
ii'5 is linear or branched C.
sub.
1 C.
sub.
8 alkyl or hydrogen; R.
sub.
ii'6 is linear or branched C.
sub.
1 C.
sub.
8 alkyl; each R.
sub.
i'' is independently linear or branched C.
sub.
1 to C.
sub.
8 alkyl, or linear or branched C.
sub.
1 to C.
sub.
8 alkoxy; or one R.
sub.
i'' is H and the other R.
sub.
i'' is linear or branched C.
sub.
1 to C.
sub.
8 alkyl, or linear or branched C.
sub.
1 to C.
sub.
8 alkoxy, R.
sub.
i''1 is COCH.
sub.
3, CO.
sub.
2R.
sub.
i''5, CONH.
sub.
2, CONH(R.
sub.
i''6).
sub.
2, CN, COX(CH.
sub.
2)n-N--(R.
sub.
i''2)(R.
sub.
i''4)(R.
sub.
i''3), or the quaternized salt form of the formula COX(CH.
sub.
2)n-N--(R.
sub.
i''2)(R.
sub.
i''4)(R.
sub
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