Polycationic peptide coatings and methods of coating implantable medical devices
L-arginine, also known as 2-amino-5-guanidinovaleric acid, is an amino acid having a formula NH═C(NH2)—NH—CH2—CH2—CH2—CH(NH2)—COOH. Polymers and/or oligomer... Read More
Inventors: Pacetti, Stephen D.; Michal, Eugene T; Hossainy, Syed F A; Ding, Ni; Roorda, Wouter E;, Assignee: Advanced Cardiovascular Systems, Inc. (Santa Clara, CA) |
Fatty analogues for the treatment of diabetes
OF THE INVENTION The present invention discloses that modified fatty a The present invention discloses that modified fatty acid analogous at non-cytotoxic concentrations can be used for the treatment... Read More
Inventors: Berge, Rolf;, Assignee: Thia Medica AS (NO) |
Biphenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia
What is claimed is: 1. A compound of the formula: ##STR17## D is oxygen, sulfur, or nitrogen; E is carbon or nitrogen; Y is a bond, methylene, C(O), or CH(OH); R.sup.1 is alkyl containing 1 to 12 carb... Read More
Inventors: Malamas, Michael S.; McDevitt, Robert E.; Adebayo, Folake O.;, Assignee: American Home Products Corporation (Madison, NJ) |
Protein hydrolyzates, process for producing the same and drinks and foods containing the protein hydrolyzates
1. A method of manufacturing protein hydrolysate at a recovery rate of 60% or higher, the method comprising the steps of: carrying out hydrolysis of a protein starting material to a rate of hydrolysis... Read More
Inventors: Hayasawa, Hirotoshi; Tamura, Yoshitaka; Miyakawa, Hiroshi; Shichino, Toshikazu; Kawaguchi, Yasushi; Kanehara, Hirokatsu;, Assignee: Morinaga Milk Industry Co., Ltd. (Tokyo, JP) |
Alcohol free mouthwash
OF THE INVENTION The substantially non-alcoholic mouthwash compositions of the present invention are useful in the germ kill of microorganisms responsible for plaque, gingivitis and other oral diseas... Read More
Inventors: Chaudhari, Atma; Scheurer, Heinrich; Pan, Pauline; Volpe, Frank;, Assignee: Warner-Lambert Company (Morris Plains, NJ) |
Non-toxic disinfectant containing a isopropyl alcohol and sesame oil composition with lemon oil and menthol
OF THE PREFERRED EMBODIMENT Disinfectants and delivery systems have been developed aimed at destroying various pathogenic organisms. The chemical and biological effectiveness of such disinfectants ar... Read More
Inventors: Viamonte, Jr., Manuel;, Assignee: |
Stable, cosmetically acceptable topical gel formulation and method of treatment for acne
What is claimed is: 1. A stable, cosmetically elegant gel formulation for the topical treatment of acne in humans comprising an effective amount of a compound selected from the group consisting of tho... Read More
Inventors: Ritter, Lawrence;, Assignee: American Cyanamid Company (Wayne, NJ) |
Sunscreen compositions
OF THE INVENTION Now it has been discovered that exceptional aesthetics (e.g. light skinfeel), stability and rich viscosity (non-watery) properties are achieved by combination of an organic sunscreen... Read More
Inventors: Mohammadi, Fatemeh;, Assignee: Elizabeth Arden Company, Division of Conopco, Inc. (New York, NY) |
Compositions of chemically modified insulin
OF THE INVENTION The design, synthesis and characterization of various representative PEG-insulin conjugates have been optimized for pulmonary delivery to the lung. Although the preparation of PEG-in... Read More
Inventors: Patton, John S.; Kuo, Mei-Chang; Harris, J. Milton; Leach, Chester; Perkins, Kimberly; Bueche, Blaine;, Assignee: Nektar Therapeutics (San Carlos, CA) |
Higher alcohol toxicants effective against insects
We claim: 1. A method of controlling mites which comprises applying to a human or animal host in need of such control, an effective toxic amount of at least one monohydric alcohol of 4-18 carbon atoms... Read More
