Identification of drug candidates modulating factor VII-mediated intracellular signaling
OF THE INVENTION The present invention relates to the use of FVII or FVIIa or another TF agonist for the manufacture of a pharmaceutical composition for inducing or enhancing activation of the MAPK s... Read More
Inventors: Kongsbak, Lars; Bergenhem, Niels; Petersen, Lars Christian; Thastrup, Ole; Foster, Don;, Assignee: Novo Nordisk A/S (Bagsvaerd, DK) |
Method for providing enteric coating on solid dosage forms and aqueous compositions therefor
OF THE PREFERRED EMBODIMENTS Extensive investigations have been undertaken by the inventors with an object to solve the above described problems in the prior art enteric coating compositions leading ... Read More
Inventors: Onda, Yoshiro; Muto, Hiroaki; Suzuki, Hiroshi; Maruyama, Kazumasa; Hatayama, Atsushi;, Assignee: Shin-Etsu Chemical Co., Ltd. (Tokyo, JP) |
Method for preparing film coated pharmaceutical preparations and method for improving properties thereof
What is claimed is: 1. A method for providing white colored film coated pharmaceutical preparations, said method comprising the steps of providing pharmaceutical preparations having a film coating mat... Read More
Inventors: Kokubo, Hiroyasu; Sekigawa, Fujio; Chiba, Tohru; Onda, Yoshiro;, Assignee: Shin-Etsu Chemical Co., Ltd. (Tokyo, JP) |
Delayed, sustained-release pharmaceutical preparation
OF THE PREFERRED EMBODIMENTS The preferred delayed, sustained-release pharmaceutical preparation of the present invention is a water soluble core drug surrounded by a hydratable diffusion barrier com... Read More
Inventors: Eichel, Herman J.; Massmann, Brent D.;, Assignee: Kinaform Technology, Inc. (Dayton, OH) |
Delayed, sustained-release diltiazem pharmaceutical preparation
OF THE PREFERRED EMBODIMENTS The preferred delayed, sustained-release pharmaceutical preparation of the present invention is a water soluble core drug surrounded by a hydratable diffusion barrier com... Read More
Inventors: Eichel, deceased, Herman J.; Massmann, Brent D.; Cobb, Jr., Joseph E.;, Assignee: Kinaform Technology, Inc. (Dayton, OH) |
Extended release, film-coated tablet of astemizole and pseudoephedrine
We claim: 1. A four-part tablet comprising: (a) an extended release matrix core comprising pseudoephedrine hydrochloride as the active ingredient, a hydrophilic polymer selected from the group consist... Read More
Inventors: Gilis, Paul Marie Victor; Jans, Eugene Marie Jozef; Gijs, Guido Jozef Maria;, Assignee: Janssen Pharmaceutica N.V. (Beerse, BE) |
Pseudoephedrine hydrochloride extended-release tablets
OF THE PREFERRED EMBODIMENTS In a preferred embodiment of the present invention a combination comprising at least one active ingredient together with hydroxypropylmethylcellulose (HPMC) and microcrys... Read More
Inventors: Irwin, Jack T.; Shah, Shirish A.;, Assignee: L. Perrigo Company (Allegan, MI) |
Orally administrable nifedipine pellet and process for the preparation thereof
OF THE EMBODIMENTS A. A Fast-Release Type of Nifedipine Pellet The fast-release type of nifedipine pellet described in this embodiment comprises: (1) a particulate core, and (2) a nifedipine coating ... Read More
Inventors: Lee, Fang-Yu; Chen, Shan-Chiung; Kuo, Han-Chiang;, Assignee: |
Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer
Ethylcellulose, which is a cellulose ether that is formed by the reaction of ethyl chloride with alkaline cellulose, is completely insoluble in water and gastrointestinal juices, and therefore to dat... Read More
Inventors: Oshlack, Benjamin; Pedi, Jr., Frank; Chasin, Mark;, Assignee: Purdue Pharma LP (Norwalk, CT) |
Tea catechins as cancer specific proliferation inhibitors
The invention described herein encompasses a method of treating cancer or solid tumors comprising the administration of a therapeutically effective amount of catechins, a group of polyphenols found in... Read More
Inventors: Morre , Dorothy M.; Morre , James D.;, Assignee: Purdue Research Foundation (West Lafayette, IN) |
