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Latest patents Results: 151-180 of 4665
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Inulin infused fruit and method of preparation
OF THE INVENTION The present invention relates to dried food product infused with inulin characterized by high inulin levels and to methods of their preparation and use. Each of the product component... Read More
Inventors: Froseth, Barrie R.; Creedon, Sean W.;, Assignee: General Mills, Inc. (Minneapoli, MN)
Non-corrosive sterilant composition
A non-corrosive, liquid, aqueous sterilant composition (as a concentrate or ready-to-use solution), which may be provided in two parts which are mixed prior to application, may comprise a peracid (in ... Read More
Inventors: Richter, Francis L.; Reinhardt, Duane J.; Swart, Sally K.;, Assignee: Ecolab Inc. (St. Paul, MN)
Hydantoin therapeutic agents
OF THE INVENTION In accordance with the process employed for obtaining the novel dextrorotatory compounds of this invention, a corresponding racemic or dl-spiro-hydantoin having the same general stru... Read More
Inventors: Sarges, Reinhard;, Assignee: Pfizer Inc. (New York, NY)
Phthalazin-4-ylacetic acid derivatives
What is claimed is: 1. A phthalazin-4-ylacetic acid derivative of the formula: ##STR20## wherein R.sup.1 is a hydroxy or benzyloxy radical, or a C.sub.1-4 -alkoxy radical optionally bearing an N-morph... Read More
Inventors: Brittain, David R.; Wood, Robin;, Assignee: Imperial Chemical Industries Limited (London, GB2)
Food or dietetic substances having an alveolar structure and process of preparing same
What is claimed is: 1. A process for preparing a dietetic bakery product having an aveolar structure which consists essentially of the steps of (a) kneading a mixture consisting essentially of at leas... Read More
Inventors: Mendy, Francois; Blain, Sylvain; Domer, Roland;, Assignee: Roussel Uclaf (Paris, FR)
Method of inhibiting aldose reductase activity
What is claimed is: 1. A method for treating diabetic complications in mammals comprising administering an effective amount of spiro-(fluoren-9,4'-imidazolidine)-2',5'-dione or pharmaceutically accept... Read More
Inventors: York, Jr., Billie M.;, Assignee: Alcon Laboratories, Inc. (Fort Worth, TX)
Rhodanine derivatives, process for their preparation, and aldose reductase inhibitor containing the rhodanine derivatives as active ingredient
We claim: 1. An aldose reductase inhibitor containing, as an active ingredient, 3-carboxymethyl-5-(2-methylcinnamylidene)rhodanine or non-toxic salts of an acid thereof. 2. A rhodanine derivative whic... Read More
Inventors: Tanouchi, Tadao; Kawamura, Masanori; Ajima, Akio; Mohri, Tetsuya; Hayashi, Masaki; Terashima, Hiroshi; Hirata, Fumio; Morimura, Takeshi;, Assignee: Ono Pharmaceutical Co., Ltd. (Osaka, JP)
N-naphthoylglycine derivatives
OF THE INVENTION The compounds of this invention, represented by formula I, can exist in rotameric forms. More explictly, mesomerism imparts a partial double bond character to the carbon-nitrogen bon... Read More
Inventors: Sestanj, Kazimir; Abraham, Nedumparambil A.; Bellini, Francesco; Treasurywala, Adi;, Assignee: Ayerst, McKenna & Harrison, Inc. (Montreal, CA)
Antidiabetic 3,4,5-trihydroxypiperidines
What is claimed is: 1. A compound of the formula ##STR264## in which R.sub.1 is C.sub.5 -C.sub.30 alkyl, C.sub.2 -C.sub.18 alkenyl, C.sub.2 -C.sub.18 alkinyl, C.sub.3 -C.sub.8 cycloalkyl, C.sub.3 -C.s... Read More
Inventors: Junge, Bodo; Krause, Hans P.; Muller, Lutz; Puls, Walter;, Assignee: Bayer Aktiengesellschaft (Leverkusen, DE)
N-substituted pseudo-aminosugars, their production and use
What is claimed is: 1. A compound of the formula: ##STR35## wherein A is a chain hydrocarbon group having 1 to 10 carbon atoms which may be substituted by hydroxyl, phenoxy, thienyl, furyl, pyridyl, c... Read More
Inventors: Horii, Satoshi; Kameda, Yukihiko; Fukase, Hiroshi;, Assignee: Takeda Chemical Industries, Inc. (Osaka, JP)
Thiolactam-n-acetic acid derivatives
We claim: 1. A compound of the formula: ##STR11## wherein, R.sup.1 and R.sup.2 are, the same or different, hydrogen, a halogen, a lower alkyl, a cycloalkyl having 3.degree.-7 carbon atoms, a lower alk... Read More