Inventors: Lover, Myron J.; Singer, Arnold J.; Lynch, Donald M.; Rhodes, III, William E.;, Assignee: Block Drug Company Inc. (Jersey City, NJ) |
Anti-lice treatment compositions
OF THE INVENTION The present invention relates to active compositions developed for controlling the infestation of the hair by human head lice. The active compositions disclosed herein may be incorpo... Read More
Inventors: Cardin, Caroline W.; Peter, David W.; Markham, Clint A.;, Assignee: The Procter & Gamble Company (Cincinnati, OH) |
Fragrance compositions having antimicrobial activity
OF THE PREFERRED EMBODIMENT The fragrances that exhibit antimicrobial effects according to the present invention are those that satisfy the following criteria: 1. the fragrances contain between 3 and... Read More
Inventors: Nakatsu, Tetsuo; Van Loveren, Augustinus G.; Kang, Raphael K. L.; Cilia, Alba T.;, Assignee: |
Sunscreen having disappearing color indicator
OF THE INVENTION In the present specification, the terms "emulsion," "formulation" and "composition" can be used interchangeably. The emulsion of the present invention contains one or more oil-solubl... Read More
Inventors: Fowler, Kevin C.;, Assignee: Schering-Plough HealthCare Products, Inc. (Memphis, TN) |
Durable multi-component antibiotic formulation for topical use
OF THE PREFERRED EMBODIMENTS This invention is directed to methods and formulations for the treatment or prevention of infections on mammalian tissues such as skin. However, prior to discussing this ... Read More
Inventors: Askill, Ian N.;, Assignee: MedLogic Global Limited (Cheshire, GB) |
Composition of multipurpose high functional alkaline solution composition, preparation thereof, and for the use of nonspecific immunostimulator
OF THE INVENTION The present invention contemplates an NIS based on an alkaline solution composition. This composition comprises sodium metasilicate, borax, sodium thiosulfate, potassium carbonate, r... Read More
Inventors: Choi, Soo-Il; Choi, Hyun-Suk; Jeon, Kyung-Soo; Yoo, Byung-Woo; Park, Yong-Ho;, Assignee: BARODON-S.F. Corp. (Kyunggi-Do, KR) |
Galactomannan products and compositions containing the same
We claim: 1. An emulsified isolated fenugreek galactomannan having at least 50 repeating units of mannose and galactose in a ratio of between 0.5-1.0 and 1.8-1.0, and consisting essentially of isolate... Read More
Inventors: Garti, Nissim; Aserin, Abraham; Madar, Zecharia; Sternheim, Boaz;, Assignee: Yissum Research Development Company (IL) |
Pharmaceutical composition for diabetic nephropathy
OF THE INVENTION Accordingly, the present invention provides a synergistic pharmaceutical composition for the treatment of diabetic nephropathy in subjects, said composition comprising an effective a... Read More
Inventors: Salimath, Paramahans Veerayya; Sambaiah, Kari; Nandini, Chikunda Dattatreya;, Assignee: Council of Scientific and Industrial Research (New Delhi, IN) |
Method of preparing inorganic polymeric water complexes and products so produced
The subject matter the applicants claim as their invention is: 1. A method of producing inorganic polymeric water complexes stable throughout the pH range from 0 to 14 which comprises reacting in an a... Read More
Inventors: McCoy, Charles R.; Defalco, Frank G.;, Assignee: |
Stable salicylic acid and peroxide containing skin and hair cleanser composition
OF THE INVENTION An aqueous skin care composition comprising: a. 0.5 to 5% peroxides; b. 0.5 to 5% salicylic acid; c. 0.1 to 50% adjunct surfactant; d. 0.1 to 5% phosphate ester, selected from one of... Read More
Inventors: Burke, John Jerome; Gorczyca, Joanne Paula;, Assignee: BASF Corporation (Mount Olive, NJ) |
Vitaminized air freshner and room deodorizer
I claim: 1. A vitamin containing room deodorizer spray non-film forming fluid composition for changing the smell within the confines of a room and for intra-nasal delivery of droplets of soluble vitam... Read More
