Methods for the inhibition of neointima formation

DETAILED DESCRIPTION Compositions and methods are provided for preventing restenosis through local delivery of anti-restenotic agents.
In one embodiment of the invention, the localized delivery is effected through the use of a drug delivery stent.
One stent of interest is a; channeled stent comprising a matrix, where the matrix has entrapped the anti-restenotic agent.
The matrix resides within the channels, and stent and matrix are encased with a gel covalently bound to the stent surface, which prevents loss of the matrix during transport and implantation of the stent.