Inventors: Meguro, Kanji; Ikeda, Hitoshi; Yamamoto, Yujiro;, Assignee: Takeda Chemical Industries, Ltd. (Osaka, JP); Senju Pharmaceutical Co., Ltd. (Osaka, JP)
Rhodanine derivatives, process for their preparation, and aldose reductase inhibitor containing the rhodanine derivatives as active ingredient
I claim: 1. A rhodanine derivative represented by the general formula: ##STR13## wherein R.sup.11 represents a hydrogen atom; R.sup.22 represents: (1) a 5- to 10-membered mono or bicyclic heterocyclic... Read More
Inventors: Tanouchi, Tadao; Kawamura, Masanori; Ajima, Akio; Mohri, Tetsuya; Hayashi, Masaki; Terashima, Hiroshi; Hirata, Fumio; Morimura, Takeshi;, Assignee: Ono Pharmaceutical Co., Ltd. (Osaka, JP)
Fuel supply systems
We claim: 1. A liquid fuel pump arrangement for delivering liquid fuel to an engine comprising a liquid-ring pump including a motor-driven bladed impeller rotor which is located eccentrically within a... Read More
Inventors: Goddard, John; Taylor, Peter;, Assignee: Plessey Overseas Limited (Ilford, GB2)
Heterocyclic oxophthalazinyl acetic acids
OF THE INVENTION The numbering system of the compounds of formula I is as shown: ##STR5## The term "(C.sub.1 -C.sub.4)alkyl" whenever used in the definitions of R.sub.1 to R.sub.4 denotes saturated m... Read More
Inventors: Larson, Eric R.; Mylari, Banavara L.;, Assignee: Pfizer Inc. (New York, NY)
Spiro-isoquinoline-pyrrolidines and analogs thereof useful as aldose reductase inhibitors
We claim: 1. The compounds of structural formula (I) ##STR5## wherein R.sup.1 and R.sup.2 are independently hydrogen, alkyl containining 1 to 6 carbon atoms, halogen, lower alkoxy containing 1 to 6 ca... Read More
Inventors: Malamas, Michael S.;, Assignee: American Home Products Corporation (New York, NY)
Novel alpha-glucosidase inhibitor, pradimicin Q
OF THE INVENTION One aspect of the present invention provides the compound pradimicin Q and its pharmaceutically acceptable base salts. "Pharmaceutically acceptable base salts" includes, but is not l... Read More
Inventors: Sawada, Yosuke; Ueki, Tomokazu; Tsuno, Takashi; Oki, Toshikazu;, Assignee: Bristol-Myers Squibb Company (New York, NY)
.alpha.-glucosidase inhibitors
What is claimed is: 1. 1-deoxy nojirimycin derivatives of the formula ##STR5## and the pharmaceutically acceptable acid addition salts thereof wherein n is zero, 1 or 2 and R is a glycosyl moiety, whi... Read More
Inventors: Ducep, Jean-Bernard; Danzin, Charles;, Assignee: Merrell Dow Pharmaceuticals Inc. (Cincinnati, OH)
Oxetanones
OF THE INVENTION As used herein, the term "alkyl" denotes a straight or branched chain alkyl containing the number of carbon atoms designated. Examples of C.sub.1 -C.sub.17 -alkyls are methyl, ethyl,... Read More
Inventors: Barbier, Pierre; Schneider, Fernand; Widmer, Ulrich;, Assignee: Hoffmann-La Roche Inc. (Nutley, NJ)
Process for the preparation of .alpha.-glucosidase inhibitor, pradimicin Q
OF THE INVENTION One aspect of the present invention provides the compound pradimicin Q and its pharmaceutically acceptable base salts. "Pharmaceutically acceptable base salts" includes, but is not l... Read More
Inventors: Sawada, Yosuke; Ueki, Tomokazu; Tsuno, Takashi; Oki, Toshikazu;, Assignee: Bristol-Myers Squibb Company (New York, NY)
Pyridopyrimidine derivatives, pharmaceutical compositions containing them and process for preparing same
We claim: 1. A compound of the Formula (I) ##STR7## wherein R is a C.sub.1 to C.sub.12 alkyl group substituted by C.sub.1 to C.sub.4 alkoxycarbonyl, a C.sub.3 to C.sub.9 cycloalkyl group, an adamantyl... Read More
Inventors: Hermecz, Istvan; Knoll, Jozsef; Vasvari nee Debreczy, Lelle; Gyires, Klara; Sipos, Judit; Horvath, Agnes; Tardos, Laszlo; Blaogh, Maria;, Assignee: Chinoin Gyogyszer- Es Vegyeszeti Termekek Gyara Rt. (Budapest, HU)
Inhibitor of absorption of digestion product of food and drink
OF THE INVENTION The following examples are to explain this invention in detail, not to limit its scope. EXAMPLE 1 Acqueous Enteric Material--Flocculant (a) Granules of sodium polyacrylate with an ap... Read More