Inventors: Mettler, Leo;, Assignee: |
Nasal spray compositions exhibiting increased retention in the nasal cavity
OF THE INVENTION The aqueous nasal spray compositions of the present invention comprise a medicament in an aqueous carrier containing a water soluble polymer selected from the group consisting of pol... Read More
Inventors: Haslwanter, Joseph A.; Rencher, William F.;, Assignee: Schering-Plough Healthcare Products, Inc. (Memphis, TN) |
Herbal based nasal spray
OF THE PREFERRED EMBODIMENT Since the instant invention has a two-fold purpose, namely an antihistamine and a decongestant, the detailed description of the composition will be first described by the ... Read More
Inventors: Wiersma, Jack G.;, Assignee: Nouveau Technologies, Inc. (Tequesta, FL) |
Pharmaceutical compositions and methods for managing skin conditions
OF THE PREFERRED EMBODIMENTS A formulation for the prevention, treatment, and management of skin conditions, such as seborrheic dermatitis, psoriasis, folliculitis, rosacea, perioral dermatitis, acne... Read More
Inventors: Murad, Howard;, Assignee: |
Liquid spray dispenser and method
A liquid dispenser for medical applications comprises, according to the present invention, a pressurized liquid container, a nozzle, and a conduit or flow guide connected to the container and the nozz... Read More
Inventors: Gold, Scott; Mizzi, John V.;, Assignee: Pincgold LLC (New York, NY) |
Calcium mupirocin non-aqueous nasal spray for otitis media or for recurrent acute bacterial sinusitis
What is claimed is: 1. A non-aqueous sprayable formulation suitable for nasal delivery of a medicament comprising: (a) an amphiphilic agent selected from the group consisting of: mono-glycerides; phos... Read More
Inventors: Hatton, Anthony Guy; Scott, Hugh; Hilton, Jane Elizabeth;, Assignee: Smithkline Beecham Corporation (Philadelphia, PA) |
Acidic buffered nasal spray
We initially tested various preparations within the scope of the claims to confirm in vitro that they killed rhinovirus. We mixed rhinovirus with the claimed preparation and monitored the rhinovirus ... Read More
Inventors: Gern, James E.; Mosser, Anne G.;, Assignee: Wisconsin Alumni Research Foundation (Madison, WI) |
D-alanine racemase mutants of mycobacteria and uses therefore
OF THE INVENTION The present invention is directed to D-alanine racemase mutants of mycobacterial species. The D-alanine racemase gene (alrA) is involved in the synthesis of D-alanine, a basic compon... Read More
Inventors: Barletta, Raul G.; Barletta-Chacon, Ofelia;, Assignee: Board of Regents University of Nebraska-Lincoln (Lincoln, NE) |
Histidine containing nutriceutical compositions
What is claimed is: 1. A nutriceutical composition comprising: (a) 100 to 1500 mg of a cyto-protective agent selected from the group consisting of at least one of D-histidine, L-histidine, a racemic m... Read More
Inventors: Thomas, Peter G.; Wade, A. Michael;, Assignee: Cytos Pharmaceuticals, LLC (Durham, NC) |
Ingestibles possessing intrinsic color change
What is claimed is: 1. A solid ingestible comprising: a microcrystalline polydiacetylene polymer having a transition temperature in the range of about -10 to 200.degree. C., wherein said polymer is ph... Read More
Inventors: Ribi, Hans O.;, Assignee: Segan Industries, Inc. (Burlingame, CA) |
Process for synthesis of 1R,2R,5R-2-hydroxy-6-oxo-7-oxabicyclo[3.2.1]-octane
OF THE INVENTION AND PREFERRED EMBODIMENTS The process of the present invention can be readily understood by reference to the following Flow Chart A. ##STR6## In this flow scheme, the starting materi... Read More
Inventors: Mills, Sander G.; Volante, Ralph P.; Shinkai, Ichiro;, Assignee: Merck & Co., Inc. (Rahway, NJ) |