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 Microcapsules containing suspensions of biologically active compounds and ultraviolet protectant

Details
Inventors: Scher, Herbert B.; Chen, Jin Ling;
Assignee: Zeneca Limited (GB)
Primary Examiner: Levy; Neil S.
Assistant Examiner:
Attorney, Agent or Firm: Ackerman; Joel G.

Microcapsules containing a biologically active material which is sensitive to ultraviolet light are prepared which contain an ultraviolet light protectant selected from titanium dioxide, zinc oxide and mixtures thereof, suspended and thoroughly dispersed in a liquid.

DETAILED DESCRIPTION OF THE INVENTION In general, the invention uses the process described in the parent application hereof, application Ser.
No.
08/354,409, filed Dec.
24, 1994, to produce microcapsules.
This technique will be described herein.
In the parent application, the technique was utilized for producing microcapsules containing a suspension of a biologically active solid in a liquid.
In the present invention, the technique is utilized for preparing a suspension of a solid ultraviolet light protectant material in a liquid which comprises biologically active material.
By "comprises", it is meant that the biologically active material may also be in the form of a solid suspended in the liquid, or may be dissolved in the liquid, or may itself constitute the liquid in which the ultraviolet light protectant is suspended.
In another embodiment, the microcapsule may contain a suspension of a solid biologically active compound in a liquid which comprises a second biologically active compound (for example, the second biologically active compound is the liquid or is dissolved in the liquid), and which also contains a thoroughly dispersed particulate ultraviolet light protectant.
The biologically active material which is to be protected in this invention may be any of those known to be subject to degradation or decomposition by ultraviolet light.
Notable among such compounds are the pyrethroids and pyrethrins.
Many of the pyrethroids are known to be susceptible to degradation by ultraviolet light including permethrin, cypermethrin, deltamethrin, fenvalerate, cyfluthrin, resmethrin, allethrin, etofenprox, and lambda-cyhalothrin.
Other biologically active materials which are known to be susceptible to degradation or decomposition by ultraviolet light include the herbicides trifluralin, ioxynil and napropamide, the insecticides pirimiphos-methyl and chlorpyrifos and the fungicide azoxystrobin.
Microcapsules of this invention may contain two or more ultraviolet light sensitive biologically active materials



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