Mucorales fungi for use in preparation of foodstuffs
OF THE INVENTION The fermentation process of the first aspect is suitably conducted in a fermenter vessel adapted for containing the aqueous liquid, such as a vat, and this vessel may be pressurized.... Read More
Inventors: André Geraats, Sigbertus Godefridus Maria; Kruyssen, Fredericus Johannes; Bijl, Hendrik Louis;, Assignee: DSM N.V. (TE Heerlen, NL) |
Herbal-based composition for treating acute and chronic myeloid leukemia
1. A method of treating either CD33+ acute myeloid leukemia or CD33+ chronic myeloid leukemia by administering a pharmaceutically effective amount of compound 3-O-p-coumaryl quinic acid to a subject i... Read More
Inventors: Bandyopadhyay, Santu; Roy, Keshab Chandra; Ray, Mitali; Banerjee, Goutam; Pal, Bikash Chandra; Biswas, Tanusree; Bhattacharya, Samir;, Assignee: Council of Scientific and Industrial Research (New Delhi, IN) |
Stable, pulverulent lycopene formulations, comprising lycopene having a degree of crystallinity of greater than 20%
We claim: 1. A process for the preparation of stable, pulverulent lycopene formulations, comprising lycopene having a degree of crystallinity of greater than 20%, which comprises a) preparing a molecu... Read More
Inventors: Runge, Frank; Auweter, Helmut; Musaeus-Jensen, Nina; Haberkorn, Herbert; Rieger, Jens;, Assignee: BASF Aktiengesellschaft (Ludwigshafen) |
Cosmetic compositions with agglomerated substrates
OF PREFERRED EMBODIMENTS Below, the invention is explained in more detail by means of examples. All percentage references relate to weight (mass) unless otherwise stated. EXAMPLE 1 Production of an A... Read More
Inventors: Golz-Berner, Karin; Zastrow, Leonhard;, Assignee: Lancaster Group GmbH (Mainz, DE) |
Emulsifier-free finely disperse systems of the oil-in-water and water-in-oil type
The invention claimed is: 1. Pickering emulsions, which are finely disperse water-in-oil or oil-in-water systems, comprising (1) an oil phase, (2) an aqueous phase, (3) microfine particles which are m... Read More
Inventors: Gers-Barlag, Heinrich; Anja (Rü, mpel, DE);, Assignee: Beiersdorf AG (Hamburg, DE) |
Isolates of pythium species which are antagonistic to Pythium ultimum
What is claimed is: 1. A biologically pure culture of Pythium isolate N2 having the identifying characteristics of ATCC 20692. 2. A biologically pure culture of Pythium isolate N3 having the identifyi... Read More
Inventors: Baker, Ralph; Lifshitz, Ran;, Assignee: Colorado State University Research Foundation (Fort Collins, CO) |
Bacterial substance and pharmaceutical composition thereof
AND PREFERRED EMBODIMENT The term "treatment" used herein is intended to cover all the controls of diseases including prevention, sustention (i.e. prevention of aggravation), alleviation and therapy.... Read More
Inventors: Ueno, Ryuzo; Ueno, Ryuji; Kita, Hiroshi; Kato, Ichie; Tabata, Akihiko; Hironaka, Takashi;, Assignee: Kabushikikaisha Ueno Seiyaku Oyo Kenkyujo (Hyogo, JP) |
Compounds, compositions, and methods for controlling biofilms
This invention relates to compounds, compositions, and methods for controlling biofilms. "Controlling" a biofilm means disrupting a biofilm and/or preventing biofilm formation, enhancing formation and... Read More
Inventors: Degenhardt, Charles Raymond; Grayling, Rowan Andrew; Dille, Christopher Andrew; Tansky, Cheryl Sue;, Assignee: The Procter & Gamble Company (Cincinnati, OH) |
Cosmetic make-up composition containing a fullerene or mixture of fullerenes as a pigmenting agent
I claim: 1. A cosmetic composition in the form of an oil-in-water or water-in-oil emulsion containing an effective amount of fullerene or mixture of fullerenes as a pigment or filler, and a surfactant... Read More
Inventors: Mellul, Myriam;, Assignee: L'Oreal (Paris, FR) |
Benzylidenenorcamphor derivatives
