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 Skin smoothing compositions containing hydroxyacids and methods for using same

Details
Inventors: Jacobs, Michelle Matathia; Lentini, Peter J.;
Assignee: E-L Management Corp (New York, NY)
Primary Examiner: Venkat; Jyothsna
Assistant Examiner:
Attorney, Agent or Firm: Lowney, Esq.; Karen A.

Disclosed are skin smoothing compositions containing hydroxyacids or hydroxyacid derivatives, a polymeric film-forming agent, a physical exfoliant, and a pharmaceutically acceptable carrier. Also disclosed are methods for using the skin smoothing compositions to improve the smoothness of human skin.

DETAILED DESCRIPTION OF THE INVENTION In accordance with the present invention there are provided skin smoothing compositions comprising: (a) from about 0.
5 to about 15.
0 weight percent of a hydroxyacid; (b) from about 0.
1 to about 5.
0 weight percent of a polymeric film-forming agent; (c) from about 5.
0 to about 30.
0 weight percent of a physical exfoliant; and (c) from about 50.
0 to about 94.
4 weight percent of a pharmaceutically acceptable carrier.
The compositions of this invention comprise from about 0.
5 to about 15.
0 weight percent, preferably from about 1.
0 to about 3.
0 weight percent, most preferably about 2.
5 weight percent of a hydroxyacid.
The term "hydroxyacid" for purposes of the present invention encompasses alpha-hydroxyacids and beta-hydroxyacids in their free acid form, as well as covalent derivatives thereof.
Suitable hydroxyacids include, but are not limited to, alpha-hydroxyacids such as lactic acid, glycolic acid, citric acid, alpha-hydroxyoctanoic acid, alpha-hydroxydecanoic acid, alpha-hydroxylauric acid, tartaric acid, glucoronic acid, galactouronic acid, alpha-hydroxybutyric acid, alpha-hydroxyisobutyric acid, malic acid, mandelic acid, mucic acid, pyruvic acid and tartronic acid, especially lactic acid, glycolic acid, citric acid, mandelic acid, alpha-hydroxyoctanoic acid, alpha-hydroxydecanoic acid, and alpha-hydroxylauric acid, most especially lactic acid and citric acid; beta-hydroxyacids such as salicylic acid; and mixtures thereof especially mixtures of lactic acid, alpha-hydroxyoctanoic acid, alpha-hydroxydecanoic acid and alpha-hydroxylauric acid.
Suitable covalent derivatives of hydroxyacids include esters, amides and lactones thereof, and mixtures thereof.
The compositions of the present invention additionally comprise from about 0.
1 to about 5.
0 weight percent, preferably from about 0.
2 to about 1.
0 weight percent, most preferably about 0.
3 weight percent of a polymeric film forming agent.
In a preferred embodiment of the invention the polymeric film forming agent is a polymeric quaternium ammonium salt



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