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Non-corrosive sterilant composition
| Details |
Inventors: Richter, Francis L.; Reinhardt, Duane J.; Swart, Sally K.;
Assignee: Ecolab Inc. (St. Paul, MN)
Primary Examiner: Pak; John
Assistant Examiner:
Attorney, Agent or Firm: Merchant & Gould P.C.
A non-corrosive, liquid, aqueous sterilant composition (as a concentrate or ready-to-use solution), which may be provided in two parts which are mixed prior to application, may comprise a peracid (in an equilibrium solution with an underlying carboxylic acid or mixtures of alkyl carboxylic acids and peroxide), inorganic buffering agent, and water. It has been found that the use of this simplified system, even in the absence of additional components which have been thought to be desirable for sterilants used on metal parts (e.g., copper and brass corrosion inhibitors, chelating agents, anti-corrosive agents) display excellent performance and that these additional components are not necessary, and that the presence of these additional materials at least complicates disposal of the spent solutions and could complicate compatibility of the sterilant solutions with some polymeric materials, especially where organic materials are used as the additional components, which organic materials may interact with, dissolve or solubilize in the polymeric materials. |
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DETAILED DESCRIPTION A non-corrosive, liquid, aqueous sterilant composition (as a concentrate or ready-to-use solution), which may be provided in two parts which are mixed prior to application, may comprise a peracid (in an equilibrium solution with an underlying carboxylic acid or mixtures of alkyl carboxylic acids and peroxide), inorganic buffering agent, and water.
It has been found that the use of this simplified system provides excellent sterilization ability, even in the absence of additional components which have been thought to be desirable for sterilants used on metal parts (e.
g.
, copper and brass corrosion inhibitors, chelating agents, anti-corrosive agents) which have been found to not be necessary.
The presence of these additional materials at least complicates disposal of the spent solutions and could complicate compatibility of the sterilant solutions with some polymeric materials, especially where organic materials are used as the additional components, which organic materials may interact with, dissolve or solubilize in the polymeric materials.
The concentration of the components has shown itself to be important in providing non-corrosive effects towards a wide variety of structural materials in medical devices and yet providing effective sterilization effects against spores and bacteria, including tuberculosis bacteria in an acceptable amount of time.
An aqueous sterilant use solution according to the present invention may comprise a solution having a pH of from 5.
0 to 7.
0 comprising from 100 to 10,000 parts per million of a peroxy acid and 30 to 5000 parts per million of buffering agent, preferably without any organic anticorrosive agents.
The aqueous sterilant solution may, for example, comprise from 100 to 10,000 parts per million of a peroxy acid, 30 to 5000 parts per million of buffering agent and a catalytically effective amount of a catalyst for peroxygenation of a carboxylic acid by hydrogen peroxide.
The aqueous sterilant solution may consist essentially of a solution having a pH of from 5
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Weight Loss and Supplements 