What is claimed is: 1. A method for screening the skin or hair from the sun comprising applying to the skin or hair a benzylidenenorcamphor compound of the formula I ##STR12## wherein Phe is a phenyl ... Read More
Inventors: Stein, Inge; Schwarz, Michael; Heywang, Ulrich; Kompter, Michael;, Assignee: Merck Patent Gesellschaft Mit Beschrankter Haftung (Darmstadt, DE) |
Cosmetic compositions comprising a film-forming polymer a citric acid ester and a plasticizing agent
We claim: 1. A cosmetic composition for forming a film on skin, eyelashes, eyebrows, hair, or nails comprising: (a) at least one film-forming polymer; (b) at least one citric acid ester of formula (I)... Read More
Inventors: Ramin, Roland; Gabin, Philippe; Frankfurt, Chris;, Assignee: L'Oreal (Paris, FR) |
Triazine derivatives
What is claimed is: 1. A cosmetic preparation, comprising at least one triazine compound of the formula ##STR60## in which R is halogen; straight-chain or branched C.sub.1 -C.sub.22 -alkyl; straight-c... Read More
Inventors: Metzger, Georges; Reinehr, Dieter; Luther, Helmut;, Assignee: Ciba Specialty Chemicals Corporation (Tarrytown, NY) |
Chlorite in the treatment of neurodegenerative disease
The invention features methods of treating a macrophage-associated neurodegenerative disease such as amyotrophic lateral sclerosis (ALS), Alzheimer's disease (AD), or multiple sclerosis (MS) in a subj... Read More
Inventors: McGrath, Michael S.;, Assignee: The Regents of the University of California (Oakland, CA) |
Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose
OF THE INVENTION According to the present invention, it has now been found that important advantages and improvements over prior products containing hydroxypropylmethylcelluloses, as described in U.S... Read More
Inventors: Schor, Joseph M.; Nigalaye, Ashok; Gaylord, Norman G.;, Assignee: Forest Laboratories, Inc. (New York, NY) |
Pharmaceutical composition using albumin as a carrier and process for producing the same
I claim: 1. A process for producing a pharmaceutical composition comprising mixing together at high speed in a solvent 1 to 250 parts by weight of a drug capable of binding to protein and 100 parts by... Read More
Inventors: Satoh, Toshio;, Assignee: Nippon Hypox Laboratories Incorporated (Tokyo, JP) |
Stabilized composition of levothyroxine sodium medication and method for its production
OF THE INVENTION The present invention discloses a new composition for levothyroxine sodium medication which provides for greater shelf life of levothyroxine sodium tablets, because the composition i... Read More
Inventors: Groenewoud, Pieter J.; Wang, Hai;, Assignee: Vintage Pharmaceuticals, Inc. (Charlotte, NC) |
Liquisolid systems and methods of preparing same
OF THE DRAWINGS FIG. 1 is a schematic outline of steps involved in the preparation of liquisolid systems. FIG. 2 is a graph showing the comparative dissolution profiles of prednisone from (1 mg and 5... Read More
Inventors: Spireas, Spiridon; Bolton, Sanford M.;, Assignee: |
Stabilized medicaments containing thyroid hormones
We claim: 1. Stable medicaments containing thyroid hormones, wherein said medicaments comprise sodium thiosulfate as the stabilising component in a ratio of thyroid hormones to sodium thiosulfate of 1... Read More
Inventors: Lahr, Wolfgang; Friese, Andrea; Weickgenannt, Guido;, Assignee: Henning Berlin GmbH & Co. (Berlin, DE) |
Areca food additives and its foods
A series of eatable compounds for preparation areca food additive, which have an excellent effect for reaction with polyphenolic compounds, has been devised by the inventor. This series of eatable co... Read More
Inventors: Shiao, Shin Jen;, Assignee: |
Beverage compositions for human consumption
OF THE PRESENT INVENTION The present invention is based on a number of new discoveries and combinations of such discoveries with known scientific data which are summarized below: (1) The main functio... Read More
Inventors: Stray-Gundersen, James;, Assignee: University of Texas System Board of Regents (Austin, TX) |
Weight Loss and Supplements 
