 Fungicidal compositions containing N-acetonylbenzamides |
| We claim: 1. A fungicidal composition comprising synergistic fungicidally effective amounts of (a) ... |
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| Methods for stabilizing ingredients within cosmetics, personal care and household products |
| What is claimed is: 1. A method of stabilizing at least one photosensitive poly-unsaturated and/or ... |
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| Topical anti-inflammatory composition and method |
| The present invention is a composition and method for topically treating inflammation caused by a ... |
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| Pharmaceutical compositions and preparations thereof |
| OF THE INVENTION The invention and its various aspects will now be described hereunder. Examples 1 ... |
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| Pain reliever and method of use |
| OF THE PREFERRED EMBODIMENTS Capsaicin is trans-8-methyl-N-vanillyl-5 nonenamide, a naturally ... |
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| Burn and wound ointment |
| We claim: 1. An ointment for the treatment of burns and wounds in mammals, which comprises:
___... |
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| Dietary supplement containing saw palmetto, pumpkin seed, and nettle root |
| OF THE PREFERRED EMBODIMENTS This invention is directed to a dietary supplement for use in ... |
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| Method and apparatus for preparing a dairy product |
| The residence time of the starter culture in the pre-incubator is preferably from about 10 to ... |
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| 1,3,5 trisubstituted pyrazole compounds for treatment of inflammation |
| What is claimed is: 1. A compound of Formula I ##STR7## wherein R.sup.1 is alkylsulfonyl or ... |
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Skin whitener composition containing mercaptodextran
| Details |
Inventors: Dornoff, Jeffrey M.;
Assignee: Amway Corporation (MI)
Primary Examiner: Pace; Thurman K.
Assistant Examiner: Seidleck; Brian K.
Attorney, Agent or Firm: Brinks Hofer Gilson & Lione, Nichols; G. Peter
A skin whitening composition includes mercaptodextran. The composition can be topically applied to the human skin and can include one or more whitening agents in combination with mercaptodextran to achieve enhanced whitening effect. A method of whitening human skin includes topically applying to the skin mercaptodextran in an amount and for a period of time sufficient to visibly whiten the skin. The method includes incorporating mercaptodextran with known whitening agents and applying to the skin in an amount and for a period of time sufficient to visibly whiten the skin. |
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DETAILED DESCRIPTION OF THE INVENTION In accordance with the present invention, a skin whitener composition is provided and comprises mercaptodextran as an active ingredient.
In the whitener composition according to the present invention, the amount of mercaptodextran to be used can not be absolutely specified because it varies according to the form of the preparation.
It is, however, generally used in an amount from about 0.
01% to about 50%, more generally from about 0.
01% to about 10%.
Preferably the mercaptodextran is used in an amount from about 0.
05% to about 2%, more preferably from about 0.
1% to about 1% based on the whole weight of the whitener composition.
Mercaptodextran is a polythiol that can be synthesized by thiolating a dextran compound using for example N-acetylhomocysteine thiolactone.
The dextrans may have any suitable molecular weight from about 500 to 500,000.
The mercaptodextrans useful in the present invention can be prepared according to the method set forth in Eldjarn, L.
& E.
Jellum: Organomercurial-polysaccharide, a chromatographic material for the separation and isolation of SH-proteins; Acta Chem.
Scand.
, 17:2610-21 (1963), and/or Jellum, E.
, J.
Aaseth & L.
Eldjarn: Mercaptodextran, a metal chelating and disulphide-reducing polythiol of high molecular weight; Biochem.
Pharmacol.
, 22:1179-88 (1973), both which are incorporated herein by reference.
Alternatively, it is believed that the mercaptodextran can be made by polymerizing the dextran with a sulfur derivative such as mercaptosuccinic acid.
In any event, it is not presently believed that the method of manufacturing is critical to the practice of the present invention.
Thus, the mercaptodextran can be prepared by any suitable method.
As noted above, since it is believed that the dextran can have any molecular weight from about 500 to about 500,000, the resulting mercaptodextran may also have any suitable molecular weight from about 500 to about 500,000 such that the mercaptodextran exhibits tyrosinase inhibition
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