Inventors: Ochi, Shigeo;, Assignee: Hanabusa Patent Office (Tokyo, JP)
Hydantoin derivatives for treating complications of diabetes
OF PREFERRED EMBODIMENTS The invention will now be further explained with reference to Manufacturing Examples of the compounds and salts, Pharmacological Test Examples as well as Prescriptional Examp... Read More
Inventors: Kurono, Masayasu; Kondo, Yasuaki; Yamaguchi, Takuji; Miura, Kenji; Usui, Toshinao; Terada, Naofumi; Asano, Kyoichi; Mizuno, Kuniharu; Matsubara, Akira; Kato, Noriaki; Sawai, Kiichi; Unno, Ryoichi; Ozawa, Hiroshi; Fukushima, Masato;, Assignee: Sanwa Kagaku Kenkyusho Co., Ltd. (Aichi, JP)
Oral composition
OF THE INVENTION Although the present invention is described below with reference to examples, the present invention is not limited to the examples. Example 1 GS dry leaves of India growth were extra... Read More
Inventors: Ueno, Gaku;, Assignee: Dai-Nippon Meiji Sugar Co., Ltd. (Tokyo, JP)
Formulation for administration of steroid compounds
OF THE INVENTION By 5.beta. steroid is meant .alpha. ET, .beta. ET, and ED. In addition certain alkylated derivatives of these 5.beta. steroids are also included in this definition. For example 16- a... Read More
Inventors: Rubinfeld, Joseph; Vida, Julius A.; Bradlow, H. Leon; Fineman, Elliott L.;, Assignee: Supergen, Inc. (San Ramon, CA)
Methods and reagents for discovering and using mammalian melanocortin receptor agonists and antagonists to modulate feeding behavior in animals
OF THE PREFERRED EMBODIMENTS The term "melanocortin receptor" as used herein refers to proteins having the biological activity of any of the disclosed melanocortin receptors, including the MC-1 (SEQ ... Read More
Inventors: Cone, Roger D.; Fan, Wei; Boston, Bruce A.; Kesterton, Robert A.; Lu, Dongsi; Chen, Wenbiao;, Assignee: Oregon Health Sciences University (Portland, OR)
Methods for regulating levels of zinc, cadmium and calcium in humans and for diagnosing, or screening for the risk of developing, diseases associated with abnormal levels of cadmium, zinc and calcium in body fluids and tissues
OF THE INVENTION It is known that stallions have low fertility (e.g. unsuccessful equine in vitro fertilization (1)) and approximately ⅓ the incidence of cancer mortality compared to humans or... Read More
Inventors: Woods, Gordon L.;, Assignee: CancEr2 Inc. (Moscow, ID)
Compositions and method for targeted controlled delivery of active ingredients and sensory markers onto hair, skin, and fabric
The present invention relates to a targeted controlled release composition in the form of nano spheres for targeted controlled delivery of active ingredients and sensory markers onto hair, skin, and f... Read More
Inventors: Shefer, Adi; Shefer, Samuel David;, Assignee: Salvona, LLC (Dayton, NJ)
Geldanamycin derivatives and antitumor drug
OF THE PREFERRED EMBODIMENTS The Geldanamycin derivatives having the formula (I) can be produced by reacting Geldanamycin with an amine having the formula ##STR8## wherein R.sup.7 and R.sup.8 respect... Read More
Inventors: Sasaki, Kazuya; Inoue, Yukio;, Assignee: Kaken Chemical Co. Ltd. (Tokyo, JP)
Alkoxy-4 (1H)-pyridone derivatives, processes for the preparation thereof, and pharmaceutical compositions containing them
OF THE INVENTION The new alkoxy-4(1H)-pyridone derivatives of the present invention are compounds of formula ##STR2## wherein R.sup.1 is a straight-chained or branched, saturated or unsaturated alkyl... Read More
Inventors: Aranda, Julian; Hartenstein, Johannes; Reck, Reinhard; Schachtele, Christoph; Rudolph, Claus; Osswald, Hartmut; Weinheimer, Gunter;, Assignee: Godecke Aktiengesellschaft (Berlin, DE)
Method and compositions for inhibiting protein kinases
We claim: 1. A method for inhibiting a protein kinase, which comprises: contacting a composition containing a protein kinase with a compound of the formula ##STR5## wherein: R.sub.1 is H, lower alkyl,... Read More
Inventors: Giese, Neill A.; Lokker, Nathalie;, Assignee: Cor Therapeutics, Inc. (So. San Francisco, CA)
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